the Ministry of Science and Technology of China(Nos.2021YFA1102000,2021YFC2700300,2019YFA0110000,and 2018YFA0108900);the National Natural Science Foundation of China(NSFC)(Nos.31721003,32022024,32270850,32100633,31871486,32070652,and 81630035);the Science and Technology Commission of Shanghai Municipality(Nos.19JC1415300 and 21JC1405500).
Human pluripotent stem cells provide an inexhaustible model to study human embryogenesis in vitro.Recent studies have provided diverse models to generate human blastoids by self-organization of different pluripotent s...
This work was supported by the National Natural Science Foundation of China (81472468, 81672614, 81622036, 81490750, 81230060, 81442009, 81472467, 81272894, 81372816 and 81372819), the Science Foundation of Guangdong Province (2016A030306023, 2014A030313094, $2012030006287, 2014A030313175), the National Basic Research Program of China (973 Projects; SQ2015CB050449), Guangzhou Science Technology and Innovation Commission (201508020008, 201508020249), Guangdong Science and Technology Department (2015B050501004), Translational Medicine Public Plat- form of Guangdong Province (4202037), Guangdong Depart- ment of Science & Technology Translational Medicine Center (2011A080300002), Sun Yat-Sen University (16ykpy07), Breast Cancer Alliance Exceptional Project Grant and US National Cancer Institute RO1 CA211694.
The origin of tumor-infiltrating Tregs, critical mediators of tumor immunosuppression, is unclear. Here, we show that tumor-infiltrating naive CD4+ T cells and Tregs in human breast cancer have overlapping TCR repert...
The research was partly completed when WANG Zhi-ren was in Institute of Mental Health of Peking University as a Ph.D candiadate, now he works in Beijing Hui-Long-Guan Hospital. This work was supported by grants from the National Basic Research Program of China (973 Program: 2007BC512307), the Capital Medical Development Fund (2009-3148), the National Natural Science Foundation of China (81000579) and the Beijing Municipal Science & Technology Commission (No. D0906001040191).
Background Patients with schizophrenia have prominent abnormality in information processing that can be observed by measures of prepulse inhibition (PPI) of acoustic startle reflex and PPI deficits have been conside...