HALOTHANE

作品数:12被引量:24H指数:3
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相关领域:医药卫生更多>>
相关期刊:《Acta Pharmacologica Sinica》《World Journal of Gastroenterology》《Journal of Clinical & Translational Research》《Chinese Medical Sciences Journal》更多>>
相关基金:国家自然科学基金更多>>
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Role of nonalcoholic fatty liver disease as risk factor for drug-induced hepatotoxicity被引量:10
《Journal of Clinical & Translational Research》2017年第1期68-88,共21页Julie Massart Karima Begriche Caroline Moreau Bernard Fromenty 
Background:Obesity is often associated with nonalcoholic fatty liver disease(NAFLD),which refers to a large spectrum of hepatic lesions including fatty liver,nonalcoholic steatohepatitis(NASH)and cirrhosis.Different i...
关键词:obesity nonalcoholic fatty LIVER disease drug LIVER toxicity drug-induced LIVER injury hepatotoxicity cytochrome P450 mitochondria acetaminophen HALOTHANE ISOFLURANE methotrexate tamoxifen PENTOXIFYLLINE ROSIGLITAZONE STAVUDINE 
Low-dose Simvastatin Increases Skeletal Muscle Sensitivity to Caffeine and Halothane
《Chinese Medical Sciences Journal》2016年第2期107-115,共9页Xu-lei Cui Ying-lin Wang Gang Tan Ai-lun Luo Xiang-yang Guo 
Objective To determine whether the myotoxic side effects of statin simvastatin affect skeletal muscle's sensitivity to caffeine and halothane. Methods Primary cultured neonate rat skeletal myotubes were treated with 0...
关键词:SIMVASTATIN MYOPATHY CALCIUM homeostasis CAFFEINE HALOTHANE CALCIUM release 
A Mechanism for Inhaled Anesthetic-Induced Solid Organ Injury: Inflammation
《Open Journal of Anesthesiology》2014年第3期72-80,共9页Gary E. Hill Irina Gasanova Geoffrey M. Thiele 
Background: Inhaled anesthetics, including halothane, iso- and sevoflurane induce proinflammatory cytokine release. Halothane is an inhaled anesthetic agent that is metabolized by the liver into a highly reactive prod...
关键词:Anesthetic-Induced Solid Organ INFLAMMATION HALOTHANE MAA 
Role of cellular immunity in halothane hepatitis: an in vitro study
《Journal of Medical Colleges of PLA(China)》2008年第5期263-269,共7页Lu Zhijie Miao Xuerong Wang Xiaoyan Wu Jingxiang Lv Xin Yu Weifeng 
the National Natural Science Foundation of China (39900140)
Objective: To explore the effect of cellular immunity in halothane hepatitis. Methods: Hepatotoxicity model was established by exposing male Hartley guinea pigs to 1% halothane via inspiration for 4 h each time for 1 ...
关键词:Halothane hepatitis Volatile anesthetics HEPATOTOXICITY IMMUNITY CYTOTOXICITY 
Halothane hepatitis in Iran:A review of 59 cases被引量:1
《World Journal of Gastroenterology》2008年第34期5322-5326,共5页Payam Eghtesadi-Araghi Amir-Ali Sohrabpour Homayoon Vahedi Mehdi Saberi-Firoozi 
A grant from the Digestive Disease Research Center,Tehran University of Medical Sciences, Iran,No.83.36
AIM:To study halothane hepatitis (HH) in Iran and its associated risk factors. METHODS: We retrospectively studied files of all cases diagnosed with HH referred to three referral hospitals and four private centers in ...
关键词:ANESTHESIA INHALATION HALOTHANE HEPATITIS DRUG-INDUCED 
Ca^(2+) cytochemical changes of hepatotoxicity caused by halothane and sevoflurane in enzyme-induced hypoxic rats被引量:4
《World Journal of Gastroenterology》2005年第32期5025-5028,共4页Wei-Feng Yu Li-Qun Yang Mai-Tao Zhou Zhi-Qiang Liu Quan Li 
Supported by Military Medical Science Found of China, No.39400126
AIM: To investigat the relation between hepatotoxicity of halothane and sevoflurane and altered hepatic calcium homeostasis in enzyme-induced hypoxic rats. METHODS: Forty-eight rats were pretreated with phenobarbita...
关键词:Ca^2+ cytochemistry HEPATOTOXICITY Calcium homeostasis HALOTHANE SEVOFLURANE 
Effects of adenosine agonist R-phenylisopropyl-adenosine on halothane anesthesia and antinociception in rats被引量:7
《Acta Pharmacologica Sinica》2005年第2期181-185,共5页Hai-chunMA Yan-fenWANG Chun-shengFENG HuaZHAO ShujiDOHI 
Project supported by Young Teacher Research Grants from Jilin University and by Sciences and Technology Commission of Changchun(№ 0317009)
Aim:To investigate the antinociceptive effect of adenosine agonist R- phenylisopropyl-adenosine(R-PIA)given to conscious rats by intracerebro- ventricular(ICV)and intrathecal(IT),and identify the effect of R-PIA on mi...
关键词:ADENOSINE inhalation anesthesia ANALGESIA potassium channels subarachnoid space cerebral ventricles 
CO-EXPRESSION OF WIND-UP IN BOTH DORSAL HORN WDR UNIT AND FLEXOR SIGLE MOTOR UNIT INDUCED BY CUTANEOUS ELECTRICAL STIMULI IN HALOTHANE-ANESTHETIZED RATS
《神经解剖学杂志》2001年第B07期111-111,共1页Lars Arendt-Nielsen Carsten Dahl Nielsen 
Aim: The present project is to seek the possible electrical stimulation parameter by which wind-up of withdrawal reflex of rats and set up a appropriate animal model for recording the withdrawal reflex of wind-up phen...
关键词:氟烷麻醉大白鼠 皮肤电刺激 背角神经元 WDR 肌电 运动 共表达 终止反射 
Experimental research on phospholipids variation of halothane on liver mitochondria被引量:1
《World Journal of Gastroenterology》1999年第1期33-35,共3页SUI Bo 1, ZHANG Guang Ming 2, YU Wei Feng 3, WANG Xue Min 4, MA Yong De 1 and LIU Shu Xiao 5 
AIM To study the pathogenesis of hepatotoxicity of halothane. METHODS The effect of different concentration of halothane and sevoflurane on mitochondrial membrane phospholipids composition of rat liver were analyze...
关键词:HALOTHANE SEVOFLURANE LIVER MITOCHONDRIA HPLC HEPATOTOXICITY 
The position research of the effect of methoxyflurane, halothane,enflurane and isoflurane anesthesia on diencophalon of the rat
《Journal of Medical Colleges of PLA(China)》1998年第3期164-167,共4页徐礼鲜 张晓峰 马加海 卢玲玲 张国良 张洪凯 孙辉 
Objective To understand the regulation and control of the position of the diencophalon followingmethoxyflurane. halothane, enflurane and isoflurane anesthesia. Methods: By using Fos--oncoprotein antibody immunohistoch...
关键词:INHALATION ANESTHETIC diencophalon C-FOS ONCOGENE 
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