Male infertility is a global issue caused by poor sperm quality,particularly motility.Enhancement of the sperm quality may improve the fertilization rate in assisted reproductive technology(ART)treatment.Scriptaid,wit...
supported by the Shanghai Municipal Health Commission Young Foundation(No.20194Y0270);Science and Technology Commission of Shanghai Municipality(No.20ZR1448100).
Phosphodiesterase(PDE)inhibitors can improve sperm motility in patients with asthenozoospermia.However,the most commonly reported nonselective PDE inhibitor pentoxifylline and PDE5 inhibitor sildenafil have the disadv...
supported by Jiangsu provincial key R&D plan special fund (Social Development)project in China (No.BE2019606).
Selective dorsal neurotomy(SDN)is a surgical treatment for primary premature ejaculation(PE),but there is still no standard surgical procedure for selecting the branches of the dorsal penile nerves to be removed.We pe...
supported by the National Natural Science Foundation of China(No.81971376 and No.81800591);the 3-year action plan to promote clinical skills and clinical innovation in municipal hospitals in Shanghai(No.16CR3067B);Shanghai Sailing Program(No.18YF1412800).
Cavernous nerve injury is an important cause of erectile dysfunction(ED).Although protective nerve technology has been widely used in nerve-sparing radical prostatectomy(nsRP),the incidence of ED is still very high af...
the National Nature Science Foundation of China(Grant No.81670625);Shandong Province Natural Science Foundation-Doctoral Fund(No.ZR2017BH104);Shandong Province Natural Science Foundation-Surface Project(No.ZR2018MH006).
This study aimed to describe endoscopic anatomy of the seminal tract and summarize our experience of transutricular seminal vesiculoscopy(TSV)guided by rea卜time transrectal ultrasonography(TRUS)in managing persistent...
Despite its widespread use for prostate cancer screening, low specificity makes PSA a suboptimal biomarker, especially in the diagnostic "gray zone" of 4-10 ng ml-1, False-positives lead to unnecessary biopsies with...
The aim of this study was to evaluate the association between semen quality and the secondary sex ratio (SSR), defined as the ratio of male to female live births. Our study cohort comprised 227 male partners who wer...
This paper was aimed to compare the clinical effectiveness and safety of adult male circumcision using the Shang RingTM (SR) with the no-flip technique compared with Dorsal Slit (DS) surgical method, A single-cent...
This study compared the efficacy of 70- and 120-w 2-μm thulium:YAG VapoEnucleation of the prostate (ThuVEP) for patients with benign prostatic obstruction (BPO). A prospective analysis of 84 patients with sympto...
This study was supported by grants from 973 programs (No. 2006CB504002 and No. 2009CB941703), National Natural Science Foundation of China (No. 30630030) and Program for Changjiang Scholars and Innovative Research Team in University (PCSIRT). We thank Professor C. Yan Cheng of the Center for Biomedical Research, Population Council, New York, USA, for his generous gift of AF-2364.
Inhibition of sperm motility has recently become a promising target for male contraceptive development. AF- 2364, an analogue of Lonidamine (LND), had a contraceptive effect when orally administered to adult Sprague...