CELASTROL

作品数：55被引量：194H指数：9
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相关机构：南昌大学第一附属医院中山大学南京师范大学广州医科大学更多>>
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Neuroinflammation attenuation effects by celastrol and PDIA3 in the amygdala, hippocampus and dorsal raphe nucleus of obese mice
《Journal of Pharmaceutical Analysis》2024年第2期287-290,共4页Chunyan Zhu Xuemin Yao Dandan Liu Guoxin Zhang Yongping Zhu Hongyu Chi Shuangpan Zhang Jun Yang Ying Liu Jigang Wang Na Lin 
supported by the grants from the Natural Science Foundation of Beijing Municipality(Grant No.:7212185);the Scientific and Technological Innovation project of China Academy of Chinese Medical Sciences(Grant No.:CI2021A03808);the National Natural Science Foundation of China(Grant Nos.:82330124,81974526,and 82274176);the Innovation Team and Talents Cultivation Program of the National Administration of Traditional Chinese Medicine,China(Program No.:ZYYCXTD-C-202002);the Special Project for Training Outstanding Young Scientific and Technological Talents(innovative type)of Necessary Scientific Research Business Expenses of China Academy of Chinese Medical Sciences(Project Nos.:ZZ13-YQ-051,and ZZ15-YQ-063);the Fundamental Research Funds for the Central public welfare research institutes(Grant No.:ZXKT21010).
Nowadays,roughly 603.7 million people are bothered by obesity[1].More seriously,obesity brings inflammation to the peripheral and central nervous system,which compromises the comorbidity of obesity,major depression[2]...
关键词：inflammation OBESITY OBESE 
Celastrol targeting Nedd4 reduces Nrf2-mediated oxidative stress in astrocytes after ischemic stroke被引量：4
《Journal of Pharmaceutical Analysis》2023年第2期156-169,共14页Zexuan Hong Jun Cao Dandan Liu Maozhu Liu Mengyuan Chen Fanning Zeng Zaisheng Qin Jigang Wang Tao Tao 
the National Natural Science Foundation of China(Grant No.:81973305);the Science and Technology Planning Project of Guangzhou,China(Grant No.:201904010487);the Natural Science Foundation of Guangdong Province,China(Grant No.:2021A1515010897);the Discipline Construction Fund of Central People’s Hospital of Zhanjiang(Grant Nos.:2020A01 and 2020A02).
Stroke is the second leading cause of death worldwide,and oxidative stress plays a crucial role.Celastrol exhibits strong antioxidant properties in several diseases;however,whether it can affect oxidation in cerebral ...
关键词：CELASTROL Cerebral ischemia Reperfusion injury Oxidative stress Nedd4 Nrf2 UBIQUITYLATION 
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