supported by the National Key Research and Development Project (No.2019YFC1005203);the National Natural Science Foundation of China (No.81771608&82120108011);Major Project of Shanghai Municipal Education Commission’s Scientific Research and Innovation Plan (No.2021-01-07-00-07-E00144);Outstanding Academic Leaders Program of Shanghai Municipal Science and Technology Commission (No.18XD1405100);“Shuguang Program” by Shanghai Municipal Education Commission (No.17SG36);the Program for Professor of Special Appointment (Eastern Scholar) at Shanghai Institutions of Higher Learning。