PRODRUG

作品数：211被引量：334H指数：7
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相关机构：北京大学上海大学信息技术有限公司郑州大学更多>>
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相关基金：国家自然科学基金中国博士后科学基金国家重点基础研究发展计划湖北省自然科学基金更多>>
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Pure redox-sensitive paclitaxelemaleimide prodrug nanoparticles: Endogenous albumininduced size switching and improved antitumor efficiency被引量：3
《Acta Pharmaceutica Sinica B》2021年第7期2048-2058,共11页Xinyu Lou Dong Zhang Hao Ling Zhonggui He Jin Sun Mengchi Sun Dongchun Liu 
supported by National Natural Science Foundation of China(No.81773656 and U1608283);Liaoning Revitalization Talents Program(No XLYC1808017,China);Key projects of Technology bureau in Shenyang(No.18400408,China);Key projects of Liaoning Province Department of Education(No.2017LZD03,China);111 Project(D20029,China)
A commercial albumin-bound paclitaxel nano-formulation has been considered a gold standard against breast cancer.However,its application still restricted unfavorable pharmacokinetics and the immunogenicity of exogenou...
关键词：PACLITAXEL ABRAXANE Redox-sensitive Disulfide bond MALEIMIDE Prodrug-based nano-drug delivery systems Prodrug/albumin nanoaggregates Breast cancer treatment 
Integrated prodrug micelles with two-photon bioimaging and pH-triggered drug delivery for cancer theranostics被引量：4
《Regenerative Biomaterials》2020年第2期171-180,共10页Hong Xu Boxuan Ma Jizhou Jiang Sutong Xiao Rongrong Peng Weihua Zhuang Gaocan Li Yunbing Wang 
supported by the National Natural Science Foundation of China(Projects No.21502129);the National 111 Project of Introducing Talents of Discipline to Universities(No.B16033);China Postdoctoral Science Foundation Funded Project(Nos.2017M612956,2018T110969);the State Key Laboratory of Polymer Materials Engineering(No.sklpme2018-3-05)。
Nanodrug carriers with fluorescence radiation are widely used in cancer diagnosis and therapy due to their real-time imaging,less side effect,better drug utilization as well as the good bioimaging ability.However,trad...
关键词：aggregation-induced emission TWO-PHOTON PH-SENSITIVE charge reversal drug delivery system 
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