PURINE

作品数:73被引量:102H指数:5
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相关领域:医药卫生理学更多>>
相关作者:张礼和杨振军郑焕鑫孙超更多>>
相关机构:北京大学信息技术有限公司中国医学科学院北京协和医学院中国科学技术大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划广西壮族自治区自然科学基金更多>>
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Hydrogen-bond locked purine chromophores with high photostability for lipid droplets imaging in cells and tissues
《Chinese Chemical Letters》2023年第4期300-303,共4页Jinlin Zhou Kun Li Lei Shi Hong Zhang Haoyuan Wang Yimin Shan Shanyong Chen Xiao-Qi Yu 
financially supported by the National Natural Science Foundation of China (Nos. 22077088, 21877082,U21A20308);the Foundation from the Science and Technology Department of Sichuan Province (Nos. 2020JDJQ0017,2021YFH0132, 2020ZHCG0097)。
Recently, hydrogen-bonding has attracted extensive attention in the design of chromophores. Here, a new class of hydrogen-bond locked purine chromophores(HOPs) were reported by introducing a hydroxyphenyl group into t...
关键词:Fluorescent probe PURINE Hydrogen bond Lipid droplets Fatty liver 
Synthesis and antiviral bioactivity of novel chalcone derivatives containing purine moiety
《Chinese Chemical Letters》2018年第1期127-130,共4页Yan-Jiao Wang Da-Gui Zhou Fang-Cheng He Ji-Xiang Chen Yong-Zhong Chen Xiu-Hai Gan De-Yu Hu Bao-An Song 
supported by the National Natural Science Foundation of China(Nos. 21562013 and 21362004);Subsidy Project for Outstanding Key Laboratory of Guizhou Province in China(No. 20154004);the Provincial University Cooperation Plan of Guizhou Province in China(No. 20147001);Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan
A series of novel chalcone derivatives containing purine moiety was designed and synthesized, and their antiviral activities against cucumber mosaic virus (CMV) and tobacco mosaic virus (TMV) were evaluated in viv...
关键词:Chalcone derivatives6-Chloro-purineAntiviral activityCucumber mosaic virusTobacco mosaic virusInteraction mechanisms 
Synthesis of C8-alkyl-substituted purine analogues by direct alkylation of 8-H purines with tetrahydrofuran catalyzed by CoCl2·6H2O被引量:1
《Chinese Chemical Letters》2017年第1期105-108,共4页Hong-Ying Niu Ling-Yun Su Shi-Xia Bai Jian-Ping Li Xi-Lan Feng Hai-Ming Guo 
the National Natural Science Foundation of China (No. 21202039);the Program for Science & Technology Innovation Talents in Universities of Henan Province (No. 13HASTIT013);the Foundation for University Young Key Teacher by Henan Province of China (No. 2011GGJS132)
C8-Alkyl-substituted purine analogues were synthesized through direct alkylation of 8-H purine with tetrahydrofuran in the presence of Co catalyst in one step. The reactions gave a series of novel C8-oxygen heterocycl...
关键词:PURINE C-H activation ALKYLATION TETRAHYDROFURAN Co-catalyzed 
L-ProT catalyzed highly regioselective N-alkoxyalkylation of purine rings with vinyl ethers被引量:1
《Chinese Chemical Letters》2014年第10期1341-1345,共5页Jian-Jun Li Xing-Xing Gui 
the Natural Science Foundation of Zhejiang Province(No.LY13B020015);Zhejiang Key Innovation Team of Green Pharmaceutical Technology(No.2012R10043-07) for financial support
An efficient and regioselective synthesis of N-9 alkoxyalkylated purine nucleoside derivatives was achieved via the N-alkoxyalkylation of purine rings with vinyl ethers catalyzed by L-ProT.The advantages of this proto...
关键词:L-Proline triflate Regioselectivity Purine Vinyl ether Addition reaction 
The Synthesis of Bridged Purine Dinucleoside
《Chinese Chemical Letters》1997年第8期691-692,共2页Xiao Hua XU ZhiYuan SUN Zhong Biao ZHANG Guo Chen CHI RuYu CHEN(Institute of Elemento-Organic Chemsitry,The State Key Laboratory of Elemento-organic Chemistry)(Nankai University, Tianjin 300071) 
Two bridged purine dinucleosides, bis(2-N-acetyl-6-N-alkylylene-2,6-diaminopurine-2',3',5'-triacetyl-beta-D-ribofuranoside), were synthesized fi om the reaction of the key medium 3, 2-acetylamino-6-[1-(1,2,4-triazolyl...
关键词:PPM DMSO 亚砜 CL The Synthesis of Bridged Purine Dinucleoside 
MICELLAR ELECTROKINETIC CAPILLARY CHROMATOGRAPHIC SEPPATION OF PYRIMIDINE AND PURINE DERIVATIVES
《Chinese Chemical Letters》1996年第4期347-350,共4页Zhou Bin YUAN yong CHEN Ping REN Feng Mei HAN(The Graduate School,USTC.Academia Sinica, beijing 100039) 
The retention behaviours of 12 purine and pyrimidine derivatives thymine,uracil,cytosine,adenine,guanine,xanthine,hypoxanthine, purine, 4,6 diaminopyrimidine,tpeophylline,trimethoprimum and 6 (benzylamino)purine...
THE SYSTHESIS OF GANODER PURINE被引量:1
《Chinese Chemical Letters》1995年第8期661-662,共2页
The newly isolated purine alkaloid,an open chain nucleoside-ganoderpurine natural product, was synthesized by the Michael addition of adenine to mesityl oxide.
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