HITCHHIKING

作品数：12被引量：24H指数：3
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相关领域：生物学更多>>
相关作者：孙巍更多>>
相关机构：辽宁大学更多>>
相关期刊：《BMEMat(BioMedical Engineering Materials)》《Frontiers of Computer Science》《Bioactive Materials》《城市漫步（GBA版）》更多>>
相关基金：国家自然科学基金更多>>
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Nanomedicine hitchhiking on bacteria for treating tumors
《BMEMat(BioMedical Engineering Materials)》2024年第4期111-129,共19页Shujing Zheng Xingwei Li Shutao Guo 
The authors thank the support of the National Natural Science Foundation of China(Nos:32171386,32201157,and U23A20488);the Natural Science Foundation of Tianjin of China(No:21JCZDJC01250).
Nanomedicine has shown promising therapeutic potential in cancer treatment,with clinically approved formulations such as DoxilR and AbraxaneR already providing tangible benefits to patients.However,challenges such as ...
关键词：BACTERIA cancer therapy drug delivery HITCHHIKING NANOMEDICINE 
Cell carriers change the in vivo fate of nanoparticles
《Acta Pharmaceutica Sinica B》2024年第12期5515-5517,共3页Xiaotong Li Jianhua He Wei He 
supported by the National Natural Science Foundation of China(Nos.82073782 and 82241002);the Shanghai Science and Technology Committee(No.19430741500,China);the Key Laboratory of Modern Chinese Medicine Preparation of Ministry of Education of Jiangxi University of Traditional Chinese Medicine(zdsys-202103,China).
Drug delivery systems(DDSs)involved with nano/microparticles enjoy a superior advantage in accurately delivering drugs to the desired sites for higher therapeutic efficacies and lower side ef-fects.Unfortunately,the c...
关键词：Cell carriers Drug delivery systems Precision therapy Fate of nano/microparticles Cyto-adhesive micropatches Drug hitchhiking Long circulation delivery system Targeted delivery 
Robust reactive oxygen species modulator hitchhiking yeast microcapsules for colitis alleviation by trilogically intestinal microenvironment renovation被引量：1
《Bioactive Materials》2024年第6期203-220,共18页Jintao Li Jian Song Zhichao Deng Jian Yang Xiaoqin Wang Bowen Gao Yuanyuan Zhu Mei Yang Dingpei Long Xiaoqin Luo Mingxin Zhang Mingzhen Zhang Runqing Li 
supported by the National Natural Science Foundation of China(Nos.52103183,32360176);the Shaanxi Province Key Research and Development Program(No.2023-YBSF-072);the Natural Science Basic Research Program of Shaanxi(Nos.2021JQ-382,2024JC-YBMS-664);the Fundamental Research Funds for the Central Universities,China(No.xtr052023008);the Innovation Team of Xi’an Medical University(No.2021TD15);the Young Talent Support Plan of Xi’an Jiaotong University,China(No.YX6J001).
Ulcerative colitis(UC)is characterized by chronic inflammatory processes of the intestinal tract of unknown origin.Current treatments lack understanding on how to effectively alleviate oxidative stress,relieve inflamm...
关键词：Ulcerative colitis Metal polyphenol network Reactive oxygen species Yeast microcapsules Intestinal microenvironment 
Salmonella-mediated blood-brain barrier penetration,tumor homing and tumor microenvironment regulation for enhanced chemo/bacterial glioma therapy被引量：7
《Acta Pharmaceutica Sinica B》2023年第2期819-833,共15页Ze Mi Qing Yao Yan Qi Jinhai Zheng Jiahao Liu Zhenguo Liu Hongpei Tan Xiaoqian Ma Wenhu Zhou Pengfei Rong 
supported by the National Natural Science Foundation of China(Nos.U1903125,82071986,82073799,and 81771827);Natural Science Foundation of Hunan province in China(2021JJ20084);the Science and Technology Project of Hunan Province(2021RC4017 and 2021RC3020,China);the Furong Scholars Programme of Hunan Province;the Wisdom Accumulation and Talent Cultivation Project of the Third Xiangya Hospital of Central South University(China)。
Chemotherapy is an important adjuvant treatment of glioma,while the efficacy is far from satisfactory,due not only to the biological barriers of blood-brain barrier(BBB)and blood-tumor barrier(BTB)but also to the intr...
关键词：GLIOMA Neutrophil hitchhiking Blood-brain barrier Chemo-sensitization Outer membrane vesicles Doxorubicin P-GLYCOPROTEIN Salmonella 
Characterization of the interaction of nanobubble ultrasound contrast agents with human blood components被引量：3
《Bioactive Materials》2023年第1期642-652,共11页Michaela B.Cooley Eric C.Abenojar Dana Wegierak Anirban Sen Gupta Michael C.Kolios Agata A.Exner 
supported by the Hematopoietic Biorepository and Cellular Therapy Shared Resource of the Case Comprehensive Cancer Center(P30CA043703);the NIH grants T32GM007250,T32HL134622,,F30HL160111;the National Institute of Biomedical Imaging and Bioengineering(R01EB025741,R01EB028144).
Nanoscale ultrasound contrast agents,or nanobubbles,are being explored in preclinical applications ranging from vascular and cardiac imaging to targeted drug delivery in cancer.These sub-micron particles are approxima...
关键词：NANOBUBBLES Ultrasound contrast agents Red blood cells HITCHHIKING ULTRASOUND Drug delivery 
Citywide package deliveries via crowdshipping:minimizing the efforts from crowdsourcers被引量：1
《Frontiers of Computer Science》2022年第5期57-69,共13页Sijing CHENG Chao CHEN Shenle PAN Hongyu HUANG Wei ZHANG Yuming FENG 
This work was supported in part by the National Natural Science Foundation of China(Grant No.61872050);in part by the Chongqing Basic and Frontier Research Program(cstc2018jcyjAX0551);Foundation of Chongqing Municipal Key Laboratory of Institutions of Higher Education([2017]3);Foundation of Chongqing Development and Reform Commission(2017[1007]);Foundation of Chongqing Three Gorges University.Sijing Cheng and Chao Chen contributed equally to this work.Wei Zhang is the corresponding authors for this paper.
Most current crowdsourced logistics aim to minimize systems cost and maximize delivery capacity,but the efforts of crowdsourcers such as drivers are almost ignored.In the delivery process,drivers usually need to take ...
关键词：crowdshipping hitchhiking rides dynamic delivery optimization package delivery taxi scheduling 
Fucoidan-functionalized activated platelet-hitchhiking micelles simultaneously track tumor cells and remodel the immunosuppressive microenvironment for efficient metastatic cancer treatment被引量：3
《Acta Pharmaceutica Sinica B》2022年第1期467-482,共16页Rong Guo Miao Deng Xuan He Mengmeng Li Jiaxin Li Penghui He Houqin Liu Man Li Zhirong Zhang Qin He 
supported by National Natural Science Foundation of China(81974499 and 81690261);Sichuan Science and Technology Program(2018RZ0136)。
Tumor metastasis is responsible for most mortality in cancer patients, and remains a challenge in clinical cancer treatment. Platelets can be recruited and activated by tumor cells, then adhere to circulating tumor ce...
关键词：FUCOIDAN Activated platelets P-selectin Platelets-hitchhiking Track tumor cells TGF-β Reverse immunosuppressive microenvironment Tumor metastasis 
Cell relay-delivery improves targeting and therapeutic efficacy in tumors
《Bioactive Materials》2021年第6期1528-1540,共13页Ye Feng Qianqian Liu Yi Li Yang Han Meng Liang Hao Wang Qing Yao Yuli Wang Meiyan Yang Zhiping Li Wei Gong Yang Yang Chunsheng Gao 
We are grateful for the financial support from National Natural Science Foundation of China(No.82073783);National Science and Technology Major Projects for“Major New Drugs Innovation and Development”(Grant No.2018ZX09711003-008-001).
Cell-mediated drug delivery system(CDDS)has shown great potential for cancer therapy.However,a single cell-mediated drug delivery mechanism has not generally been successful,particularly for systemic administration.To...
关键词：Cell relay-delivering Cell-mediated drug delivery HITCHHIKING Solid tumor 
END OF THE ROAD Dump truck hitchhiking in Kyrgyzstan
《城市漫步（GBA版）》2015年第1期42-42,共1页LEE MOORE GALEN BURKE(PHOTOS) 
0ver two months,Galen and I had gone from Xi'an to Kashgar;traveling over 5,000 kilometers.We had climbed imperial Huashan Mountain,explored holy Tibetan lakes,hitchhiked with Tibetan cops,camped in the desert and eve...
关键词：TIBETAN RETURN MOUNTAINS 
Hitchhiker＇s guide to genetic diversity in socially structured populations
《Current Zoology》2012年第2期287-297,共11页L. S. PREMO 
When selection increases the frequency of a beneficial gene substitution it can also increase the frequencies of linked neutral alleles through a process called genetic hitchhiking. A model built to investigate reduce...
关键词：Cultural group selection Cultural hitchhiking Culturally mediated migration Diversity Evolution Genetic hitch- hiking 
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