PARKINSON

作品数:289被引量:1261H指数:11
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相关领域:医药卫生生物学更多>>
相关作者:陈生弟王刚刘振国王坚马淑芳更多>>
相关机构:上海交通大学医学院附属瑞金医院首都医科大学首都医科大学宣武医院中国医科大学附属第一医院更多>>
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相关基金:国家自然科学基金中国博士后科学基金上海市科学技术委员会资助项目山东省自然科学基金更多>>
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Human stem cell-based cell replacement therapy for Parkinson’s disease:Enhancing the survival of postmitotic dopamine neuron grafts
《Neural Regeneration Research》2026年第2期689-690,共2页Tae Wan Kim 
supported by the DGIST start-up funds from the Ministry of Science and ICT(2024010330);a National Research Foundation of Korea(NRF)grant funded by the Korea Government(MSIT)(No.RS-2024-00351442)(to TWK).
Parkinson’s disease(PD)is the second most common neurodegenerative disorder.The progressive degeneration of dopamine(DA)producing neurons in the midbrain is the pathological hallmark,which leads to debilitating motor...
关键词:neuronal survival cell replacement therapy dopamine neurons human stem cells bradykinesiadrug treatmentssuch Parkinsons disease neurodegenerative disorderthe parkinson s disease pd 
Chinese guidelines on remote programming of deep brain stimulation for patients with Parkinson’s disease
《Chinese Medical Journal》2025年第3期261-263,共3页Fangang Meng Jie Zhang Wenbin Zhang Ling Chen Jianjun Wu Shanshan Mei Lijuan Wang Jianguo Zhang The Chinese Medical Association Neurosurgery Branch of Functional Neurosurgery Group The Chinese Medical Association Neurology Branch of Parkinson’s Disease,Movement Disorders Group The Chinese Physician Association Neurosurgeon Branch of Functional Neurosurgery Expert Committee The Chinese Physician Association Neurologist Branch of Parkinson’s Disease and Movement Disorders Professional Committee China Neuromodulation Union Society Whole-process Management of Neuromodulation and Chinese Expert Committee on Deep Brain Stimulation for Parkinson’s Disease 
National Key Research and Development Program of China(Nos.2022YFC2405100 and 2021YFC2401200);National Natural Science Foundation of China(No.81830033);Key R&D Program of Jiangsu Science and Technology Project(No.BE2022049);Key Research and Development Program of Henan Province(No.241111310100)
Deep brain stimulation(DBS)is a neurosurgical procedure that allows targeted circuit-based neuromodulation;it is also a standard of care for Parkinson’s disease(PD).[1]Postoperative DBS programming is a crucial step ...
关键词:stimulation parameters neurosurgical procedure deep brain stimulation dbs release symptoms parkinson s disease which remote programming postoperative programming deep brain stimulation 
Essential tremor plus affects disease prognosis:A longitudinal study
《Chinese Medical Journal》2025年第1期117-119,共3页Runcheng He Mingqiang Li Xun Zhou Lanqing Liu Zhenhua Liu Qian Xu Jifeng Guo Xinxiang Yan Chunyu Wang Hainan Zhang Irene XYWu Beisha Tang Sheng Zeng Qiying Sun 
supported by grants from the National Natural Science Foundation of China(Nos.U20A20355,82171256,and 82202051);the Hunan Natural Science Foundation of China(No.2021SK53501).
To the Editor:Essential tremor(ET)is a common movement disorder with significant clinical heterogeneity.[1]Following the proposal of“ET-plus”,the cross-sectional investigation of ET has increased.However,the charact...
关键词:movement disorder annual incidence parkinson s disease etpd essential tremor longitudinal study clinical heterogeneity 
Liquid Subcutaneous Levodopa-Carbidopa ND0612 Effects on Motor Symptoms in Individuals with Parkinson’s Disease: A Systematic Review and Meta-Analysis
《Advances in Parkinson's Disease》2024年第2期9-25,共17页Paula Abola Mitchell Wolden Kristin Lefebvre 
Objective: In the manuscript titled “Liquid subcutaneous Levodopa-Carbidopa ND0612 effects on motor symptoms in individuals with Parkinson’s Disease: A systematic review and meta-analysis”, the objective was to con...
关键词:Parkinson’s Disease ND0612 Levodopa-Carbidopa Motor Symptoms Motor Complications UPDRS 
The involvement of Slc7a11/xCT related iron accumulation on acupuncture intervention in 6-OHDA-induced Parkinson rat
《Clinical Traditional Medicine and Pharmacology》2024年第4期34-43,共10页Lihong Li Wei Jin Jun Lu Zitong Xu Zhaoshun Lv Jianquan Yin Wenjie Cong 
supported by Natural Science Foundation of China(No.82104982);Zhejiang Funding of Traditional Chinese Medicine(GZY-ZJ-KJ-24016,GZY-ZJ-KJ-23017);Natural Science Foundation of Zhejiang province,China(No.LGD19H090005).
Background:Acupuncture plays a critical role for the treatment of patients with Parkinson’s disease(PD),which is characterized by ferroptosis of dopaminergic neurons.It has been found that acupuncture can reduce iron...
关键词:Parkinson’s disease RNA-SEQ Slc7a11/xCT ACUPUNCTURE 
帕金森病伴发抑郁症的影响因素及非药物干预研究进展
《军事护理》2024年第9期84-86,90,共4页刘瑞 柳琳 杨嘉伟 高永娥 曹孟娇 李春玉 沈玮 
山东省中医药科技发展计划项目(2019-0169)。
帕金森病(Parkinson’s disease,PD)又称震颤麻痹,是中老年人常见的慢性、不完全可逆的中枢神经系统变性疾病,临床表现包括一系列运动和非运动症状[1]。其中,帕金森病伴发抑郁症(Parkinson’s disease with depression,PDD)发病率约为31...
关键词:非运动症状 非药物干预 帕金森病伴发抑郁 震颤麻痹 PARKINSON 中老年人 
The QT interval in Parkinson′s disease:a systematic review
《Journal of Geriatric Cardiology》2024年第9期855-864,共10页Simon W Rabkin 
Background PD(PD)is associated with a twofold increase in the risk of death especially sudden death.A predisposing factor for cardiac sudden death is prolongation of the QT interval.This study evaluated the potential ...
关键词:QT QTC FOCUS 
中医药与miRNA在帕金森病线粒体功能障碍中的调控作用被引量:1
《中国中西医结合杂志》2024年第8期1004-1012,共9页张明悦 沈晓明 John Eailing 谢雁鸣 周怡 郭如月 卢瑾 宁允帆 周娇 郭惠平 孟明贤 郝诗楠 
国家自然科学基金青年基金项目(No.81303011);国家中医药管理局全国名老中医药专家传承工工作室建设项目(No.豫中医业函[2014]86号);河南省重点研发与推广专项(No.202102310166);河南省中医药科学研究专项课题(No.2019ZY1006)。
帕金森病(Parkinson'sdisease,PD)是全球第二大神经系统退行性疾病,多发于65岁以上人群,发病率约1.7%,并保持逐年攀升的态势^([1])。
关键词:线粒体功能障碍 帕金森病 中医药 神经系统退行性疾病 PARKINSON 调控作用 发病率 
澄清误区,不再惧“帕”
《家庭医药(快乐养生)》2024年第8期95-95,共1页谢勇 
帕金森病(Parkinson's Disease,PD)又称震颤麻痹,是一种常见的神经系统退行性疾病,主要因为多巴胺的神经递质减少而发病。目前,帕金森病在我国的发病率约为1.7%,全国患者已超过300万。然而,很多人对其了解不足,导致该病的治疗率很低。以...
关键词:帕金森病 震颤麻痹 神经递质 多巴胺 治疗率 神经系统退行性疾病 PARKINSON 
Effects of psychological nursing in Parkinson's related depression patients undergoing functional magnetic resonance imaging:A randomized controlled trial
《World Journal of Clinical Cases》2024年第17期3086-3093,共8页Xiao-Xia Zhang Xiao-Hui Zhang Yan-Chao Dong 
Supported by Qinhuangdao Science-Technology Support Projects of China,No.202101A141.
BACKGROUND Patients with Parkinson’s disease(PD)often experience depression,and some may require magnetic resonance imaging(MRI)for diagnosis,which can lead to MRI failure due to claustrophobia.AIM To explore the val...
关键词:Magnetic resonance imaging Psychological nursing Parkinson's disease DEPRESSION Claustrophobia 
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