SEVOFLURANE

作品数：111被引量：486H指数：12
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相关领域：医药卫生更多>>
相关作者：于金贵张国华郑晖孙莉阎涛更多>>
相关机构：山东大学中国医学科学院肿瘤医院军事医学科学院江苏省麻醉学重点实验室更多>>
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相关基金：国家自然科学基金江苏省自然科学基金湖北省自然科学基金国家重点基础研究发展计划更多>>
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Single-Nucleus Transcriptomic Taxonomy of Multiple Sevoflurane-Induced Cell Type Specificity in the Hippocampus of Juvenile Non-human Primates
《Neuroscience Bulletin》2024年第12期1943-1949,共7页Yanyong Cheng Xiao Chen Jia Yan Lei Zhang Hong Jiang 
supported by the National Natural Science Foundation of China(82201321,82171173,and 82071177);the Science and Technology Commission of Shanghai Municipality(22YF1422500);the Shanghai Ninth People’s Hospital(JYZP001).
Dear Editor,The widespread and growing use of anesthesia in children makes its safety a major health issue of interest.Mounting evidence suggests that anesthetic exposure during early development may result in neurolo...
关键词：ANESTHESIA IMPAIRMENT Mount 
Triggering Receptor Expressed on Myeloid Cells 2 Alleviated Sevoflurane-Induced Developmental Neurotoxicity via Microglial Pruning of Dendritic Spines in the CA1 Region of the Hippocampus
《Neuroscience Bulletin》2024年第9期1215-1229,共15页Li Deng Shao-Yong Song Wei-Ming Zhao Xiao-Wen Meng Hong Liu Qing Zheng Ke Peng Fu-Hai Ji 
National Natural Science Foundation of China(82072130 and 82001126);Key Medical Research Projects in Jiangsu Province(ZD2022021);Six Talent Peaks Project in Jiangsu Province(WSN-022);Suzhou Clinical Medical Center for Anaesthesiology(Szlcyxzxj202102);Jiangsu Medical Association Anaesthesia Research Project(SYH-32021-0036(2021031));Suzhou Medical Health Science and Technology Innovation Project(SKY2022136);Jiangsu Provincial Colleges of Natural Science General Program(22KJD320002);Health Talent Plan Project in Suzhou(GSWS2022007);Gusu Health Talent Project of Soochow(GSWS2021062).
Sevoflurane induces developmental neurotoxicity in mice;however,the underlying mechanisms remain unclear.Triggering receptor expressed on myeloid cells 2(TREM2)is essential for microglia-mediated synaptic refinement d...
关键词：CA1 neurons Dendritic spines Developmental neurotoxicity MICROGLIA SEVOFLURANE TREM2 
Respiratory complications of propofol,sevoflurane,and dexmedetomidine anesthesia for fiberoptic bronchoscopy in children aged 1 month to 3 years:a randomized trial
《南方医科大学学报》2024年第9期1631-1636,共6页Amir Shafa Mohammad Montasery Sedighe Shahhosseini Majid Keivanfar Asieh Maghami Mehr Mahtab Ebrahim Babaei Mohammad Jafari 
Objective To evaluate the effect of propofol,sevoflurane,and dexmedetomidine on respiratory complications inchildren undergoing fiberoptic bronchoscopy(FOB).Methods This double-blind randomized clinical trial was cond...
关键词：fiberoptic bronchoscopy PROPOFOL SEVOFLURANE DEXMEDETOMIDINE CHILDREN 
Integrated ribosome and proteome analyses reveal insights into sevoflurane-induced long-term social behavior and cognitive dysfunctions through ADNP inhibition in neonatal mice被引量：1
《Zoological Research》2024年第3期663-678,共16页Li-Rong Liang Bing Liu Shu-Hui Cao You-Yi Zhao Tian Zeng Mei-Ting Zhai Ze Fan Dan-Yi He San-Xin Ma Xiao-Tong Shi Yao Zhang Hui Zhang 
supported by the National Natural Science Foundation of China(82171170,81971076,82371277 to H.Z.,82101345 to L.R.L.)。
A growing number of studies have demonstrated that repeated exposure to sevoflurane during development results in persistent social abnormalities and cognitive impairment.Davunetide,an active fragment of the activity-...
关键词：Davunetide SEVOFLURANE Abnormal social behaviors ADNP NEUROTOXICITY 
Is it a normal phenomenon for pediatric patients to have brain leptomeningeal contrast enhancement on 3-tesla magnetic resonance imaging?
《World Journal of Radiology》2024年第5期136-138,共3页Min Ai Hang-Hang Zhang Yi Guo Jun-Bang Feng 
Supported by the Chongging Medical Scientific Research Project(Joint Project of Chongqing Health Commission and Science and Technology Bureau),No.2022QNXM013 and No.2023MSXM016.
Determining whether sevoflurane sedation in children leads to“pseudo”prominent leptomeningeal contrast enhancement(pLMCE)on 3 Tesla magnetic resonance imaging will help reduce overdiagnosis by radiologists and clari...
关键词：Pediatrics patients SEVOFLURANE BRAIN Prominent leptomeningeal contrast enhancement Magnetic resonance imaging 
Effects of sevoflurane on left ventricular function by speckletracking echocardiography in coronary bypass patients: A randomized trial
《The Journal of Biomedical Research》2024年第1期76-86,共11页Chanjuan Gong Xiaokai Zhou Yin Fang Yanjuan Zhang Linjia Zhu Zhengnian Ding 
supported by Jiangsu Province Hospital(the First Affiliated Hospital of Nanjing Medical University)Clinical Capacity Enhancement and was awarded to the first author,Chanjuan Gong(Grant No.JSPH-MC-2022-4).
The present study aimed to dynamically observe the segmental and global myocardial movements of the left ventricle during coronary artery bypass grafting by transesophageal speckle-tracking echocardiography,and to ass...
关键词：coronary artery bypass grafting speckle-tracking echocardiography SEVOFLURANE transesophageal echocardiography 
Neuron-derived exosomes mediate sevoflurane-induced neurotoxicity in neonatal mice via transferring lncRNA Gas5 and promoting M1 polarization of microglia被引量：1
《Acta Pharmacologica Sinica》2024年第2期298-311,共14页Li-li Xu Jia-qian Xie Jian-jun Shen Mei-dan Ying Xin-zhong Chen 
supported by the National Natural Science Foundation of China(82271287);the Exploration Project of Zhejiang Natural Science Foundation(LY21H090006);the Zhejiang Health Science and Technology Planning Project(2021KY768);the Bureau of Chinese Medicine,Zhejiang,China(2018ZB065);supported by grants from the Nanhu Brain-computer Interface Institute(010902001).
Sevoflurane exposure during rapid brain development induces neuronal apoptosis and causes memory and cognitive deficits in neonatal mice.Exosomes that transfer genetic materials including long non-coding RNAs(lncRNAs)...
关键词：SEVOFLURANE EXOSOME lncRNA Gas5 MICROGLIA NEUROTOXICITY 
Impact of propofol and sevoflurane anesthesia on cognition and emotion in gastric cancer patients undergoing radical resection被引量：3
《World Journal of Gastrointestinal Oncology》2024年第1期79-89,共11页Ao-Han Li Su Bu Ling Wang Ai-Min Liang Hui-Yu Luo 
BACKGROUND Propofol and sevoflurane are commonly used anesthetic agents for maintenance anesthesia during radical resection of gastric cancer.However,there is a debate concerning their differential effects on cognitiv...
关键词：PROPOFOL SEVOFLURANE Radical resection of gastric cancer Anesthetic effect Cognitive function Negative emotion 
Protective effect of sevoflurane on lung function of elderly chronic obstructive pulmonary disease patients undergoing total hip arthroplasty
《World Journal of Clinical Cases》2023年第31期7619-7628,共10页Yuan Yao Man-Si Zhang Yue-Bing Li Ming-Zhe Zhang 
This study was registered in February 2018.Registration identification number is ChiCTR1900021234.
BACKGROUND Chronic obstructive pulmonary disease(COPD)is a common respiratory disorder that affects the elderly population and increases the risk of postoperative pulmonary complications(PPCs)after major surgeries.Sev...
关键词：SEVOFLURANE PROPOFOL Lung function Chronic obstructive pulmonary disease Total hip arthroplasty Elderly patients Inflammatory markers 
Effects of Sevoflurane and Propofol on Neurological Recovery of Traumatic Brain Injury Patients in the Early Postoperative Stage: A Retrospective Cohort Study
《Chinese Medical Sciences Journal》2023年第2期97-108,共12页Bei Wu Wan-Qing Song Jin-Qian Dong Hong-Li Yue Yu Lu Yun Yu Shu-Yu Hao Bai-Yun Liu Wei-Hua Cui 
Beijing Natural Sciences Foundation(7173255);Beijing Municipal Administration of Hospital Incubating Program(PX2019019).
Objective To investigate the effects of propofol and sevoflurane on neurological recovery of traumatic brain injury(TBI)patients in the early postoperative stage.Methods We retrospectively analyzed the clinical data o...
关键词：Glasgow Coma Scale Glasgow Outcome Scale PROPOFOL SEVOFLURANE traumatic brain injury 
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