supported by an NIH NIAMS P30 AR069655 pilot grant (G.M.) with additional support from NIH NIAID R21 AI69736 (G.M.);NIH NIAMS P50 AR072000(E.M.S.);P30 AR069655 (E.M.S.);the AO Trauma Clinical Priority Program (E.M.S.,S.L.K.);internal funds of the Department of Medicine and R01A111914 (J.R.M.)。
Interleukin-27 is a pleiotropic cytokine whose functions during bacterial infections remain controversial,and its role in patients with S.aureus osteomyelitis is unknown.To address this knowledge gap,we completed a cl...
supported in part by funds from the breast cancer advocacy group 100 Voices of Hope, as well as by NIHR01 AR52144, R03 CA238555 (HY) and R01 AR053237 (AGR).NIHR01 AR52144,R03 CA238555 (HY) and R01 AR053237 (AGR);100 Voices of Hope (HY)。
Osteocytes are mechanosensitive bone cells, but little is known about their effects on tumor cells in response to mechanical stimulation. We treated breast cancer cells with osteocyte-derived conditioned medium(CM) an...
supported by grants from the National Research Foundation of Korea (NRF2017R1A2A1A17069648 and NRF-2018R1A5A2024418) to H.-H.K.;the National Research Foundation of Korea (NRF-2017R1D1A1B03028003) to H.K.
Bone destruction induced by breast cancer metastasis causes severe complications,including death,in breast cancer patients.Communication between cancer cells and skeletal cells in metastatic bone microenvironments is ...
In a world where increasing joint arthroplasties are being performed on increasingly younger patients, osteolysis as the leading cause of faiIure after total joint arthroplasty (TJA) has gained considerable attentio...