TETRAMETHYLPYRAZINE

作品数：58被引量：265H指数：9
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相关机构：中南大学齐鲁工业大学天津科技大学沈阳华泰药物研究所更多>>
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Tetramethylpyrazine and paeoniflorin combination(TMP-PF)inhibits angiogenesis in atherosclerosis via miR-126/VEGF/VEGFR2 signaling pathway被引量：1
《Journal of Future Foods》2024年第3期280-287,共8页Yahui Yuan Rong Yuan Qiqi Xin Yu Miao Ying Chen Rui Gao Weihong Cong 
supported by the National Natural Science Foundation of China(82004193);CACMS Innovation Fund(CI 2021A00914);the Fundamental Research Funds for the Central Public Welfare Research Institutes(ZZ14-YQ-007).
Angiogenesis in atherosclerosis(AS)promotes plaque destabilization.miR-126 has a significant role in angiogenesis.Tetramethylpyrazine(TMP)and paeoniflorin(PF)have anti-atherosclerotic effects.However,the miR-126-relat...
关键词：ATHEROSCLEROSIS ANGIOGENESIS TETRAMETHYLPYRAZINE PAEONIFLORIN miR-126/VEGF/VEGFR2 signaling pathway 
Medium-and long-term efficacy of ligustrazine plus conventional medication on ischemic stroke: a systematic review and meta-analysis被引量：6
《Journal of Traditional Chinese Medicine》2013年第6期715-720,共6页Xiaojia Ni Shaonan Liu Xinfeng Guo 
Supported by Joint Special Project of Guangdong Provincial Department of Science and Technology-Guangdong Provincial Academy of Chinese Medical Sciences:Construction and Application of Evidence-Based Knowledge Management System for Traditional Chinese Medicine(No.2012A032500009)
OBJECTIVE： To evaluate the medium- to long-term efficacy of ligustrazine plus conventional medicine treating ischemic stroke. METHODS： Randomized controlled trials （RCTs） testing ligustrazine in the treatment of a...
关键词：TETRAMETHYLPYRAZINE STROKE Time Sec-ondary prevention Review META-ANALYSIS 
Tetramethylpyrazine suppresses HIF-1α,TNF-α,and activated caspase-3 expression in middle cerebral artery occlusion-induced brain ischemia in rats被引量：30
《Acta Pharmacologica Sinica》2007年第3期327-333,共7页Yi CHANG George HSIAO Seu-hwa CHEN Yi-cheng CHEN Jiing-han LIN Kuang-hung LIN Duen-suey CHOU Joen-rong SHEU 
Project supported by grants from the Topnotch Stroke Research Center,Taipei Medical University;the Shin Kong Wu HoSu Memorial Hospital(SKH-TMU-94-07);the Committee on Chinese Medicine and Pharmacy(CCMP 94-RD-031).
Aim： To examine the detailed mechanisms underlying the inhibitory effect of tetramethylpyrazine （TMPZ） in inflammatory and apoptotic responses induced by middle cerebral artery occlusion （MCAO） in rats. Methods：...
关键词：TETRAMETHYLPYRAZINE middle cerebral artery occlusion HIF-1Α CASPASE-3 TNF-Α thiobarbituric acid-reactive substance 
PROTECTIVE EFFECT OF TETRAMETHYLPYRAZINE ON LEARNING AND MEMORY FUNCTION IN D-GALACTOSE-LESIONED MICE被引量：19
《Chinese Medical Sciences Journal》2004年第3期180-184,共5页ChunZhan Shi-zhenWang Ping-pingZuo XuCui JiongCai 
To explore the protective effect of tetramethylpyrazine (TMP) on the learning and memory function in D-galactose (D-gal)-lesioned mice. Methods C57BL/6 mice were injected (s.c.) 2% D-gal for 40 days (100 mg·kg-1·d-1...
关键词：TETRAMETHYLPYRAZINE D-GALACTOSE Alzheimer's disease cholinergic system N-methyl-D-aspartate receptor 
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