STAVUDINE

作品数：14被引量：38H指数：3
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相关领域：医药卫生更多>>
相关机构：布里斯托尔-迈尔斯斯奎布公司北京理工大学更多>>
相关期刊：《Journal of Wuhan University of Technology(Materials Science)》《Pharmacology & Pharmacy》《Journal of Clinical & Translational Research》《Advances in Infectious Diseases》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划更多>>
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Role of nonalcoholic fatty liver disease as risk factor for drug-induced hepatotoxicity被引量：10
《Journal of Clinical & Translational Research》2017年第1期68-88,共21页Julie Massart Karima Begriche Caroline Moreau Bernard Fromenty 
Background:Obesity is often associated with nonalcoholic fatty liver disease(NAFLD),which refers to a large spectrum of hepatic lesions including fatty liver,nonalcoholic steatohepatitis(NASH)and cirrhosis.Different i...
关键词：obesity nonalcoholic fatty LIVER disease drug LIVER toxicity drug-induced LIVER injury hepatotoxicity cytochrome P450 mitochondria acetaminophen HALOTHANE ISOFLURANE methotrexate tamoxifen PENTOXIFYLLINE ROSIGLITAZONE STAVUDINE 
An Odyssey in antiviral drug development—50 years at the Rega Institute:1964–2014被引量：3
《Acta Pharmaceutica Sinica B》2015年第6期520-543,共24页Erik De Clercq 
I.How it started I entered the Rega Institute for Medical Research in August 1964,as a medical student,to start working under the guidance of Prof.Piet De Somer,then professor of microbiology at the Leuven School of M...
关键词：Erik De Clercq Antiviral drug Poly(I) poly(C) Polyacrylic acid Interferon Reverse transcriptase SURAMIN VALACICLOVIR Brivudin STAVUDINE Tenofovir disoproxil fumarate(TDF) Truvada~ Atripla~ Complera~/Eviplera~ Stribild~ FV-100 Mozobil~ Tenofovir alafenamide(TAF) Holy's legacy Sofosbuvir 
A Time to Event Analysis of Adverse Drug Reactions Due to Tenofovir, Zidovudine and Stavudine in a Cohort of Patients Receiving Antiretroviral Treatment at an Outpatient Clinic in Zimbabwe
《Pharmacology & Pharmacy》2015年第3期201-206,共6页Tinashe Mudzviti Nyasha T. Mudzongo Samuel Gavi Cleophas Chimbetete Charles C. Maponga Gene D. Morse 
Background: Achieving the long terms goals of antiretroviral treatment (ART) requires a careful approach during treatment initiation that takes into account patient’s psychosocial state, availability and accessibilit...
关键词：Survival ANALYSIS Electronic Medical Records ADVERSE Drug Reactions 
Immunovirologic Evaluation of Triomune (Lamivudine, Stavudine and Nevirapine) Antiretroviral Therapy in First Line HIV-1 Adult Patients in N’Djamena, Chad
《World Journal of AIDS》2014年第3期301-305,共5页Chatté Adawaye Kamangu Erick Soudy I. Djibrine Aoudalkarim Moussa Chahad Ali Mahamat Moussa Tchombou HZ Bertin Vaira Dolores Moutschen Michel 
Contexte:?The fight against HIV/AIDS epidemics is one of the greatest challenges of this century. The epidemic affects generally under-developed countries, and Sub-Saharan Africa are the most concerned. The combined m...
关键词：Plasma Viral Load Triomune ANTIRETROVIRAL Therapy Virological Failure ARVs HIV-1 First Line 
Chronic Alcohol Consumption Affects Serum Enzymes Levels in the HIV-Infected Patients on Stavudine (d4T)/Lamivudine (3TC)/Nevirapine (NVP) Treatment Regimen
《Pharmacology & Pharmacy》2014年第2期181-194,共14页Godfrey S. Bbosa David B. Kyegombe William W. Anokbonggo Aloysius Lubega Apollo Mugisha Jasper Ogwal-Okeng 
Chronic alcohol use is a common problem globally among the HIV-infected patients on ARV treatment regimens, leading to severe liver damage and increase in serum enzymes. The study determined effect of chronic alcohol ...
关键词：CHRONIC Ethanol Use Serum Enzymes HIV-INFECTED Patients ANTIRETROVIRAL (ARVs) Drugs 
An antiretroviral regimen containing 6 months of stavudine followed by long-term zidovudine for first-fine HIV therapy is optimal in resource-limited settings： a prospective, multicenter study in China被引量：7
《Chinese Medical Journal》2014年第1期59-65,共7页Li Taisheng Guo Fuping Li Yijia Zhang Chengda Han Yang Lye Wei He Yun Lu Hongzhou Xie Jing Huang Aiqiong Li Yanling Tang Xiaoping Wang Hui Zhang Tong Gao Guiju Lei Junkang Zhang Xiaoying Wu Xinhua Sun Yongtao Bai Jinsong Luo Ling Wang Huanlmg 
Background An zidovudine （AZT）-substitution regimen containing 24-week stavudine （d4T） followed by long-term AZT for HIV therapy is potential to trade off short-term AZT-related anemia and long-term risks associat...
关键词：human immunodeficiency virus acquired immunodeficiency syndrome antiretroviral therapy ZIDOVUDINE STAVUDINE anemia LIPODYSTROPHY 
Preparation, Characterization and in vitro Release of Chitosan-stavudine Conjugate Nano-prodrug被引量：1
《Journal of Wuhan University of Technology(Materials Science)》2013年第3期617-621,共5页曾戎 WANG Zehu WANG Hongran CHEN Liqiang 乔仁忠 HU Liming LI Zelin 
Funded by the National Natural Science Foundation of China(Nos.20504018,20972014,20604010,20872010 and 20732004);the National Basic Research Program of China(No.2009CB930203)
Chitosan-stavudine （d4T） conjugate with a succinic spacer was synthesized via carbodiimide coupling reaction and structurally characterized. In order to nanosize it for improving its therapeutic properties, the chit...
关键词：CHITOSAN STAVUDINE nano-prodrug polymeric conjugate 
Melanonychia in Patients Infected with Human Immunodeficiency Virus Original Communication
《Advances in Infectious Diseases》2011年第2期15-19,共5页Parvaneh Ehsanzadeh-Cheemeh Richard M. Grimes Paul Rowan Yu-Jing Huang E. James Essien Stanley T. Lewis 
This study examined whether melanonychia was more prevalent in 1) HIV positive individuals compared to HIV negative persons, 2) HIV positives exposed to zidovudine and/or stavudine and 3) those with darker skin pigmen...
关键词：ZIDOVUDINE STAVUDINE Melanonychia HIV/AIDS Skin PIGMENTATION 
世界卫生组织力促阶段性停用Stavudine药物
《基础医学与临床》2010年第10期1108-1108,共1页
据美国BIOCOMPARE科技新闻网（2009—12—25）报道，根据日内瓦路透社（Geneva，Reuters）的报道，世界卫生组织（WHO）力促阶段性地停用胸腺嘧啶核苷类似物（sta、rudine）这种最常见的AIDS药物，原因是stavudine会导致长期、不可恢复...
关键词：AIDS药物 世界卫生组织 STAVUDINE STAVUDINE 嘧啶核苷类似物 科技新闻 不良反应 怀孕妇女 
A one-year clinical trial using didanosine, stavudine and nevirapine for highly active antiretroviral therapy被引量：16
《Chinese Medical Journal》2005年第7期609-611,共3页ZHOUHua-ying ZHENGYu-huang ZHANGChun-ying DINGPei-pei ZOUWen 
Antiretroviral therapy is a key determinant in the treatment and prevention of human immunodeficiency virus (HIV) infection. Initial treatment for patients with HIV infection generally includes two nucleoside reverse ...
关键词：antiretroviral therapy highly active · didanosine · stavudine · nevirapine 
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