Receptor Tyrosine kinases (RTKs) play a crucial role in the signal transduction pathways at cellular levels. RTK plays a vital role in cellular communication and transmission of signals to the adjacent cells and regul...
This work is supported by National Natural Science Foundation of China(82160521);Natural Science Foundation of Ningxia Province(2018A0089);Key Research and Development Program of Ningxia Province(2019BEH03003).
PI3 kinases are important for KIT signaling and KIT mutants mediated cell transformation.In order to know the difference of PI3 kinase isoforms p110αand p110δin the signaling of wild-type KIT and the often occurred ...