grant 2020YFA0509200(to LS)from the Ministry of Science and Technology of China;grant 81971487(to LS)from the National Natural Science Foundation of China;grants 20ZR1430200 and 20142202300(to LS)from the Science and Technology Commission of Shanghai Municipality;grant 20194Y0275(to JS)from the Shanghai Municipal Health Commission,and the Shanghai Frontiers Science Center of Cellular Homeostasis and Human Diseases.
Group 3 innate lymphoid cells(ILC3s)play important roles in maintaining intestinal homeostasis by protecting the host from pathogen infections and tissue inflammation.The transcription factor PLZF(promyelocytic leukem...
This work was supported by the China National Basic Research Program(2016YFA0100203);National Natural Science Foundation of China(31572399Detail,32072806,32072815,32002246);State Key Lab of Reproductive Regulation&Breeding of Grassland Livestock(SKL-OT-201801);Science and Technology Major Project of Inner Mongolia Autonomous Region of China(ZDZX2018065);and Shaanxi Province Science and Technology Innovation Team(2019TD-036);The authors thank Dr.John Clotaire Daguia Zambe for helpful comments about this paper,Jia Fang for the PGL3-NF-κB luciferase reporter plasmid,and Dong-Xue Che for bioinformatics analysis.
Double sex and mab-3-related transcription factor 1(Dmrt1),which is expressed in goat male germline stem cells(mGSCs)and Sertoli cells,is one of the most conserved transcription factors involved in sex determination.I...