supported by the National Natural Science Foundation of China(Grant No.81973243);the National Human Genetic Resources Center,National Research Institute for Family Planning。
1 Introduction The rapidly growing protein structure data is a valuable biological resource and has been a focus of research in the academic community.The abundance of 3D structure data also presents challenges for re...
supported by the National Key R&D Program of China(Grant Nos.2021YFF0704300 and 2020YFA0712400);the National Natural Science Foundation of China(Grant Nos.62072280,61771009,61932018,62072441,32241027,and T2225007);the open project of BGI-Shenzhen,Shenzhen 518000,China(Grant No.BGIRSZ20220005);the Natural Science Foundation of Ningxia Province,China(Grant No.2023AAC05036).
The release of AlphaFold2 has sparked a rapid expansion in protein model databases.Efficient protein structure retrieval is crucial for the analysis of structure models,while measuring the similarity between structure...
partly supported by National Natural Science Foundation of China (Nos. 82074155, 81874436, 81973773, China);“Shuguang Program” supported by Shanghai Education Development Foundation and Shanghai Municipal Education Commission (No. 18SG39, China);Program of Shanghai Academic/Technology Research Leader (No. 20XD1423500, China);Clinical Research Plan of SHDC (No. SHDC2020CR3089B, China);Shanghai Key Clinical Specialty Construction Project (No.shslczdzk01201, China);Shanghai Frontier Research Base of Disease and Syndrome Biology of inflammatory cancer transformation (No. 2021KJ03-12, China);Shanghai Sailing Program (No. 20YF1450200, China);Shanghai Collaborative Innovation Center of Industrial Transformation of Hospital TCM Preparation (China)
Nonalcoholic fatty liver disease(NAFLD)is characterized by excessive accumulation of hepatic lipids and metabolic stress-induced liver injury.There are currently no approved effective pharmacological treatments for NA...