In this editorial,we comment on the article by Zhao et al which highlighted how patients having nonalcoholic fatty liver disease(NAFLD)were more susceptible to drug-induced lung injury(DILI).This article looked at the...
Rationale:Opioids,the class of drugs,frequently used for pain relief in acute pancreatitis are known to act as a dual-edged sword.They are capable of causing acute pancreatitis though very rare.Patient’s Concern:A 45...
Alectinib is a selective Anaplastic Lymphoma Kinase (ALK) tyrosine kinase inhibitor used as standard therapy for ALK-rearranged lung adenocarcinoma. Hemolytic anemia is considered a rare but significant adverse event ...
In a recent publication in Cell,a multidisciplinary academic drug discovery team,with its spin-off HepaRegeniX,published a first-in-class small molecule MKK4 inhibitor(HRX215)with remarkable efficacy in multiple precl...
Introduction:Toxic epidermal necrolysis(TEN)is a medical emergency that most commonly occurs as an adverse effect of certain drugs.Here,we describe a case of a 41-year-old man with no comorbid illness who developed TE...
Several features of drug-induced mucosal alterations have been observed in the upper gastrointestinal tract,i.e.,the esophagus,stomach,and duodenum.These include pill-induced esophagitis,desquamative esophagitis,worse...
supported by the CAMS Innovation Fund for Medical Sciences(CIFMS)(2021-1-I2M-006,2023-I2M-1-003,2022-I2M-2-001,2021-1-I2M-019);the National Natural Science Foundation of China(82070287,82088101 and 82025004);the National Key Research and Development Program of China(2022YFA1104500)。
Mitochondrial toxicity induced by therapeutic drugs is a major contributor for cardiotoxicity,posing a serious threat to pharmaceutical industries and patients’lives.However,mitochondrial toxicity testing is not inco...
Scientific Research Project of Heilongjiang Provincial Education Department(No.12531608)。
Objective:To study the effect of Yigan capsule on the expression of high mobility group protein B1(HMGB1),nuclear factor-B(NF-κB)and receptor for advanced glycation end products(RAGE)in anti-tuberculosis drug-induced...
BACKGROUND This case report addresses the dearth of effective therapeutic interventions for central nervous system metastases in patients with HER2-negative breast cancer.It presents a unique case of a woman with estr...
Dr.Vishwanath Karad MIT-World Peace University,Pune,411038 India and Dr.D.Y.Patil Dental College,and Hospital,Pimpri,Pune-411018 India.
Orthodontic procedures can be inconvenient in nature.To overcome this problem,accelerated orthodontics play a very important role to reduce existing trouble and discomfort.The most common inconvenience caused during o...