PENTOXIFYLLINE

作品数：42被引量：194H指数：9
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相关领域：医药卫生更多>>
相关作者：裘法祖邓艳萍楼雅卿唐华吴德华更多>>
相关机构：同济医科大学北京医科大学中国人民解放军第一军医大学重庆医科大学更多>>
相关期刊：《Asian pacific Journal of Reproduction》《中国临床药理学杂志》《World Journal of Gastrointestinal Surgery》《World Journal of Hepatology》更多>>
相关基金：国家自然科学基金湖北省自然科学基金更多>>
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Clinical Efficacy of Pentoxifylline Combined with Thioctic Acid in the Treatment of Painful Diabetic Peripheral Neuropathy
《Journal of Clinical and Nursing Research》2024年第7期123-127,共5页Dengjuan Ma Shilong Zhang Peng Yao 
Objective:To observe the efficacy of pentoxifylline+thioctic acid in the treatment of patients with painful diabetic peripheral neuropathy(PDPN).Methods:70 patients with PDPN admitted from October 2019 to October 2022...
关键词：Thioctic acid PENTOXIFYLLINE Painful diabetic peripheral neuropathy EFFICACY 
Chemosensitizing effect of pentoxifylline in sensitive and multidrug-resistant non-small cell lung cancer cells
《Cancer Drug Resistance》2024年第1期712-730,共19页Beatriz S.Matos Sara Peixoto da Silva M.Helena Vasconcelos Cristina P.R.Xavier 
funded(in part)by Programa Operacional Regional do Norte and co-funded by the European Regional Development Fund under the project“The Porto Comprehensive Cancer Center”with the reference NORTE-01-0145-FEDER-072678-Consórcio PORTO.CCC-Porto.Comprehensive Cancer Center;Xavier CPR is supported by the Fundação para a Ciência e Tecnologia(FCT)and Fundo Social Europeu(FSE),Portugal,through the post-doc grant SFRH/BPD/122871/2016.
Aim:Multidrug resistance(MDR)is frequent in non-small cell lung cancer(NSCLC)patients,which can be due to its fibrotic stroma.This work explores the combination of pentoxifylline,an anti-fibrotic and chitinase 3-like-...
关键词：Chitinase 3-like-1 combined therapies drug repurposing multidrug resistance non-small cell lung cancer PENTOXIFYLLINE 
Physicochemical compatibility of pentoxifylline injection with high-concentration parenteral medications
《Pediatric Investigation》2023年第4期263-267,共5页S.M.D.K.Ganga Senarathna Tobias Strunk Michael Petrovski Sarah Woodland Kevin T.Batty 
Women&Infants Research Foundation;Department of Pharmacy at King Edward Memorial Hospital for Women。
Pentoxifylline(PTX)is reported to provide beneficial outcomes in the treatment of neonatal sepsis and serious inflammatory conditions.1,2 In the neonatal intensive care setting,PTX is administered by intravenous(IV)in...
关键词：PARENTERAL DRUGS INJECTION 
Phosphodiesterase 10A inhibitor PF-2545920 as a prospective agent for the clinical promotion of sperm motility
《Asian Journal of Andrology》2023年第5期608-615,共8页Yi-Ting Yang Bin Yan Yu-Hua Li Li-Na Guo Wei-Wei Wang Li-Jie Liu He-Guo Yu Hua Diao 
supported by the Shanghai Municipal Health Commission Young Foundation(No.20194Y0270);Science and Technology Commission of Shanghai Municipality(No.20ZR1448100).
Phosphodiesterase(PDE)inhibitors can improve sperm motility in patients with asthenozoospermia.However,the most commonly reported nonselective PDE inhibitor pentoxifylline and PDE5 inhibitor sildenafil have the disadv...
关键词：PENTOXIFYLLINE phosphodiesterase 10A SILDENAFIL sperm motility spontaneous acrosome reaction 
Antioxidant potential of pentoxifylline on spermatozoa of small ruminants
《Asian pacific Journal of Reproduction》2022年第3期138-145,共8页Mazen Alomar 
funded by Atomic Energy Commission,Syria(Project:36/ZM2-2021).
Objective:To investigate antioxidant potential of pentoxifylline on spermatozoa of small ruminants including rams and bucks.Methods:The levels of hydrogen peroxide(H2O2)production in ram and buck spermatozoa incubated...
关键词：PENTOXIFYLLINE SPERMATOZOA RAM BUCK Motiltiy Hydrogen peroxide H2O2 ANTIOXIDANTS 
Clinical outcomes and gut microbiota analysis of severe alcohol-associated hepatitis patients undergoing healthy donor fecal transplant or pentoxifylline therapy:single-center experience from Kerala被引量：2
《Gastroenterology Report》2022年第1期566-574,共9页Cyriac Abby Philips Rizwan Ahamed Sasidharan Rajesh Shobhit Singh Ajit Tharakan Jinsha K.Abduljaleel Philip Augustine 
Background Severe alcohol-associated hepatitis(SAH)patients with infections have a high short-term mortality rate.Gut microbiota dysbiosis plays an important role in the pathogenesis of SAH.Preliminary studies have de...
关键词：fecal microbiota stool transplant alcoholic hepatitis liver transplant DYSBIOSIS 
Dynamic influence of pentoxifylline on the oxygen status o Pliss＇s lymph sarcoma in rat
《Frontiers of Optoelectronics》2017年第3期317-322,共6页Tatiana I. KALGANOVA Anna G. ORLOVA German Yu. GOLUBYATNIKOV Anna V. MASLENNIKOVA Ilva V. TURCHIN 
Tumor oxygenation is one of the key factors influencing disease prognosis and the effectiveness of treatment. Assessment of tumor oxygenation levels facil- itates the selection of optimum conditions for radiation ther...
关键词：tumor oxygenation diffuse optical spectro-scopy （DOS） PENTOXIFYLLINE Pliss＇s lymph sarcoma （PLS） 
Role of nonalcoholic fatty liver disease as risk factor for drug-induced hepatotoxicity被引量：10
《Journal of Clinical & Translational Research》2017年第1期68-88,共21页Julie Massart Karima Begriche Caroline Moreau Bernard Fromenty 
Background:Obesity is often associated with nonalcoholic fatty liver disease(NAFLD),which refers to a large spectrum of hepatic lesions including fatty liver,nonalcoholic steatohepatitis(NASH)and cirrhosis.Different i...
关键词：obesity nonalcoholic fatty LIVER disease drug LIVER toxicity drug-induced LIVER injury hepatotoxicity cytochrome P450 mitochondria acetaminophen HALOTHANE ISOFLURANE methotrexate tamoxifen PENTOXIFYLLINE ROSIGLITAZONE STAVUDINE 
Pentoxifylline Inhibits Liver Fibrosis via Hedgehog Signaling Pathway
《Journal of Huazhong University of Science and Technology(Medical Sciences)》2016年第3期372-376,共5页李慧 华娟 郭春霞 王伟仙 王宝菊 杨东亮 魏屏 卢银平 
supported by grants from the National Natural Science Foundation of China(No.81371828);the Natural Science Foundation of Hubei Province(No.2011CDB396)
Infection of schistosomiasis japonica may eventually lead to liver fibrosis, and no effective antifibrotic therapies are available but liver transplantation. Hedgehog（HH） signaling pathway has been involved in the p...
关键词：pentoxifylline schistosomiasis japonica hedgehog signaling pathway macrophages hepatic stellate cells 
Spectrophotometric Study for the Reaction of Pentoxifylline Hydrochloride with 1,2-Naphthoquinone-4-Sulphonate: Kinetics, Mechanism and Application for Development of High-Throughput Kinetic Microwell Assay for Pentoxifylline in Quality Control Laboratory
《American Journal of Analytical Chemistry》2016年第2期179-191,共13页Ashraf M. Mahmoud Saad A. AlQahtani 
Spectrophotometric study was carried out, for the first time, to investigate the reaction between the vasodilator pentoxifylline hydrochloride (POX) and 1,2-naphthoquinone-4-sulphonate (NQS) reagent. The reaction occu...
关键词：Pentoxifylline HCl 1 2-Naphthoquinone-4-Sulphonate Kinetic Spectrophotometry Pharmaceutical Analysis Micro-Well Plate Reader 
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