the National Natural Science Foundation of China(Nos.22371007,22071005);the Peking University Medicine Fund for world's leading discipline or discipline clusterdevelopment(BMU2022DJXK002).
A mild and practical method for synthesizing fluorinated quinoline derivatives,which have a wide range of applications in pharmaceuticals,materials,and organic synthesis,was described through C—F bond insertion into ...
the deanship of scientific Research at Princess Nourah bint Abdulrahman University through the Fast-track Research Funding program。
Quinolone has a broad spectrum of synthetic antibiotics with a strong therapeutic effect and quinolone is a term used for chemical treatments used to treat a powerful bacteria.Quinolones are divided into 4 generations...
Supported by the Natural Science Foundation of Henan Province,China(No.0611033400)
A shake-flask method was used to determine 1-octanol/water partition coefficients of ofloxacin, norfloxacin, lomefloxacin, ciprofloxacin, pefloxacin and pipemidic acid from 293.15 K to 323.15 K. The results show that ...
7-[4-(Aminomethyl)-3-(methoxyimino)pyrrolidin- 1-yl]- 1-cyclopropyl-6-fluoro-8-difluoromethoxy- 1,4-dihydro-4-oxoquino- line-3-carboxylic acid and its analogues have been prepared and evaluated for antibacterial a...
New quinolone derivatives of 7-[2-aminomethylaziridin-l-yl]quinolone-3-carboxylic acids were synthesized. The structures of these compounds were characterized by IH NMR and HRESI-MS.
New quinolone derivatives of 7-[(2S, 4R)-2-aminomethyl-4-hydroxypyrrolidin-1-yl] quinolone-3-carboxylic acids were synthesized by condensation of 7-halo substituted quinolone- 3-carboxylic acids with (2S, 4R)-2-aminom...
This work was supported by the National Natural Science Foundation of China (No. 39900183; No. 30171092)
Objective: To study the active sites of podophyllotoxin derivatives. Methods: Some podophyllotoxin derivatives were analyzed by quantum and mechanics method. Results: Some information was given according to the calcul...