NIH3T3

作品数:137被引量:279H指数:7
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相关领域:医药卫生生物学更多>>
相关作者:肖冰张梅英张巧秦英杨葳更多>>
相关机构:中国医科大学南方医科大学南方医院中国医学科学院北京协和医学院郑州大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划广东省自然科学基金更多>>
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Senescence-like changes induced by expression of p21^(Waf1/Cipl)in NIH3T3 cell line被引量:9
《Cell Research》2002年第4期229-233,共5页XI CHEN WEI ZHANG YUN FEI GAO XIAO QIN SU ZHONG HE ZHAI 
We thank Dr. Gordon Peters of Imperial CancerResearch Fund for providing p21(Waf1/Cip1) cDNA,Dr. Hong-Bing Shu of National Jewish Medica1and Reearch Center for pRetro-on-Bax and 293-10A1 packaging line. We also thank Drs. WeiTAO and Zhi Gang LU
P21Waf1/Cip1 is a potent cyclin-dependent kinase inhibitor. As a downstream mediator of p53, p21Waf1/Cip1 involves in cell cycle arrest, differentiation and apoptosis. Previous studies in human cells provided evidence...
关键词:p21Wafl1/Cip1 SENESCENCE inducible expression cell cycle arrest. 
Senescence—like changes induced by expression of p21^Waf1/Cip1 in NIH3T3 cell line被引量:3
《Cell Research》2002年第3期229-233,共5页X1CHEN WEIZHANG  
国家重点基础研究发展计划(973计划)
P21Waf1/Cip1 is a potent cyclin-dependent kinase inhibitor. As a downstream mediator of p53, p21Waf1/Cip1 involves in cell cycle arrest, differentiation and apoptosis. Previous studies in human cells provided evidence...
关键词:P21WAF1/CIP1 SENESCENCE inducible expression cell cycle arrest 
Preliminary evidence that overexpression of nuclearfactor for IL6 expression (NF-IL6) in NIH3T3 cells may berelated to malignant transformation
《Cell Research》1994年第2期191-200,共10页ZHU MINSHENG DINGGAN LIU SHIZUO AKIRA ZAIPING LI.(Shanghai Institute of Biochemistry, Academic Sinica,Shanghai 200031, China)(Institute of Molecular and Cellular Biology, Osaka University, Japan) 
NF-IL6 is a member of c/EBP family and has multiple functions in regulation of cellular gene expression. We have constructed NF-IL6 expression plasmids and trans fected the NIH3T3 cells with them. The sense NF-IL6 tra...
关键词:NF-IL6 NIH3T3 tumorigenicity 
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