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On-chip dielectrophoretic single-cell manipulation
《Microsystems & Nanoengineering》2024年第4期87-114,共28页Zuyuan Tian Xihua Wang Jie Chen 
by funding support from the Natural Sciences and Engineering Research Council(NSERC)and MITACS;supported by the China Scholarship Council(CSC)No.202006290002.
Bioanalysis at a single-cell level has yielded unparalleled insight into the heterogeneity of complex biological samples.Combined with Lab-on-a-Chip concepts,various simultaneous and high-frequency techniques and micr...
关键词：MANIPULATION utilize DIELECTRIC 
Nanofabricated high turn-density spiral coils for on-chip electromagneto-optical conversion
《Microsystems & Nanoengineering》2024年第2期181-192,共12页Ilhan Bok Alireza Ashtiani Yash Gokhale Jack Phillips Tianxiang Zhu Aviad Hai 
supported by the National Institute of Neurological Disorders and Stroke and the Office of the Director’s Common Fund at the National Institutes of Health(grant DP2NS122605 to A.H.);the National Institute of Biomedical Imaging and Bioengineering(grant K01EB027184 to A.H.);This material is also based upon research supported by the US Office of Naval Research under PANTHER award numbers N00014-23-1-2006 and N00014-22-1-2371 to A.H.through Dr.Timothy Bentley.
Circuit-integrated electromagnets are fundamental building blocks for on-chip signal transduction,modulation,and tunability,with specific applications in environmental and biomedical micromagnetometry.A primary challe...
关键词：utilize retaining HIGH 
Multiplexed fluorescence and scatter detection with single cell resolution using on-chip fiber optics for droplet microfluidic applications被引量：2
《Microsystems & Nanoengineering》2024年第2期207-218,共12页Preksha Gupta Ambili Mohan Apurv Mishra Atindra Nair Neeladri Chowdhury Dhanush Balekai Kavyashree Rai Anil Prabhakar Taslimarif Saiyed 
support of Biotechnology Industry Research Council(BIRAC),Biomedical Device and Technology Development(BDTD)grant by Department of Science and Technology(DST)and Scheme for Transformational and advanced Research in Sciences(STARS)grant by Ministry of Human Resource Development(MHRD),India for funding support.
Droplet microfluidics has emerged as a critical component of several high-throughput single-cell analysis techniques in biomedical research and diagnostics.Despite significant progress in the development of individual...
关键词：SCATTER enable RESOLUTION 
Integration of multiple flexible electrodes for realtime detection of barrier formation with spatial resolution in a gut-on-chip system
《Microsystems & Nanoengineering》2024年第1期105-114,共10页Mara Lucchetti Gabriel Werr Sofia Johansson Laurent Barbe Léa Grandmougin Paul Wilmes Maria Tenje 
funding from the European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie(grant agreement No.812954);the European Research Council(ERC)under the European Union’s Horizon 2020 research and innovation program(grant agreement No.757444 and grant agreement No.863664);funded by the Swedish Research Council(2019-00207)as a national research infrastructure;funding provided by Uppsala University.
In healthy individuals,the intestinal epithelium forms a tight barrier to prevent gut bacteria from reaching blood circulation.To study the effect of probiotics,dietary compounds and drugs on gut barrier formation and...
关键词：BARRIER SYSTEM MULTIPLE 
Measurement of oxygen consumption rates of human renal proximal tubule cells in an array of organ-on-chip devices to monitor drug-induced metabolic shifts
《Microsystems & Nanoengineering》2022年第5期149-160,共12页Samuel H.Kann Erin M.Shaughnessey Jonathan R.Coppeta Hesham Azizgolshani Brett CIsenberg Else M.Vedula Xin Zhang Joseph L.Charest 
This material is based uponwork supported by the National Science Foundation under Grant nos.1804845 and 1804787.
Measurement of cell metabolism in moderate-throughput to high-throughput organ-on-chip(OOC)systems would expand the range of data collected for studying drug effects or disease in physiologically relevant tissue model...
关键词：METABOLISM culture OCR 
Deposition chamber technology as building blocks for a standardized brain-on-chip framework
《Microsystems & Nanoengineering》2022年第4期151-164,共14页B.G C Maisonneuve L.Libralesso L.Miny A.Batut J.Rontard M.Gleyzes B.Boudra J.Viera D.Debis F.Larramendy V.Jost T.Honegger 
the European Research Council(ERC)under the European Union’s Horizon 2020 research and innovation program(grant agreement num.714291).
The in vitro modeling of human brain connectomes is key to exploring the structure-function relationship of the central nervous system.Elucidating this intricate relationship will allow better studying of the patholog...
关键词：ARCHITECTURES OVERCOME hence 
Enhancing sensitivity in atomic force microscopy for planar tip-on-chip probes
《Microsystems & Nanoengineering》2022年第3期39-49,共11页H.Tung Ciftci Michael Verhage Tamar Cromwijk Laurent Pham Van Bert Koopmans Kees Flipse Oleg Kurmosikov 
supported by NWO-TTW under project number 14715,by the French PIA under project number ANR-15-DEX-04-LUECAP-MAT,by the"FEDER-FSE Lorraine et Massif Vosges 2014-2020",and by the region Grand Est under the DESOMIN project。
We present a new approach to tuning-fork-based atomic force microscopy for utilizing advanced"tip-on-chip"probes with high sensitivity and broad compatibility.Usually,such chip-like probes with a size reaching 2×2 mm...
关键词：tuning ATOMIC utilizing 
Rapid switching and durable on-chip spark-cavitation-bubble cell sorter
《Microsystems & Nanoengineering》2022年第3期253-262,共10页Zeheng Jiao Yong Han Jingjing Zhao Zixi Chao Attila Tarmok Zheng You 
supported by the fund forthe Joint Project of Bejing(Bejing Municipal Commission of Education);the National Natural Science of China(Grant Number:61727813)。
Precise and high-speed sorting of individual target cells from heterogeneous populations plays an imperative role in cell research.Although the conventional fluorescence-activated cell sorter(FACs)is capable of rapid ...
关键词：SORTING BUBBLE CAVITATION 
Self-assembled microtubular electrodes for on-chip low-voltage electrophoretic manipulation of charged particles and macromolecules
《Microsystems & Nanoengineering》2022年第1期341-352,共12页Apratim Khandelwal Nagendra Athreya Michael Q.Tu Lukas L.Janavicius Zhendong Yang Olgica Milenkovic Jean-Pierre Leburton Charles M.Schroeder Xiuling Li 
This work was supported in part by the SemiSynBio grant:SRC 2018-SB-2839;NSF CCF 18-07526。
On-chip manipulation of charged particles using electrophoresis or electroosmosis is widely used for many applications,including optofluidic sensing,bioanalysis and macromolecular data storage.We hereby demonstrate a ...
关键词：ELECTRODES cylindrical planar 
On-chip multiplexed single-cell patterning and controllable intracellular delivery被引量：2
《Microsystems & Nanoengineering》2020年第1期1222-1232,共11页Zaizai Dong Yanli Jiao Bingteng Xie Yongcun Hao Pan Wang Yuanyuan Liu Junfeng Shi Chandani Chitrakar Stephen Black Yu-Chieh Wang LJames Lee Mo Li Yubo Fan Lingqian Chang 
L.C.acknowledges the funding from INSCA at the Beijing Advanced Innovation Center for Biomedical Engineering and Beihang University;start-up funding was received from UNT.
Conventional electroporation approaches show limitations in the delivery of macromolecules in vitro and in vivo.These limitations include low efficiency,noticeable cell damage and nonuniform delivery of cells.Here,we ...
关键词：inhibited VACUUM LIMITATIONS 
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