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作品数:443被引量:375H指数:6
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相关作者:王锦艳蹇锡高王兰芝韩立杨鹰更多>>
相关机构:大连理工大学中国科学院北京大学中南大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金国家高技术研究发展计划更多>>
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Synthesis of C2-Spiroindolines Based on the Cascade Reaction of 2-Aryl-3H-indoles with Cyclopropanols
《有机化学》2025年第2期694-706,共13页Xueying Yang Yuanshuang Xu Xinying Zhang Xuesen Fan 
国家自然科学基金(U2004189);中原科技创新领军人才项目(224200510009);河南省博士后基金(HN2022041)。
A novel synthesis of C2-spiroindoline derivatives based on the cascade reaction of 2-aryl-3H-indoles with cyclo- propanols is presented. The formation of product involves Rh(III)-catalyzed aryl C(sp2)—H bond alkylati...
关键词:C2-spiroindolines SYNTHESIS C-H bond activation cascade reaction 2-aryl-3H-indoles CYCLOPROPANOLS 
Discovery of a novel AhReCYP1A1 axis activator for mitigating inflammatory diseases using an in situ functional imaging assay
《Acta Pharmaceutica Sinica B》2025年第1期508-525,共18页Feng Zhang Bei Zhao Yufan Fan Lanhui Qin Jinhui Shi Lin Chen Leizhi Xu Xudong Jin Mengru Sun Hongping Deng Hairong Zeng Zhangping Xiao Xin Yang Guangbo Ge 
supported by National Natural Science Foundation of China(Nos.U23A20516,81922070,82273897 and 52303191);National Key Research and Development Program of China(No.2022YFC3502000);Shanghai Science and Technology Innovation Action Plans(21S21900600,China);the Organizational Key Research and Development Program of Shanghai University of Traditional Chinese Medicine(No.2023YZZ02,China);Shanghai Municipal Health Commission’s TCM research project(No.2022CX005,China);Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine(No.ZYYCXTDD-202004,China);the State Key Laboratory of Fine Chemicals,Dalian University of Technology(No.KF 2202,China);Shanghai University of Traditional Chinese Medicine(No.2021LK023,China).
The aryl hydrocarbon receptor(AhR)plays a crucial role in regulating many physiological processes.Activating the AhReCYP1A1 axis has emerged as a novel therapeutic strategy against various inflammatory diseases.Here,a...
关键词:Aryl hydrocarbonreceptor(AhR) Cytochrome P4501A1(CYP1A1) In situ functional imaging Ulcerative colitis(UC) Acute lung injury(ALI) Long term imaging Rational design Inflammatory diseases 
Synergistic BrΦnsted/Lewis acid catalyzed atroposelective synthesis of aryl-β-naphthol
《Chinese Chemical Letters》2025年第1期293-298,共6页Jiajun Lu Zhehui Liao Tongxiang Cao Shifa Zhu 
financial support from the National Natural Science Foundation of China(Nos.22071062,22001077 and 22271096);Guangdong Science and Technology Department(Nos.2021A1515012331,2023A1515011001);the Fundamental Research Funds for the Central Universities(No.2022ZYGXZR016);South China University of Technology for start-up funds。
Axially chiral binaphthol have achieved great success in asymmetric catalysis.Compared toα-binaphthol,axially chiral aryl-β-naphthol are far less reported.Here,we report a method of asymmetric catalysis to construct...
关键词:Synergistic catalysis ATROPISOMERISM Aryl-β-naphthol ENANTIOSELECTIVITY Tandem reaction 
Catalytic Asymmetric Conjugate Addition and Allylic Substitution of Cyclobutenones with Arylzinc Halides
《Chinese Journal of Chemistry》2025年第2期184-190,共7页Renming Pan Ping Lu 
supported by the National Natural Science Foundation of China(22071028,21921003).
Conjugate addition and allylic substitution are two essential chemical transformations,and they could be competitive for substrates with multiple reactive sites.Herein,we report the diversified enantioselective synthe...
关键词:Asymmetric conjugate addition Asymmetric allylic substitution Aryl transfer CHEMOSELECTIVITY Chiral quaternary stereocenters Cross-coupling/Strainedmolecules 
Reactions of Alkynyl Aryl Phosphine Oxide with Oxalyl Bromide
《有机化学》2024年第12期3753-3760,共8页Zhao Peng Gan Zhenjie Li Zhuo Wang Lili Duan Zheng 
国家自然科学基金(Nos.22101262,22171245);河南省科技攻关(No.242102230166)资助项目.
Tertiary phosphines and their oxides react with oxalyl bromide to generate corresponding quaternary phosphonium salts,which can be further transformed as active intermediates to facilitate the bromination of alcohols ...
关键词:aryl phosphine oxide benzyl phosphine oxide oxalyl bromide quaternary phosphonium salt ALKYNE 
Interface strengthening for carbon fiber-reinforced poly(ether-ether-ketone)laminated composites by introducing fluorene-containing branched poly(aryl-ether-ketone)
《Interdisciplinary Materials》2024年第6期919-934,共16页Zheng Liu Xuerong Fan Xinghan Lu Xuetao Shi Junliang Zhang Hua Guo Mukun He Junwei Gu 
Innovation Capability Support Program of Shaanxi,Grant/Award Number:2024RS‐CXTD‐57;Innovation Foundation for Doctor's Dissertation of Northwestern Polytechnical University,Grant/Award Number:CX2023026;Undergraduate Innovation&Business Program in Northwestern Polytechnical University,Grant/Award Number:202310699253。
Fluorene-containing branched poly(aryl-ether-ketone)(BFPAEK)with terminal hydroxyl groups is synthesized by random copolycondensation reaction;then,the CF@BFPAEK/PEEK laminated composite is prepared by the“powder imp...
关键词:carbon fiber fluorene-containing branched poly(aryl-ether-ketone) laminated composites poly(ether-ether-ketone) 
Oxidative spirolactonisation for modular access of γ-spirolactones via a radical tandem annulation pathway
《Chinese Chemical Letters》2024年第10期249-252,共4页Jindian Duan Xiaojuan Ding Pui Ying Choy Binyan Xu Luchao Li Hong Qin Zheng Fang Fuk Yee Kwong Kai Guo 
the National Natural Science Foundation of China(No.22078150);the Natural Science Foundation of Jiangsu Province,Frontier Project(No.BK20212003)for their financial support;the RGC of Hong Kong(No.14308922);the Guangdong Research Fund(No.2022A1515010955);CUHK Direct Grant(No.4053559)。
An oxidative annulation of 2-arylidene-1,3-indanediones with Meldrum's acid has been developed for the divergent syntheses of spirolactones with a spirocenter located at theγ-position with respect to the carbonyl gro...
关键词:Spirolactonisation y-Spirolactones 2-Arylidene-1 3-indanediones Meldrum's acid Divergentsynthesis 
Unraveling the roles of atomically-dispersed Au in boosting photocatalytic CO_(2)reduction and aryl alcohol oxidation
《Chinese Journal of Catalysis》2024年第10期163-173,共11页Jian Lei Nan Zhou Shuaikang Sang Sugang Meng Jingxiang Low Yue Li 
国家重点研发计划项目(2022YFE0126500);国家杰出青年科学基金项目(51825103);国家自然科学基金项目(92263209,52002142,22150610467,52261135635);安徽省杰出青年科学基金项目(2022AH020038).
Atomically-dispersed metal-based materials represent an emerging class of photocatalysts attributed to their high catalytic activity,abundant surface active sites,and efficient charge separation.Nevertheless,the roles...
关键词:Photocatalysis Atomically-dispersed metal SINGLE-ATOM CO_(2)reduction Aryl alcohol oxidation 
Visible-Light-Induced Selective Hydrocarboxylation of Alkynes with Formate
《有机化学》2024年第10期3241-3248,共8页Xu Hui Jiang Huixian Kan Lei Xu Pei Zhu Xu 
江苏省特聘教授(2020)资助项目。
An efficient and sustainable protocol for regioselective hydrocarboxylation of alkynes to construct diverse propionic acid derivatives is disclosed.Under photoinduced conditions,the anti-Markovnikov hydrocarboxylation...
关键词:FORMATE CO_(2)radical anion HYDROCARBOXYLATION visible-light catalysis aryl propionic acids 
Solvent-Controlled Sc(OTf)_(3)-Catalyzed Ring Opening Reaction of 2-(Hetero)aryl-N-sulfonylazetidines:Synthesis of Allylic Amines/1,3-Oxazinane Derivatives
《有机化学》2024年第9期2796-2809,共14页Zhu Jie Tang Sidan Kan Xiumei Fan Shizhu Wang Pengfei Yang Peijun 
国家自然科学基金(No.22001007);安徽工程大学科研基金(No.2020YQQ025);安徽省重点分子基材料省级实验室开放基金(No.fzj22012)资助项目.
Allylic amines and 1,3-oxazinanes are valuable molecular skeletons in organic synthesis and pharmaceutical industry.A straightforward way to such two types of compounds by solvent-controlled rare-earth metal Lewis aci...
关键词:rare-earth metal Lewis acid solvent control AZETIDINE regioselectivity ring opening reaction 
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