Objective To analyze the efficacy and safety of integrase inhibitor-based single-tablet regimens bictegravir/emtricitabine/tenofovir alafenamide (B/F/TAF) and lamivudine/dolutegravir (3TC/DTG) in the treatment-naive p...
supported by the Gilead Sciences and the Capital Health Research and Development of Special Fund(No.2022-1G-3015)
Background:Antiretroviral therapy(ART)was often associated with dyslipidemia among human immunodeficiency virus(HIV)/acquired immunodeficiency syndrome(AIDS)patients.This study aimed to assess treatment-naïve adult ma...
Background:Dual regimen dolutegravir(DTG)plus lamivudine(3TC)has demonstrated non-inferior efficacy compared to DTG-based three-drug regimens(3DRs),yet directly comparative data regarding the efficacy and safety of DT...
Supported by National Natural Science Foundation of China(General Program),No.82070610.
BACKGROUND How to treat infantile hepatitis B virus(HBV)infection remains a controversial issue.The nucleoside analogue lamivudine(LAM)has been approved to treat children(2 to 17 years old)with chronic hepatitis B.Her...
supported by the National Key R&D Program of China(Nos.2017YFE0102200,2017YFC0908600);Zhejiang Provincial Natural Science Foundation of China(LY15H310004,LY16H280014);Natural Science Foundation of China(No.81573502)
Stellera chamaejasme L.is a traditional Chinese medicine with a long history to treat stubborn skin ulcer,and it also has antiviral and antitumor effects.Neochamaejasmine B(NCB),Neochamaejasmine A(NCA)and Chamaechromo...
Background and Aims:The perinatal transmission of hepatitis B virus(HBV)remains an important global health problem.Here,a systematic review and meta-analysis were conducted to evaluate the evidence regarding the effic...
Perinatal transmission of hepatitis B virus (HBV) in-fection is major contributor to the growing burden of chronic hepatitis B worldwide. Administration of HBV immunoglobulin and HBV vaccination as soon after pre-gn...
Worldwide, hepatocellular carcinoma (HCC) is a significant cause of morbidity and mortality. In men, it is the fifth most common cancer and seventh most common in women;HCC is the second highest cause of cancer-relate...