OSTEOLYSIS

作品数：38被引量：88H指数：6
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相关领域：医药卫生更多>>
相关作者：谭艳辉邹斌华李晓娟程晓光汪学军更多>>
相关机构：广西医科大学北京丰盛医院南方医科大学苏州大学更多>>
相关期刊：《Chinese Journal of Traumatology》《Cellular & Molecular Immunology》《Acta Pharmacologica Sinica》《Open Journal of Orthopedics》更多>>
相关基金：国家自然科学基金上海市自然科学基金国家重点基础研究发展计划更多>>
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Long-term follow-up result of short metaphyseal femoral stem in primary total hip arthroplasty:A retrospective study
《World Journal of Orthopedics》2025年第1期40-45,共6页Manoj Kumar Ayush Sharma Vivek P Ksheerasagar Akash K Ghosh Mukund Lal 
BACKGROUND Total hip arthroplasty(THA)has increased along with an increasing demand for improved quality of life.Combined with prolonged life expectancy,the number of revision surgeries is expected to increase.Stress ...
关键词：Short stem total hip replacement Short metaphyseal stem Uncemented hip replacement Proximal femur osteolysis Proximal femur bone loss 
Aggregation-induced emission biomarkers for early detection of orthopaedic implant failure
《Aggregate》2024年第6期93-108,共16页Javad Tavakoli Qi Hu Joanne L.Tipper Youhong Tang 
In recent years,the substantial increase in total joint replacements for treating degenerative joint disease has heightened concerns regarding implant loosening and failure.This is especially critical as more young pa...
关键词：aggregation-induced emission biomarkers early detection implant failure orthopaedic implants OSTEOLYSIS 
Suppression of NFATc1 through NF-kB/PI3K signaling pathway by Oleandrin to inhibit osteoclastogenesis and bone resorption
《Engineered Regeneration》2024年第3期342-349,共8页Zhikun Li Kai Chen Qifeng Yu Yifan Li Shichao Tong Ruijun Xu Ruixi Hu Yi Zhang Wei Xu 
National Natural Science Foundation of China(82272165);Shanghai Municipal Commission of Health and Family Planning’s Science and Research Fund(202040141);Shanghai Municipality Science and Technology Commission(20ZR1451800,22ZR1457200);Shanghai Municipal Health Commission(2022YQ006);Shanghai Tongren Hospital(TRKYRC-xx202203).
Inflammation can initiate osteolysis,which is the breakdown of bone by fully developed osteoclasts.The com-pound Oleandrin is recognized for its effects against inflammation and tumors.Our objective was to examine the...
关键词：OSTEOCLASTOGENESIS OSTEOLYSIS NF-κB PI3K Oleandrin NFATc1 
Reduced expression of semaphorin 3A in osteoclasts causes lymphatic expansion in a Gorham-Stout disease(GSD)mouse model
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2024年第1期38-50,共13页Dongfang ZHANG Hao XU Chi QIN Kangming CAI Jing ZHANG Xinqiu XIA Jingwen BI Li ZHANG Lianping XING Qianqian LIANG Wensheng WANG 
supported by the National Natural Science Foundation of China(No.81974321);the Discipline Innovation and Talent Introduction Program to Universities from Ministry of Education of China(Project 111);the Tackling Project for Science and Technology of Xinxiang City(No.GG2019003);the Natural Science Foundation of Henan Province of China(No.212300410173);the State Administration of Traditional Chinese Medicine Young Qi Huang Scholar,and the Innovation Team Project of Scientific Research of Traditional Chinese Medicine of Shanghai Health Committee(No.2022CX001);China.
Gorham-Stout disease(GSD)is a sporadic chronic disease characterized by progressive bone dissolution,absorption,and disappearance along with lymphatic vessel infiltration in bone-marrow cavities.Although the osteolyti...
关键词：Semaphorin 3A Gorham-Stout disease OSTEOCLAST OSTEOLYSIS Lymphatic endothelial cell 
Cementless Buechel-Pappas Resurfacing Total Hip Replacement: A 45-Year Personal Journey to Overcome Wear, Osteolysis, Loosening and Femoral Neck Fractures
《Open Journal of Orthopedics》2023年第10期435-442,共8页Frederick F. Buechel Sr 
Background: Resurfacing-type total hip replacement (THR) has been successfully developed over the past 50 years through collaborative efforts between engineers and surgeons. Much of the development was pursued by indi...
关键词：Resurfacing Total Hip Replacement 
Macrophage-derived exosomes modulate wear particle-induced osteolysis via miR-3470b targeting TAB3/NF-κB signaling被引量：5
《Bioactive Materials》2023年第8期181-193,共13页Baiqi Pan Ziji Zhang Xiaoyu Wu Guoyan Xian Xuantao Hu Minghui Gu Linli Zheng Xiang Li Lingli Long Weishen Chen Puyi Sheng 
supported by the National Natural Science Foundation of China[grant numbers 82172405,81972050,81802179].
Aseptic prosthesis loosening(APL)is one of the most prevalent complications associated with arthroplasty.The main cause is the periprosthetic osteolysis induced by wear particles.However,the specific mechanisms of cro...
关键词：Aseptic prothesis loosening EXOSOME Non-coding RNA MACROPHAGE Inflammatory osteolysis 
Buechel-Pappas Total Ankle Replacement: Use of Highly Cross-Linked Polyethylene Meniscal Bearings over a 13 - 15 Year Interval
《Open Journal of Orthopedics》2023年第8期321-327,共7页Frederick F. Buechel Michael J. Pappas 
Background: The Buechel-Pappas (BP) meniscal bearing total ankle replace-ment was initially developed as a “shallow-sulcus” talar component device using cobalt-chromium-molybdenum alloy, in 1978, and later, modified...
关键词：Cementless Total Ankle Replacement Meniscal Ankle Replacement OSTEOLYSIS Bone Graft of Cysts 
Small extracellular vesicles derived from hypoxic preconditioned dental pulp stem cells ameliorate inflammatory osteolysis by modulating macrophage polarization and osteoclastogenesis被引量：6
《Bioactive Materials》2023年第4期326-342,共17页Jun Tian Weiyang Chen Yuhua Xiong Qianer Li Siyi Kong Mengjie Li Chunfeng Pang Yu Qiu Zhezhen Xu Qimei Gong Xi Wei 
This work was supported by National Natural Science Foundation of China(No.81870750,81970925,81900994);the Guangdong Financial Fund for High-Caliber Hospital Construction(174-2018-XMZC-0001-03-0125/D-08).
Extensive macrophage inflammatory responses and osteoclast formation are predominant during inflammatory or infective osteolysis.Mesenchymal stem cell(MSC)-derived small extracellular vesicles(MSC-sEV)have been shown ...
关键词：Dental pulp stem cells Small extracellular vesicles Macrophage OSTEOCLAST Inflammatory osteolysis 
Propionate and butyrate attenuate macrophage pyroptosis and osteoclastogenesis induced by CoCrMo alloy particles
《Military Medical Research》2023年第2期191-206,共16页Yang-Lin Wu Chen-Hui Zhang Yun Teng Ying Pan Nai-Cheng Liu Pei-Xin Liu Xu Zhu Xin-Lin Su Jun Lin 
supported by the National Natural Science Foundation of China(81871789,81802200,82172387);the Natural Science Foundation of Jiangsu Province(BK20180052);the Gusu Health Talents Program(GSWS2020023)。
Background:Wear particles-induced osteolysis is a major long-term complication after total joint arthroplasty.Up to now,there is no effective treatment for wear particles-induced osteolysis except for the revision sur...
关键词：NLRP3 inflammasome PYROPTOSIS Short chain fatty acids OSTEOLYSIS OSTEOCLAST 
Systemic IL-27 administration prevents abscess formation and osteolysis via local neutrophil recruitment and activation
《Bone Research》2022年第4期826-837,共12页Yugo Morita Motoo Saito Javier Rangel-Moreno Anthony M.Franchini John R.Owen John C.Martinez John L.Daiss Karen L.de Mesy Bentley Stephen L.Kates Edward M.Schwarz Gowrishankar Muthukrishnan 
supported by an NIH NIAMS P30 AR069655 pilot grant (G.M.) with additional support from NIH NIAID R21 AI69736 (G.M.);NIH NIAMS P50 AR072000(E.M.S.);P30 AR069655 (E.M.S.);the AO Trauma Clinical Priority Program (E.M.S.,S.L.K.);internal funds of the Department of Medicine and R01A111914 (J.R.M.)。
Interleukin-27 is a pleiotropic cytokine whose functions during bacterial infections remain controversial,and its role in patients with S.aureus osteomyelitis is unknown.To address this knowledge gap,we completed a cl...
关键词：ABSCESS protective IMMUNITY 
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