Ras gene mutation has been observed in more than 30%of cancers,and 90%of pancreatic,lung and colon cancers.Ras proteins(K-Ras,H-Ras,N-Ras)act as molecular switches which are activated by binding to GTP.They play a rol...
Supported by Liaoning Medical "Principal Fund" special fund clinical construction,No.XZJJ20130214;Liaoning Provincial Science and Technology Department of Science and Technology Program,No.2013225305
AIM: To investigate the targeted inhibition of proliferation and migration of SW620 human colon cancer cells by upregulating mi RNA-145(mi R-145).METHODS: Forty-five samples of colon cancer tissues and 45 normal contr...