PAEONIFLORIN

作品数：53被引量：326H指数：11
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相关领域：医药卫生更多>>
相关作者：高萌杜英峰赵敏敏许慧君王春英更多>>
相关机构：河北医科大学北京大学中国医科大学华中科技大学更多>>
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相关基金：国家自然科学基金霍英东教育基金河北省自然科学基金上海市自然科学基金更多>>
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Tetramethylpyrazine and paeoniflorin combination(TMP-PF)alleviates atherosclerosis progress by reducing hyperlipemia and inhibiting plaque angiogenesis via the NR4A1/VEGFR2 pathway
《Food Science and Human Wellness》2024年第5期2642-2652,共11页Rong Yuan Qiqi Xin Weili Shi Yu Miao Zhengchuan Zhu Yahui Yuan Ying Chen Xiaoning Chen Sean Xiao Leng Keji Chen Weihong Cong 
supported by Fundamental Research Funds for the Central Public Welfare Research Institutes(ZZ11-061,ZZ14-YQ-007);the National Natural Science Foundation of China(82004193);CACMS Innovation Fund(CI 2021A00914);Irma and Paul Milstein Program for Senior Health of Milstein Medical Asian American Partnership Foundation。
Atherosclerosis remains a great threat to human health worldwide.Previous studies found that tetramethylpyrazine(TMP)and paeonifl orin(PF)combination(TMP-PF)exerts anti-atherosclerotic effects in vitro.However,whether...
关键词：ATHEROSCLEROSIS HYPERLIPEMIA ANGIOGENESIS Plaque stability Chinese medicine TETRAMETHYLPYRAZINE PAEONIFLORIN 
Tetramethylpyrazine and paeoniflorin combination(TMP-PF)inhibits angiogenesis in atherosclerosis via miR-126/VEGF/VEGFR2 signaling pathway被引量：1
《Journal of Future Foods》2024年第3期280-287,共8页Yahui Yuan Rong Yuan Qiqi Xin Yu Miao Ying Chen Rui Gao Weihong Cong 
supported by the National Natural Science Foundation of China(82004193);CACMS Innovation Fund(CI 2021A00914);the Fundamental Research Funds for the Central Public Welfare Research Institutes(ZZ14-YQ-007).
Angiogenesis in atherosclerosis(AS)promotes plaque destabilization.miR-126 has a significant role in angiogenesis.Tetramethylpyrazine(TMP)and paeoniflorin(PF)have anti-atherosclerotic effects.However,the miR-126-relat...
关键词：ATHEROSCLEROSIS ANGIOGENESIS TETRAMETHYLPYRAZINE PAEONIFLORIN miR-126/VEGF/VEGFR2 signaling pathway 
Paeoniflorin ameliorates chronic colitis via the DR3 signaling pathway in group 3 innate lymphoid cells
《Journal of Pharmaceutical Analysis》2024年第6期889-901,共13页Shaowei Huang Xueqian Xie Bo Xu Zengfeng Pan Junjie Liang Meiling Zhang Simin Pan Xiaojing Wang Meng Zhao Qing Wang Jinyan Chen Yanyang Li Lian Zhou Xia Luo 
supported by the National Natural Science Foundation of China(Grant No.:82074092),Natural Science Foundation of Guangdong Province,China(Grant No.:2021A1515012219);Guangzhou University of Chinese Medicine“Double First-Class”and High-level University Discipline Collaborative Innovation Team Project,China(Grant No.:2021xk81) and Graduate Research Innovation Project of Guangzhou University of Chinese Medicine,China.
Inhibiting the death receptor 3(DR3)signaling pathway in group 3 innate lymphoid cells(ILC3s)presents a promising approach for promoting mucosal repair in individuals with ulcerative colitis(UC).Paeoniflorin,a promine...
关键词：PAEONIFLORIN Ulcerative colitis Intestinal mucosal barrier DR3 signaling pathway Group 3 innate lymphoid cells 
Paeoniflorin alleviates depression by inhibiting the activation of NLRP3 inflammasome via promoting mitochondrial autophagy被引量：1
《Chinese Journal of Natural Medicines》2024年第6期515-529,共15页SU Lili GUO Pengli GUO Xiangjuan HE Zhongmei ZHAO Yan ZONG Ying LI Jianming CHEN Weijia DU Rui 
supported by the Jilin Science&Technology Development Plan(Nos.20210204001YY,20200404090YY);Jilin Province aid Project for Xinjiang Uygur Autonomous Region(No.0207-202020043).
Depression ranks among the most common neuropsychiatric disorders globally.Current studies examining the roles of inflammation and mitochondrial autophagy in the antidepressant efficacy of paeoniflorin(PF)are sparse.T...
关键词：PAEONIFLORIN DEPRESSION AUTOPHAGY NLRP3 inflammasome 
Paeoniflorin,the Main Monomer Component of Paeonia lactiflora,Exhibits Anti-inflammatory Properties in Osteoarthritis Synovial Inflammation被引量：2
《Chinese Journal of Integrative Medicine》2024年第5期433-442,共10页CHEN Pu ZHOU Jun RUAN An-min MA Yu-feng WANG Qing-fu 
Supported by the National Natural Science Foundation of China (No.81373662 and No.81874475);Capacity Building Project of Chinese and Western Medicine Clinical Collaboration on Major Difficult Disease (No.201803190106)。
Objective:To explore the mechanism of paeoniflorin(PF)on osteoarthritis(OA)synovial inflammation from network pharmacology to experimental pharmacology.Methods:Targets of OA were constructed by detecting the database ...
关键词：PAEONIFLORIN OSTEOARTHRITIS synovial inflammation tumor necrosis factor-α network pharmacology Paeonia lactiflora 
Changes in the root system of the herbaceous peony and soil properties under different years of continuous planting and replanting被引量：4
《Horticultural Plant Journal》2023年第4期801-810,共10页Anqi Xie Limin Sun Dongliang Zhang Yang Li Zemiao Liu Xue Li Xia Sun 
supported by grants from the National Natural Science Foundation of China(Grant No.31670663).
The herbaceous peony(Paeonia lactiflora Pall.)has high ornamental value.Replanting problems occur when seedlings are replanted into previous holes.We studied the root system and soil environment of the'Dongjingnvlang'...
关键词：Herbaceous peony Replanting problems Continuous planting Soil environment Phenolic acids PAEONIFLORIN 
Study on Preparation Process and Quality Standard of Tianlu Tongluo Granules被引量：1
《Agricultural Biotechnology》2022年第6期149-154,共6页Diya PAN Xiangling QU Yuling LUO Xunrong ZHOU 
Supported by Project of Guiyang Science and Technology Bureau(ZKHT[2020]-18-4).
[Objectives]This study was conducted to optimize the preparation process of Tianlu Tongluo Granules and establish its quality standard.[Methods]Tianlu Tongluo Granules was prepared by an orthogonal test.TLC was used t...
关键词：Tianlu Tongluo Granules PAEONIFLORIN Preparation process Quality standard TLC HPLC 
Study on Quality Standard of Lujing Yiqi Shengxue Pills
《Agricultural Biotechnology》2022年第3期93-98,153,共7页Lida CHEN Xianmei XU Yuchuan LI Yuanfeng YANG Yuling LUO 
Supported by Guiyang Science and Technology Planning Project(ZKHT[2020]-18-4)。
[Objectives]This study was conducted to establish the quality standard for Lujing Yiqi Shengxue Pills to provide a basis for its quality control.[Methods]According to the quality requirements in the 2020 edition of Ch...
关键词：Lujing Yiqi Shengxue pills Quality evaluation Thin layer chromatography PAEONIFLORIN Content determination 
Paeoniflorin ameliorates ischemic injury in rat brain via inhibiting cytochrome c/caspase3/HDAC4 pathway被引量：5
《Acta Pharmacologica Sinica》2022年第2期273-284,共12页Yi-fei Liu Lei Zhang Qi Wu Lin-yin Feng 
This study was supported by grants from the National Science&Technology Major Project“Key New Drug Creation and Manufacturing Program”,China(2018ZX09711002-003-013);the Scientific Innovation Project of the Chinese Academy of Sciences(XDA12040304 and XDA12040216);This project was supported by the Shanghai Committee of Science and Technology,China(18DZ2290200).
Paeoniflorin (PF), a bioactive monoterpene glucoside, has shown a variety of pharmacological effects such as anti-inflammation and autophagy modulation etc. In this study, we investigated whether and how PF exerted a ...
关键词：ischemic brain injury PAEONIFLORIN MCAO HDAC4 cytochrome c APOPTOSIS 
Paeoniflorin inhibits lipopolysaccharide-induced inflammation in LO2 cells by regulating RhoA/NLRP3 pathway
《Journal of Traditional Chinese Medical Sciences》2021年第2期161-165,共5页Haixia Liu Fafeng Cheng Feifei Tang Yifang Wang Shuling Liu Xueqian Wang 
This work was supported by the National Natural Science Foundation of China(81774122);the Chinese Major Scientific and Technological Special Project for Major New Drug Creation(2019ZX09301-173).
Background:Inflammation is an essential component of liver diseases.Paeoniflorin(PF),a monoterpenoid component derived from peony root(Paeonia lactiflora Pall.),has anti-inflammatory,immunoregulatory,and hepatoprotect...
关键词：PAEONIFLORIN LIPOPOLYSACCHARIDE INFLAMMATION RHOA NLRP3 inflammasome 
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