先天免疫

作品数:458被引量:1011H指数:13
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相关领域:农业科学医药卫生更多>>
相关作者:王金星赵小凡许平震曲鹏沈秀丽更多>>
相关机构:山东大学上海海洋大学南京师范大学南昌大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划国家教育部博士点基金更多>>
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  • 期刊=Cell Researchx
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TREM2 enables amyloid β clearance by microglia被引量:3
《Cell Research》2015年第5期535-536,共2页Serge Rivest 
In a recent paper published in Cell, Wang et al. report that deficiency of triggering receptor expressed on myeloid cells 2 (TREM2) augments amyloid β accumulation and neuronal loss in a mouse model of Alzheimer's...
关键词:小胶质细胞 粉样 阿尔茨海默氏病 细胞表达 小鼠模型 先天免疫 神经元 累积和 
F^hoGTPases- NODes for effector-triggered immunity in animals
《Cell Research》2013年第8期980-981,共2页Lynda M Stuart Laurent Boyer 
A recent study published in Nature by Keestra and colleagues addresses how the immune system detects the pathogenic potential of microbes and provides evidence that one strategy involves NOD1, which monitors the activ...
关键词:免疫动物 致病微生物 触发 节点 检测系统 病原微生物 免疫系统 先天免疫 
NLRC5: a NOD-like receptor protein with many faces in immune regulation被引量:7
《Cell Research》2012年第7期1099-1101,共3页Yue Zhao Feng Shao 
Intracellular NOD-like receptor (NLR) proteins are believed to play important roles in innate immune detection or immune regulation, but only a few NLR proteins are functionally defined. Recent intensive studies, la...
关键词:受体蛋白 免疫调节 NOD 先天免疫 信号调节 免疫检测 免疫反应 生理功能 
F-box protein AFB4 plays a crucial role in plant growth, development and innate immunity被引量:9
《Cell Research》2012年第4期777-781,共5页Zhubing Hu Mehmet Ali Kegeli Maria Piisila Jing Li Mantas Survila Pekka Heino Gtinter Brade E Tapio Palva 
Dear Editor, Auxin-signaling F-box protein 4 (AFB4) encoded by At4g24390 shares a significant sequence similarity to auxin receptor TIR1. In this study, we used a combination of physiological, molecular, and geneti...
关键词:植物生长 先天免疫 蛋白 T-DNA插入 发育 等位基因 序列相似性 遗传方式 
TLR-induced activation of Btk- Role for endosomal MHC class II molecules revealed
《Cell Research》2011年第7期998-1001,共4页Joan Ni Gabhann Caroline A Jefferies 
MHC molecules have been shown to play key roles in the immune system including regulating T-cell repertoire development through the process of positive and negative selection. MHC molecules also function to bridge the...
关键词:分子表达 MHC TLR 激活 诱导 免疫系统 选择过程 先天免疫 
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