VIROLOGIC

作品数：20被引量：90H指数：6
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相关期刊：《World Journal of Gastroenterology》《Advances in Infectious Diseases》《World Journal of AIDS》《World Journal of Hepatology》更多>>
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Sustained virologic response to direct-acting antiviral agents predicts better outcomes in hepatitis C virus-infected patients: A retrospective study被引量：10
《World Journal of Gastroenterology》2019年第40期6094-6106,共13页Gian Luca Colussi Debora Donnini Rosario Francesco Brizzi Silvia Maier Luca Valenti Cristiana Catena Alessandro Cavarape Leonardo Alberto Sechi Giorgio Soardo 
BACKGROUND Direct-acting antiviral agents(DAAs)are extremely effective in eradicating hepatitis C virus(HCV)in chronically infected patients.However,the protective role of the sustained virologic response(SVR)achieved...
关键词：Direct-acting ANTIVIRAL agents Hepatitis C virus Mixed CRYOGLOBULINEMIA SUSTAINED VIROLOGIC response Cirrhosis Survival analysis 
Consensus on management of hepatitis C virus infection in resource-limited Ukraine and Commonwealth of Independent States regions
《World Journal of Gastroenterology》2019年第29期3897-3919,共23页Massimo Giuseppe Colombo Erkin Isakovich Musabaev Umed Yusupovich Ismailov Igor A Zaytsev Alexander V Nersesov Igor Anatoliyevich Anastasiy Igor Alexandrovich Karpov Olga A Golubovska Kulpash S Kaliaskarova Ravishankar AC Sanjay Hadigal 
Globally, 69.6 million individuals were infected with hepatitis C virus (HCV) infection in 2016. Of the six major HCV genotypes (GT), the most predominant one is GT1, worldwide. The prevalence of HCV in Central Asia, ...
关键词：ANTIVIRAL agents COMMONWEALTH of Independent States GENOTYPE Hepatitis C virus SUSTAINED VIROLOGIC response Ukraine 
Interferon-λ polymorphisms and response to pegylated interferon in Iranian hepatitis C patients
《World Journal of Gastroenterology》2015年第29期8935-8942,共8页Arghavan Haj-sheykholeslami Maryam Keshvari Heidar Sharafi Ali Pouryasin Khalil Hemmati Fatemeh Mohammadzadehparjikolaei 
Supported by Pooyesh Darou which is the local manufacturer of pegylated interferon alpha-2a in Iran(Pegaferon)
AIM: To evaluate the efficacy of pegylated interferon in Iranian chronic hepatitis C patients in relation to interferon-λ(IFNL) polymorphisms. METHODS: This study enrolled patients with chronic hepatitis C referred t...
关键词：Chronic hepatitis C Pegylated INTERFERON rs12979860 rs8099917 Sustained VIROLOGIC RESPONSE 
Covalently closed-circular hepatitis B virus DNA reduction with entecavir or lamivudine被引量：14
《World Journal of Gastroenterology》2015年第15期4644-4651,共8页Scott Bowden Stephen Locarnini Ting-Tsung Chang You-Chen Chao Kwang-Hyub Han Robert G Gish Robert A de Man Miao Yu Cyril Llamoso Hong Tang 
Supported by Bristol-Myers Squibb
AIM: To investigate the reduction in hepatitis B virus(HBV) covalently closed-circular DNA(ccc DNA) with entecavir(ETV) or lamivudine(LAM). METHODS: This analysis included patients who had participated in the randomiz...
关键词：HEPATITIS B VIRUS Nucleos(t)ide analogtherapy INTRAHEPATIC HEPATITIS B VIRUS DNA Antiviralsuppression VIROLOGIC cure 
Sofosbuvir and ABT-450: Terminator of hepatitis C virus?被引量：6
《World Journal of Gastroenterology》2013年第21期3199-3206,共8页Qing-Lei Zeng Ji-Yuan Zhang Zheng Zhang Li-Feng Wang Fu-Sheng 
Supported by Grants from the National Key Basic Research Program of China, No. 2009CB522507, No. 2012CB519005;Beijing Nova Program of China, No. Z12110702512071
Combination therapy with peginterferon (pegIFN)-α and ribavirin (RBV) has been the standard of care (SOC) for chronic hepatitis C. Unfortunately, not all patients can achieve a sustained virologic response (SVR) with...
关键词：Sofosbuvir ABT-450 HEPATITIS C virus ANTIVIRAL therapy SUSTAINED VIROLOGIC response 
Virologic characteristics of hepatitis B virus in patients infected via maternal-fetal transmission被引量：11
《World Journal of Gastroenterology》2008年第37期5674-5682,共9页Tao Shen Xin-Min Yan Yun-Lian Zou Jian-Mei Gao Hong Dong 
The Natural Science Foundation of Yunnan Province, No.200300172;Hospital Science Foundation of The First People’s Hospital of Yunnan Province (2004)
AIM: To determine whether HBV with the same characteristics causes dissimilar mutations in different hosts. METHODS: Full-length HBV genome was amplified and linked with pMD T18 vector. Positive clones were selected b...
关键词：Hepatic B virus Vertical transmission Fullgenome Mutation PHYLOGENETIC DELETION 
Clinical, virologic and phylogenetic features of hepatitis B infection in Iranian patients
《World Journal of Gastroenterology》2008年第35期5448-5453,共6页Golnaz Bahramali Majid Sadeghizadeh Samad Amini-Bavil-Olyaee Seyed-Moayed Alavian Abbas Behzad-Behbahani Ahmad Adeli Mohammad-Reza Aghasadeghi Safieh Amini Fereidoun Mahboudi 
A grant from the Nanotechnology committee of the Ministry of Science, Research and Technology, Iran, No. 31.1895 on 05.03.2004 to Majid Sadeghizadeh
AIM： To characterize the clinical, serologic and virologic features of hepatitis B virus （HBV） infection in Iranian patients with different stages of liver disease.METHODS： Sixty two patients comprising of 12 inac...
关键词：Hepatitis B virus Clinical and virologic features Genetic variability Phylogenetic analysis 
Baseline HBV DNA level is the most important factor associated with virologic breakthrough in chronic hepatitis B treated with lamivudine被引量：20
《World Journal of Gastroenterology》2007年第30期4085-4090,共6页Hee Bok Chae Hie-Won Hann 
Supported by the research grant of the Chungbuk National University in 2004
AIM: To identify the factors associated with virologic breakthrough and to select a subgroup of patients who respond well to lamivudine without developing virologic breakthrough (VBT). METHODS: Of 79 patients who had ...
关键词：Hepatitis B LAMIVUDINE Virologic breakthrough HBV DNA 
Intra-familial prevalence of hepatitis B virologic markers in HBsAg positive family members in Nahavand, Iran被引量：8
《World Journal of Gastroenterology》2005年第31期4857-4860,共4页Amir Houshang Mohammad Alizadeh Mitra Ranjbar Shahin Ansari Seyed Moayed Alavian Hamid Mohaghegh Shalmani Leila Hekmat Mohammad Reza Zali 
AIM, To determine the prevalence of hepatitis B in Nahavand and evaluate the HBsAg positive prevalence in families with a member who was confirmed to have HBV infection. METHODS： This study was performed in two phase...
关键词：Intra-familial prevalence Hepatitis B Nahavand Iran 
Ribavirin monotherapy increases sustained response rate in relapsers of end treatment virologic responders
《World Journal of Gastroenterology》2005年第11期1663-1667,共5页Cho-LiYen Jia-JangChang Tsung-ShihLee Ching-JungLiu Li-WeiChen Liang-CheChang 
Supported by the Chang Gung Memorial Hospital Medical Research Program CMRPG-2044 and CMRP-800-VI
AIM: To assess the efficacy of ribavirin monotherapy in patients with biochemical relapse after combination therapy.METHODS: Twenty-four weeks of ribavirin monotherapy was given to biochemical relapsers of end treatme...
关键词：Ribavirin monotherapy Interferon-α plus iribavirin combination therapy Relapser End treatment virologic responder 
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