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作品数：97被引量：108H指数：5
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相关机构：华北理工大学北京协和医学院北京化工大学中国药科大学更多>>
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A dual-protease-triggered chemiluminescent probe for precise tumor imaging
《Chinese Chemical Letters》2025年第2期274-278,共5页Zhihui Zhang Ru Sun Chong Bian Hongbo Wang Zhen Zhao Panpan Lv Jianzhong Lu Haixin Zhang Hulie Zeng Yuanyuan Chen Zhijuan Cao 
financial support by National Key R&D Program of China,MOST(No.2023YFC2510000);Shanghai Science and Technology(No.21N31900500);Shanghai Municipal Health Commission Project(No.202140016);Training Program for Outstanding Young Medical and Pharmaceutical Talents of Minhang District Health System(No.mwyjyx08);the Project of Basic Medicine funded by Fudan-Minhang Health Consortium(Nos.2021MHJC10 and 2023FM09)。
Imaging detection of interlinked dual proteases is imperative for precise tumor imaging,which remains challenging due to limited modification position of specific substrate and possible steric hindrance.Herein,we have...
关键词：Dual-protease imaging Tripeptide substrate Chemiluminescent Phenoxy-dioxetane scaffold Logic gates 
Design,Synthesis and Pharmacological Evaluation of Novel 4-Phenoxyquinoline Derivatives as VEGFR2 Kinase Inhibitors for Tumor Treatment
《Chemical Research in Chinese Universities》2025年第1期66-78,共13页JIANG Wei CHEN Jiayan WANG Haifeng XUE Aiqi ZHANG Xinyang GUAN Jichi WEI Lulu CAI Jianfeng HU Yong LIU Dan 
supported by the National Natural Science Foundation of China(Nos.52173128,51973091);the Scientific Research Fund of Liaoning Provincial Education Department,China(No.LQ2020021);the Natural Science Foundation of Jiangsu Province(Youth Foundation),China(No.BK20220784).
Vascular endothelial growth factor 2(VEGFR2)plays a vital role in regulating of tumor metastasis and angiogenesis,which has emerged as one of the effective targets for clinical tumor therapy.Herein,a series of novel f...
关键词：ar endothelial growth factor 2(VEGFR2) 4-Phenoxyquinoline Inhibitor ANTI-TUMOR ANGIOGENESIS 
Bioaugmentation of a novel bacterial consortium in cotton-planted soil for lambda-cyhalothrin degradation
《Pedosphere》2024年第6期1100-1110,共11页Samina ANWAR Anusha LIAQAT Asma MUNIR Muhammad F.ASHRAF Samina IQBAL 
supported by the Higher Education Commission(HEC),Pakistan(No.NRPU 9570)。
Extensive use of lambda-cyhalothrin(LC)for agricultural and domestic pest control leads to the accumulation of its residues in soil and water,which poses a serious threat to the environment.Remediation of LC at the po...
关键词：BIOREMEDIATION HPLC analysis pesticide 3-phenoxybenzoic acid point source of contamination PYRETHROIDS Taguchi design of experiment 
新型白念珠菌生物被膜抑制剂IMB-H12的活性和作用机制研究
《药学学报》2024年第4期948-956,共9页李丹 朱小红 卞聪 魏元娟 时文静 李妍 袁丽杰 
国家自然科学基金资助项目(32141003);中国医学科学院医学与健康科技创新工程(2021-12M-1-070);河北省自然科学基金资助项目(H2021209027).
白念珠菌是真菌感染疾病中的主要病原菌,生物被膜的形成是白念珠菌毒力特征,同时也是重要的耐药机制,开发具有生物被膜抑制活性的抗真菌药物具有重要的意义。本研究对前期获得的新型的具有生物被膜抑制活性的化合物1-(cyclopentylamino)...
关键词：白念珠菌 生物被膜 1-(cyclopentylamino)-3-(4-(2 4 4-trimethylpentan-2-yl)phenoxy)propan-2-ol 黏附 菌丝 
A metal-free coordination–insertion ring-opening polymerization of tetrahydrofuran by the central metalloid bis(pentafluorophenyl)(phenoxy)borane
《Chinese Chemical Letters》2024年第3期419-422,共4页Cheng Wu Yixuan Liu Chunsheng Xiao Chenyang Hu Xuan Pang Xuesi Chen 
funded by the National Key R&D Program of China(No.2021YFA1501700);the Science and Technology Development Plan of Jilin Province(Nos.20230101042JC,20210201059GX);the National Natural Science Foundation of China,Basic Science Center Program(No.51988102);the National Natural Science Foundation of China(Nos.52203017,52073272 and 22293062);Bureau of International Cooperation Chinese Academy of Sciences(No.029GJHZ2023017MI)。
A new strategy for the metal-free coordination–insertion ring-opening polymerization of tetrahydrofuran by the central metalloid Boron has been first identified.Bis(pentafluorophenyl)(phenoxy)borane was used as a cat...
关键词：Metal-free catalyst Bis(pentafluorophenyl)(phenoxy)borane Coordination–insertion mechanism Ring-opening polymerization Polytetrahydrofuran 
Olefin Polymerization Behavior of Titanium(IV) Complexes with Fluorinated and Non-fluorinated Aliphatic Phenoxyimine Ligands
《Chinese Journal of Polymer Science》2024年第1期52-62,I0007,共12页Vladislav A.Tuskaev Kasim F.Magomedov Svetlana Ch.Gagieva Dmitry A.Kurmaev Yulia V.Nelyubina Evgenii K.Golubev Maria D.Evseeva Viktor G.Vasil'ev Galina G.Nikiforova Mikhail I.Buzin Vyacheslav S.Bogdanov Boris M.Bulychev 
supported by the Russian Science Foundation (No.22-23-00578);the financial support from the Ministry of Science and Higher Education of the Russian Federation using the equipment of Center for molecular composition studies of INEOS RAS (No.075-00697-22-00);the financial support of the Ministry of Science and Higher Education of the Russian Federation employing the equipment of Center for molecular composition studies of INEOS RAS。
A series of Ti(Ⅳ) dichloride and dialkoxide com plexes with phenoxyimine ligands containing fluorinated and nonfluorinated aliphatic imine fragments have been synthesized.The molecular structures of complexes 1 and 4...
关键词：FI catalysts Titanium(IV) (Co)polymerization Al/Mg co-catalyst Ultra-high molecular weight polyethylene 
Adsorption Characteristics of 2,4-Dichlorophenoxybutric Acid Using Bamboo Activated Carbon in a Fixed Bed
《Journal of Agricultural Chemistry and Environment》2022年第3期184-195,共12页Tae Young Kim Sung Yong Cho 
Adsorption and desorption characteristics of 2,4-dichlorophenoxybutyric acid (2,4-DB) from aqueous solution on bamboo activated carbon (BAC) were studied in a fixed bed adsorber. The adsorption equilibrium capacity of...
关键词：Adsorption DESORPTION 2 4-Dichlorophenoxybutric Acid Fixed Bed KINETIC 
Linear/branched Block Polyethylene Produced by a-Diimine Nickel(Ⅱ)Catalyst and Bis(phenoxy-imine)Zirconium Binary Catalyst System in the Presence of Diethyl Zinc被引量：1
《Chinese Journal of Polymer Science》2021年第12期1581-1589,共9页Ding-Ding Zhao Yan-Hui Hou Ke-Ning Zong Mi-Mi Cui Bin-Yuan Liu Min Yang 
by the National Natural Science Foundation of China(Nos.21004017 and 21004043);the Natural Science Foundation of Hebei Provinee(No.B2015202049).
In order to promote development of linear/branched block polyethylenes based on new catalytic systems,we synthesized a novel a.dimine nickel(Ⅱ)complex with isopropyl substituents on ortho-N-aryl and hydroxymethyl phe...
关键词：Chain shuttling polymerization Linear/branched block polyethylene a-Diimine nickel Bis(phenoxy-imine)zirconium Ethylene 
An efficient route towards R-2-phenoxypropionic acid synthesis for biotransformative production of R-2-(4-hydroxyphenoxy)propionic acid被引量：3
《Chinese Journal of Chemical Engineering》2021年第4期315-323,共9页Haiyan Zhou Yizuo Li Rui Jiang Xianlin Wang Yuanshan Wang Yaping Xue Yuguo Zheng 
Haiyan Zhou,E-mail addresses:hyzhou@zjut.edu.cn;E-mail addresses:yuanshan@zjut.edu.cn;E-mail addresses:xyp@zjut.edu.cn(Y.Xue),zhengyg@zjut.edu.cn(Y.Zheng)。
R2(4hydroxyphenoxy)propionic acid(RHPPA)is a key intermediate for the synthesis of classic herbicides with high selectivity against grassy weed.The main route for RHPPA biosynthesis is to hydroxylate the substrate R2p...
关键词：R-2-phenoxypropionic acid R-2-(4-hydroxyphenoxy)propionic acid BIOSYNTHESIS S-2-chloropropionic acid 
Phage displayed domain antibody mimics for pyrethroid and its application in immunoassay被引量：1
《International Journal of Agricultural and Biological Engineering》2020年第2期235-240,共6页Yanyan Zhao Ying Liang Yuan Liu Sicong Tu Shengming Zhao Xianjin Liu Kang Tu 
This work was supported by Key Science and Technology Project in Henan Province(202102110061,202102110060,182102110423);High Level Talent Research Project of Henan Institute of Science and Technology(2016018,2016019).
Anti-idiotypic antibodies which can mimic antigens have many potential applications in the immunoassay.This research used the monoclonal antibody of the conserved chemical region of pyrethroids,3-phenoxybenzoic acid(P...
关键词：domain antibody enzyme-linked immunosorbent assay phenoxybenzoic acid PYRETHROID 
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