云南高校图书馆联盟文献共享服务平台- PROTEIN

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Efficient Chemical Synthesis and Folding of Mirror-Image Tropomyosin Receptor Kinase A Using the Strategy of Removable Glycosylation Modification: 《Chinese Journal of Chemistry》2024年第19期2316-2322,共7页Tongyue Wang Weiwei Shi Guo-Chao Chu Yi-Ming Li; supported by the National Natural Science Foundation of China(Nos.22227810,22277020,22307061);China Postdoctoral Science Foundation(No.2022M721801);the Beijing Life Science Academy(No.2023000cc0130).; Comprehensive Summary The strategy of removable glycosylation modification was used to overcome the low-efficiency problem encountered in the chemical synthesis of the mirror-image D-version of the immunoglobulin(Ig)-...; 关键词：Chemical protein synthesis Removable glycosylation modification Synthetic methods Protein folding D-protein

Quantum model for understanding protein misfolding behavior——phase diagram and manual intervention: 《Science China(Physics,Mechanics & Astronomy)》2021年第6期10-16,共7页Wen-Wen Mao Li-Hua Lu You-Quan Li; supported by the National Key Research and Development Program of China(Grant No.2017YFA0304304);the National Natural Science Foundation of China(Grant No.11935012)。; The study of protein folding is fundamental and important in the multidisciplinary field because a diversity of diseases,like Alzheimer’s and Parkinson’s are relevant to protein misfolding.The current thermodynamic ...; 关键词：quantum phase diagram quantum walk mean first-passage time protein folding

Quantum intelligence on protein folding pathways: 《Chinese Physics B》2020年第1期107-112,共6页Wen-Wen Mao Li-Hua Lv Yong-Yun Ji You-Quan Li; Project supported by the National Key Research and Development Program of China(Grant No.2017YFA0304304);the National Natural Science Foundation of China(Grant No.11935012); We study the protein folding problem on the base of our quantum approach by considering the model of protein chain with nine amino-acid residues.We introduce the concept of distance space and its projections on a XY-p...; 关键词：protein folding quantum walk shortest pathways mean first passage time

Single Molecule Thermodynamics Hypothesis of Protein Folding and Drug Design: 《Journal of Biosciences and Medicines》2019年第11期164-172,共9页Fang Yi; 关键词：Protein FOLDING CONFORMATION THERMODYNAMIC System Gibbs Free Energy Single Molecule MACROSCOPIC Quantum Statistics

The Important Roles of Water in Protein Folding:an Approach by Single Molecule Force Spectroscopy被引量：2: 《Chinese Journal of Polymer Science》2018年第3期379-384,共6页Bo Cheng Shu-Xun Cui; financially supported by the National Natural Science Foundation of China(Nos.21574106 and 21604074);the Sichuan Province Youth Science and Technology Innovation Team(Nos.2016TD0026 and 2017JQ0009); The single-chain elasticity of a completely unfolded protein （027）8, modules of human cardiac titin） is studied in different liquid environments by the atomic force microscopy （AFM）-based single molecule force sp...; 关键词：SMFS PROTEIN FOLDING WATER

Quantum conformational transition in biological macromolecule: 《Frontiers of Electrical and Electronic Engineering in China》2017年第2期143-158,共16页Liaofu Luo Jun Lv; Background： Recently we proposed a quantum theory on the conformational change of biomolecule, deduced several equations on protein folding rate from the first principles and discussed the experimental tests of the t...; 关键词：conformational change quantum transition protein folding RNA folding temperature dependence

Role of Interfacial Viscosity and pH in L-Phenylalanine,L-Tryptophan Molecular Rotors: 《光谱学与光谱分析》2016年第5期1629-1633,共5页N.Meenakshisundaram Kamatchi Sankaranarayanan; Protein folding involves the aminoacid sequence to come forth and form an energy minimized structure.Recently molecular crowding leading to increase in viscosity is said to be one of the major concerns affecting prote...; 关键词：Protein folding Molecular crowders Interfacial viscosity Fluorescent probes

Thermodynamic Principle Revisited: Theory of Protein Folding: 《Advances in Bioscience and Biotechnology》2015年第1期37-48,共12页Yi Fang; Anfinsen’s thermodynamic hypothesis is reviewed and misunderstandings are clarified. It really should be called the thermodynamic principle of protein folding. Energy landscape is really just the mathematical graph o...; 关键词：PROTEIN FOLDING Gibbs Free Energy QUANTUM Statistic Single MOLECULE

Tightening up the structure, lighting up the pathway:application of molecular constraints and light to manipulate protein folding, self-assembly and function: 《Science China Chemistry》2014年第12期1615-1624,共10页MARKIEWICZ Beatrice N. CULIK Robert M. GAI Feng; supported by the National Institutes of Health(GM-065978,AG-039253); Chemical cross-linking provides an effective avenue to reduce the conformational entropy of polypeptide chains and hence has become a popular method to induce or force structural formation in peptides and proteins.Rec...; 关键词：protein folding aggregation SELF-ASSEMBLY CROSS-LINKER phototrigger light-activation

A Gibbs free energy formula for protein folding derived from quantum statistics被引量：1: 《Science China(Physics,Mechanics & Astronomy)》2014年第8期1547-1551,共5页FANG Yi; The fundamental law for protein folding is the thermodynamic principle.The amino acid sequence of a protein determines its native structure and the native structure has the minimum Gibbs free energy.Lacking of a Gibbs...; 关键词：protein folding Gibbs free energy quantum mechanics statistical mechanics globular protein

PROTEIN_FOLDING