financially supported by the National Natural Science Foundation of China (Nos. 22077088, 21877082,U21A20308);the Foundation from the Science and Technology Department of Sichuan Province (Nos. 2020JDJQ0017,2021YFH0132, 2020ZHCG0097)。
Recently, hydrogen-bonding has attracted extensive attention in the design of chromophores. Here, a new class of hydrogen-bond locked purine chromophores(HOPs) were reported by introducing a hydroxyphenyl group into t...
supported by the National Natural Science Foundation of China(Nos. 21562013 and 21362004);Subsidy Project for Outstanding Key Laboratory of Guizhou Province in China(No. 20154004);the Provincial University Cooperation Plan of Guizhou Province in China(No. 20147001);Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan
A series of novel chalcone derivatives containing purine moiety was designed and synthesized, and their antiviral activities against cucumber mosaic virus (CMV) and tobacco mosaic virus (TMV) were evaluated in viv...
the National Natural Science Foundation of China (No. 21202039);the Program for Science & Technology Innovation Talents in Universities of Henan Province (No. 13HASTIT013);the Foundation for University Young Key Teacher by Henan Province of China (No. 2011GGJS132)
C8-Alkyl-substituted purine analogues were synthesized through direct alkylation of 8-H purine with tetrahydrofuran in the presence of Co catalyst in one step. The reactions gave a series of novel C8-oxygen heterocycl...
the Natural Science Foundation of Zhejiang Province(No.LY13B020015);Zhejiang Key Innovation Team of Green Pharmaceutical Technology(No.2012R10043-07) for financial support
An efficient and regioselective synthesis of N-9 alkoxyalkylated purine nucleoside derivatives was achieved via the N-alkoxyalkylation of purine rings with vinyl ethers catalyzed by L-ProT.The advantages of this proto...
Two bridged purine dinucleosides, bis(2-N-acetyl-6-N-alkylylene-2,6-diaminopurine-2',3',5'-triacetyl-beta-D-ribofuranoside), were synthesized fi om the reaction of the key medium 3, 2-acetylamino-6-[1-(1,2,4-triazolyl...
The retention behaviours of 12 purine and pyrimidine derivatives thymine,uracil,cytosine,adenine,guanine,xanthine,hypoxanthine, purine, 4,6 diaminopyrimidine,tpeophylline,trimethoprimum and 6 (benzylamino)purine...
The newly isolated purine alkaloid,an open chain nucleoside-ganoderpurine natural product, was synthesized by the Michael addition of adenine to mesityl oxide.