supported by the National Key Research and Development Program of China(2022YFC2502606);the National Natural Science Foundation of China(No.82170208,82200239);CAMS Innovation Fund for Medical Sciences(No.2022-I2M-C&T-B-121);Tongzhou district Distinguished Young Scholars(No.JCQN2023009);Peking University Health Science Center-University of Michigan College of Medicine Joint Institute for Translational and Clinical Research(BMU2022JI003);the Fundamental Research Funds for the Central Universities.
Engraftment syndrome(ES)is one of the most common complications in the early phase after autologous hematopoietic stem cell transplantation(ASCT),and we aimed to evaluate the incidence and risk factors for ES patients...
Objective To evaluate the advantages and safety of Plerixafor in combination with granulocyte colonystimulating factor(G-CSF)in autologous hematopoietic stem cell mobilization of lymphoma.Methods Lymphoma patients who...
High-dose chemotherapy(HDCT)with autologous hematopoietic stem cell transplantation has been explored and has played an important role in the management of patients with high-risk germ cell tumors(GCTs)who failed to b...
Plerixafor is a stem cell mobilising agent, and when administered along with G-CSF has been shown to improve CD34+ stem cell collections in lymphoma and multiple myeloma patients compared to G-CSF alone. Patients who ...
supported by the National Natural Science Foundation of China(Nos.81773774,81473231,and 81673461);Science Foundation for Distinguished Young Scholars of Jiangsu Province(No.BK20150028);the National Science and Technology Major Project(No.2017ZX09301014);the Project Program of State Key Laboratory of Natural Medicines,China Pharmaceutical University(No.SKLNMZZCX201823);Program for Changjiang Scholars and Innovative Research Team in University(No.IRT1193);the Open Project of State Key Laboratory Cultivation Base for TCM Quality and Efficacy,Nanjing University of Chinese Medicine(No.TCMQ&E201704)
Chemokine 12(CXCL12), also known as stromal cell derived factor-1(SDF-1) and a member of the CXC chemokine subfamily, is ubiquitously expressed in many tissues and cell types. It interacts specifically with the ligand...
Here, we report that chemokine-mimetic plerixafor derivatives could govern tumor-specific delivery and functional effects of nanomaterials. Reduced graphene oxide (rGO) nanosheets were used as a model functional nan...
The existence of cancer stem cells has been wellestablished in acute myeloid leukemia. Initial proof of the existence of leukemia stem cells(LSCs) was accomplished by functional studies in xenograft models making use ...
Testicular germ cell cancer(TGCC) is rare form of malignant disease that occurs mostly in young man between age 15 and 40. The worldwide incidence of TGCC is 1.5 per 100000 man with the highest rates in North Europe. ...