PROSTATE_CANCER

作品数：1256被引量：2510H指数：19
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相关作者：王增军邱实黄鹰段秀枝魏强更多>>
相关机构：浙江大学医学院附属第二医院江苏省人民医院复旦大学上海交通大学医学院附属第九人民医院更多>>
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ADP‑dependent glucokinase:the ancient,archaeal key to prostate cancer
《Military Medical Research》2025年第3期467-468,共2页Marcin M.Kamiński 
The December 2023 issue of the Military Medical Research brings out an astounding discover y by Xu et al.[1]demonstrating a key role of the mysterious enzyme ADPdependent glucokinase(ADPGK)in the cellular metabolism o...
关键词：ADP-dependent glucokinase(ADPGK) Prostate cancer Prognostic marker ADENOCARCINOMA AMPactivated protein kinase(AMPK) Aldolase C(ALDOC) 
Allele-specific methylation of the PSA promoter in prostate cells:A new translational marker for the differential diagnosis of prostate cancer
《Genes & Diseases》2025年第3期61-63,共3页Mikhail Baryshev Irina Maksimova Ilona Sasoveca 
supported by the internal grant of the Rıga Stradin‚s University(No.132311).
DNA methylation is one of the mechanisms of epigenetic control of gene expression,and a change in the intrinsic pattern can lead to various diseases and disorders.At the same time,this makes DNA methylation a disease-...
关键词：dna methylation prostate adenocarcinoma prostate cancer pca tumor marker allele specific methylation epigenetic control gene expressionand prostate cells psa promoter 
The implications of single-cell RNA-seq analysis in prostate cancer:unraveling tumor heterogeneity,therapeutic implications and pathways towards personalized therapy
《Military Medical Research》2025年第2期220-241,共22页De-Chao Feng Wei-Zhen Zhu Jie Wang Deng-Xiong Li Xu Shi Qiao Xiong Jia You Ping Han Shi Qiu Qiang Wei Lu Yang 
Chinese Scholarship Council(202206240086);National Natural Science Foundation of China(81974099,82170785,81974098,82170784);National Key Research and Development Program of China(2021YFC2009303);programs from Science and Technology Department of Sichuan Province(2021YFH0172);Young Investigator Award of Sichuan University 2017(2017SCU04A17);Technology Innovation Research and Development Project of Chengdu Science and Technology Bureau(2019-YF05-00296-SN);Sichuan University-Panzhihua science and technology cooperation special fund(2020CDPZH-4).
In recent years,advancements in single-cell and spatial transcriptomics,which are highly regarded developments in the current era,particularly the emerging integration of single-cell and spatiotemporal transcriptomics...
关键词：Prostate cancer Single-cell RNA sequencing(scRNA-seq) Tumor microenvironment Tumor heterogeneity Treatment resistance Precision medicine 
Association between maximal urethral length preservation and postoperative continence after robot-assisted radical prostatectomy:a meta-analysis and systematic review
《Asian Journal of Andrology》2025年第2期225-230,共6页Tian-Yu Xiong Zhan-Liang Liu Hao-Yu Wu Yun-Peng Fan Yi-Nong Niu 
supported by the National Natural Science Foundation of China(No.82170783).
Urinary incontinence is a common complication following robot-assisted radical prostatectomy(RARP).Urethral length has been identified as a factor affecting postoperative continence recovery.In this meta-analysis,we e...
关键词：prostate cancer prostatectomy robot-assisted surgery urinary incontinence 
ERLNs augment simultaneous delivery of GFSV into PC-3 cells:Influence of drug combination on SDH,GPX-4,5α-RD,and cytotoxicity
《Oncology Research》2025年第4期919-935,共17页RIYAD F.ALZHRANI LAMA BINOBAID ABDULAZIZ A.ALORAINI MESHAL S.ALSAHLI AHMED H.BAKHEIT HANADI H.ASIRI SABRY M.ATTIA ALI ALHOSHANI GAMALELDIN I.HARISA 
Objective:Prostate cancer(PCA)is the second most widespread cancer among men globally,with a rising mortality rate.Enzyme-responsive lipid nanoparticles(ERLNs)are promising vectors for the selective delivery of antica...
关键词：Prostate cancer(PCA) Nanoparticle biocompatibility Molecular docking simulation(MDS) Apoptosis Drug repurposing 
Androgen receptor inhibitors in treating prostate cancer
《Asian Journal of Andrology》2025年第2期144-155,共12页Ryan N Cole Qinghua Fang Kanako Matsuoka Zhou Wang 
supported in part by DOD Idea Development Award(HT9425-23-1-0295);NIH grants(R01 CA265897 and R21 CA280467);by the Department of Urology,University of Pittsburgh School of Medicine,Pittsburgh,PA,USA。
Androgens play an important role in prostate cancer development and progression.Androgen action is mediated through the androgen receptor(AR),a ligand-dependent DNA-binding transcription factor.AR is arguably the most...
关键词：androgen receptor ANTI-ANDROGENS prostate cancer 
Integrative analysis of cuproptosis-related IncRNAs:Unveiling prognostic significance,immune microenvironment,and copper-induced mechanisms in prostate cancer
《Cancer Pathogenesis and Therapy》2025年第1期48-59,共12页Haitao Zhong Yiming Lai Wenhao Ouyang Yunfang Yu Yongxin Wu Xinxin He Lexiang Zeng Xueen Qiu Peixian Chen Lingfeng Li Jie Zhou Tianlong Luo Hai Huang 
supported by grants from the National Natural Science Foundation of China(Nos.82372912,81802527,81972471,82073408,81974395,and 82173036);National Key Research and Development Program of China(Nos.2022YFC3602900 and 2022YFC3602904);BeijingBethune CharitableFoundation(Nos.mnzl202001 and mnzl202026);Guangzhou Science and Technology Project(Nos.202206010078 and 202201020574);Sun Yat-sen University Clinical Research 5010 Program(Nos.2018007 and 2019005);Sun Yat-sen Clinical Research Cultivating Program(No.SYS-C-201801);Guangdong Medical Science and Technology Program(No.A2020558);Tencent Charity Foundation(No.7670020025);Scientific Research Launch Project of Sun Yat-sen Memorial Hospital(No.YXQH202209);GuangdongBasicand AppliedBasicResearchFoundation(No.2019A1515011437);International Science and Technology Cooperation Project Plan of Guangdong Province(No.2021A0505030085);Guangzhou Science and Technology Key R&D Project(No.202206010117);Beijing CSCO Clinical Oncology Research Foundation(No.Y-tongshu2021/ms-0162);Guangdong Provincial Clinical Research Center for Urological Diseases(No.2020B1111170006);Guangdong Science and Technology Department(No.2020B1212060018);open research funds from the Sixth Affiliated Hospital of Guangzhou Medical University,Qingyuan People's Hospital.
Background:Long non-coding ribonucleic acids(lncRNAs)regulate messenger RNA(mRNA)expression and influence cancer development and progression.Cuproptosis,a newly discovered form of cell death,plays an important role in...
关键词：Prostate cancer Cuproptosis Deep learning IncRNAs 
Advancements in molecular imaging probes for precision diagnosis and treatment of prostate cancer
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2025年第2期124-144,共21页Jiajie FANG Ahmad ALHASKAWI Yanzhao DONG Cheng CHENG Zhijie XU Junjie TIAN Sahar Ahmed ABDALBARY Hui LU 
supported by the Medical Health Science and Technology Project of Zhejiang Provincial Health Com-mission(No.2022RC146);the Zhejiang Provincial Natural Science Foundation of China(No.LQ22H050003).
Prostate cancer is the second most common cancer in men,accounting for 14.1%of new cancer cases in 2020.The aggressiveness of prostate cancer is highly variable,depending on its grade and stage at the time of diagnosi...
关键词：Molecular imaging Prostate cancer Nuclear medicine Prostate-specific membrane antigen(PSMA) NANOPARTICLE 
Integrated analysis of single-cell and bulk transcriptomes uncovers clinically relevant molecular subtypes in human prostate cancer
《Chinese Journal of Cancer Research》2025年第1期90-114,共25页Tao Ding Lina He Guowen Lin Lei Xu Yanjun Zhu Xinan Wang Xuefei Liu Jianming Guo Fanghong Lei Zhixiang Zuo Jianghua Zheng 
supported by Shanghai Science and Technology Commission,China(No.21S11902100);Shanghai Municipal Health Commission Scientific Research Project(No.202140308);Clinical Research Project of Tongji Hospital of Tongji University[No.ITJ(ZD)2209];Shanghai Tongji Hospital National Natural Science Foundation Cultivation Project(No.GJPY2216);Shanghai Medical Innovation Research Special Foundation(No.23Y11908800);CSCO-Haosen Oncology Research Fund(No.Y-HS202301-0096).
Objective:Prostate cancer(PCa)is a complex disease characterized by diverse cellular ecosystems within the tumor microenvironment(TME)and high tumor heterogeneity,which challenges clinically stratified management and ...
关键词：Single-cell RNA sequencing prostate cancer lineage plasticity tumor heterogeneity molecular classification 
Overview of the Impact of PSMA PET on the Management of Prostate Cancer Patients
《Journal of Biosciences and Medicines》2025年第2期169-189,共21页Jinyu Zhang Xin Dai Xinyi Ren Yuxin Zheng Jia Liu Gang Cheng 
Prostate cancer (PCa) is the second most common type of cancer among men worldwide and one of the leading causes of cancer-related deaths. According to data from the World Health Organization (WHO), this cancer causes...
关键词：PSMA PET Prostate Cancer Molecular Imaging Radioligand Therapy 
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