ISOFLURANE

作品数：71被引量：202H指数：9
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相关机构：山东大学温州医科大学国立中兴大学第三军医大学新桥医院更多>>
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相关基金：国家自然科学基金国家重点基础研究发展计划北京市自然科学基金上海市青年科技启明星计划更多>>
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Multi-channel microelectrode arrays for detection of single-cell level neural information in the hippocampus CA1 under general anesthesia induced by low-dose isoflurane被引量：1
《Fundamental Research》2025年第1期72-81,共10页Ruilin Hu Penghui Fan Yiding Wang Jin Shan Luyi Jing Wei Xu Fan Mo Mixia Wang Yan Luo Ying Wang Xinxia Cai Jinping Luo 
sponsored by the National Natural Science Foundation of China(T2293731,61960206012,62121003,62171434,61971400,61975206,and 61973292);the Scientific Instrument Developing Project of the Chinese Academy of Sciences(GJJSTD20210004);the National Key Research and Development Program(2022YFC2402501,2022YFB3205602);Major Program of Scientific and Technical Innovation 2030(2021ZD0201603).
Timely monitoring of anesthesia status during surgery is important to prevent an overdose of isoflurane anesthesia.Therefore,in-depth studies of the neural mechanisms of anesthetics are warranted.Hippocampal CA1 plays...
关键词：Micro electrode array Hippocampal CA1 Isoflurane anesthesia SPIKE Local field potentials 
Development and Application of a Mitochondrial Genetically Encoded Voltage Indicator in Narcosis
《Neuroscience Bulletin》2024年第10期1529-1544,共16页Run-Zhou Yang Dian-Dian Wang Sen-Miao Li Pei-Pei Liu Jian-Sheng Kang 
supported by the National Natural Science Foundation (NSF)of China:JSK (32071137 and 92054103);Funding for Scientific Research and Innovation Team of The First Affliated Hospital of Zhengzhou University:JSK (ZYCXTD2023014)。
Mitochondrial membrane potential(MMP)plays a crucial role in the function of cells and organelles,involving various cellular physiological processes,including energy production,formation of reactive oxygen species(ROS...
关键词：M2 cortex Mitochondria Genetically encoded voltage indicators Membrane potential ROS sensitivity Fiber photometry Isoflurane-induced narcosis 
Use of a rat model to characterize 35 arterial pulse wave parameters in a comparative study of isoflurane and Zoletil/ xylazine anesthesia and the effect of Acanthopanax senticosus extract
《Animal Models and Experimental Medicine》2023年第5期474-488,共15页Anton Misak Marian Grman Lenka Tomasova Ondrej Makara Zuzana Rostakova Iveta Waczulikova Karol Ondrias 
Agency of the Slovak Republic,Grant/Award Number:2/0023/22,2/0066/23 and 2/0091/21;Slovak Research&Development Agency,Grant/Award Number:APVV-19-0154 and APVV-22-0154。
Background : Information obtained from arterial pulse waveforms (APW) can be usefulfor characterizing the cardiovascular system. To achieve this, it is necessary to know thedetailed characteristics of APWs in differen...
关键词：Acanthopanax senticosus arterial pulse waveform blood pressure hemodynamic parameters ISOFLURANE Zoletil/xylazine 
Anesthesia protocol for ear surgery in Wistar rats(animal research)
《Animal Models and Experimental Medicine》2022年第2期183-188,共6页Abhijeet Bhatia Pranjal Pratim Saikia Barilin Dkhar Haphidasara Pyngrope 
The study was a part of the research project funded by the Department of Biotechnology,Ministry of Science and Technology,Government of India(project no.BMB/2015/56)and DBT Research Associateship program(2018)。
Objective:To formulate an anesthesia protocol for safe and satisfactory anesthesia for ear surgery in rats.Methods:The rats were anesthetized with xylazine(10 mg/kg body weight)and keta-mine at doses of 80,50,40,and 3...
关键词：ISOFLURANE KETAMINE OTOLOGY Wistar rat XYLAZINE 
Lateral Hypothalamic Area Glutamatergic Neurons and Their Projections to the Lateral Habenula Modulate the Anesthetic Potency of Isoflurane in Mice被引量：10
《Neuroscience Bulletin》2021年第7期934-946,共13页Shiyi Zhao Rui Li Huiming Li Sa Wang Xinxin Zhang Dan Wang Juan Guo Huihui Li Ao Li Tingting Tong Haixing Zhong Qianzi Yang Hailong Dong 
the National Natural Science Foundation of China(81571351,81620108012,81671373,and 81771427);a Discipline Promotion Project of Xijing Hospital(XJZT18MJ33).
The lateral hypothalamic area(LHA)plays a pivotal role in regulating consciousness transition,in which orexinergic neurons,GABAergic neurons,and melanin-concentrating hormone neurons are involved.Glutamatergic neurons...
关键词：ANESTHESIA ISOFLURANE Lateral hypothalamic area Lateral habenula Glutamatergic neuron 
The neurotoxic effect of isoflurane on age-defined neurons generated from tertiary dentate matrix of dentate gyrus in mice
《解剖学杂志》2021年第S01期106-106,共1页Xiao Xinli Yang Pengbo Liu Jianxin 
Recent animal studies showed that isoflurane exposure may lead to the disturbance of hippocampal neurogenesis and later cognitive impairment.However,much less is known about the effect of isoflurane exposure on the ne...
关键词：TERTIARY MATRIX effect 
Comparison of Entropy vs. Bispectral Index Anesthetic Depth Monitoring during Isoflurane Anesthesia in Living Donor Liver Transplantation: Observational Study
《Open Journal of Anesthesiology》2021年第5期137-148,共12页Sang Hyun Lee Janie Jang Kyunga Kim Heejin Yoo Yu Jeong Bang Ji-Won Choi Gaab Soo Kim 
Liver transplantation (LT) recipients are known to require less anesthetic agents. Providing minimally required anesthetics while avoiding awareness is especially important in LT recipients because it would help manag...
关键词：Anesthetic Depth Bispectral Index ENTROPY Liver Transplantation ISOFLURANE 
Influence of Isoflurane Exposure for 15 Consecutive Days on Ovarian Function in Adult Female Mice
《Current Medical Science》2020年第6期1177-1181,共5页Xia-nan TANG Wen YAO Hai-xia YAO Yi ZHANG Jing YUE 
This work was supported by the National Key Research and Development Program(No.2018YFC1002103).
Female infertility after occupational exposure to inhaled anesthetic agents has attracted critical attention,but systematic studies focusing on the impact of inhaled anesthetics on the female reproductive system have ...
关键词：ISOFLURANE female reproductive toxicity estrous cycle ovarian hormones follicle development 
Dynamic Variations in Brain Glycogen are Involved in Modulating Isoflurane Anesthesia in Mice被引量：3
《Neuroscience Bulletin》2020年第12期1513-1523,共11页Ze Fan Zhihao Zhang Shiyi Zhao Yuanyuan Zhu Dong Guo Bo Yang Lixia Zhuo Jiao Han Rui Wang Zongping Fang Hailong Dong Yan Li Lize Xiong 
the Major Program of the National Natural Science Foundation of China(81590954);the International Cooperation and Exchange of the National Natural Science Foundation of China(81420108013);the State Key Program of National Natural Science Foundation of China(81730032)。
General anesthesia severely affects the metabolites in the brain.Glycogen,principally stored in astrocytes and providing the short-term delivery of substrates to neurons,has been implicated as an affected molecule.How...
关键词：Anesthesia-arousal Brain glycogen General anesthesia Glycogen phosphorylase Glycogen synthetase ISOFLURANE 
Brain interstitial fluid drainage and extracellular space affected by inhalational isoflurane: in comparison with intravenous sedative dexmedetomidine and pentobarbital sodium被引量：4
《Science China(Life Sciences)》2020年第9期1363-1379,共17页Guomei Zhao Hongbin Han Jun Yang Min Sun Dehua Cui Yuanyuan Li Yajuan Gao Jing Zou 
supported by the National Major Scientific Research Instrument Development Project(61827808);the National Key Basic Research Program(973 Program,2015CB856402);Beijing Brain Initiative of Beijing Municipal Science&Technology Commission(Z181100001518004);National Natural Science Foundation of China(81872051);Peking University Clinical Scientist Program(BMU2019LCKXJ007)。
Brain interstitial fluid drainage and extracellular space are closely related to waste clearance from the brain. Different anesthetics may cause different changes of brain interstitial fluid drainage and extracellular...
关键词：interstitial fluid deep brain extracellular space ISOFLURANE DEXMEDETOMIDINE pentobarbital sodium NOREPINEPHRINE 
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