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financial support from the National Natural Science Foundation of China(No.32072445);the Science and Technology Plan Project of Guizhou Province(Qiankehezhicheng[2024]the general 083);the Program of Introducing Talents to Chinese Universities(No.D20023);the Central Government Guides Local Science and Technology Development Fund Projects(Qiankehezhongyindi(2023)001);Key Agricultural Technology R&D Projects of the Xinjiang Production and Construction Corps(NYHXGG,2023AA602);the Frontiers Science Centre for Asymmetric Synthesis and Medicinal Molecules,Department of Education,Guizhou Province[Qianjiaohe KY(2020)004];the specific research fund of The Innovation Platform for Academicians of Hainan Province(No.SQ2020PTZ0009);。
Pyrrole is a heterocycle with four carbon atoms and a nitrogen atom,which is extensively used in the pesticide and pharmaceutical industries.In addition,it has a series of analogs such as pyrrolidine,pyrroline,and pyr...
The work was supported by the Science and Technology Projects in Guangzhou(No.202201010484)。
Codonopsis pilosula(CP),a well-known food medicine homology plant,is commonly used in many countries.In our preliminary study,a series of pyrrolidine alkaloids with high MS responses were detected as characteristic ab...
Atomically precise gold cluster catalysts have emerged as a new frontier in catalysis science,owing to their unexpected catalytic properties.In this work,we explore the evolution of the catalytic activity of clusters ...
A novel class of aminopyrrolidinyl phosphonates was synthesized in 74% - 80% isolated yield by the addition of three-fold excess of primary amines to diethyl 4-chloro-1-butynylphosphonates. The reaction was carried ou...
supported by the National Natural Science Foundation of China(21773051,21702211,21703051);Zhejiang Provincial Natural Science Foundation of China(LZ18B020001,LQ19B040001,LY18B020013);the Hangzhou Science and Technology Bureau of China(20180432B05)。
The catalytic asymmetric synthesis of novel and chiral amino acid derivatives with unconventional chemo-,diastereo-,and enantio-selectivity remains a paramount challenge.Herein we reported a novel protocol for the use...
the National Natural Science Foundation of China(No.U1732146,No.21273083);the Project under Scientific and Technological Planning Grant(No.201805010002)by Guangzhou City.
Pyrrolidine,a five membered heterocyclic molecule,is widely existing in organism.Herein,infrared spectra of pyrrolidine monomer in neutral and cationic states were obtained by vacuum ultraviolet ionization,infrared ph...
Department of Applied Chemistry,Faculty of Science,University of Johannesburg for providing chemicals and running cost for this project through the National Research Foundation(NRF)
Antibacterial resistance is a source of great concern in the effective prevention and treatment of infections caused by bacteria,making the development of requisite therapeutics a major challenge.N-(Nitrophenyl)cycloa...
Objective: To evaluate the antioxidant, immunomodulatory and anti-inflammatory activities of pyrrolidine dithiocarbamate and saxagliptin in rats with thioacetamide-induced ulcerative colitis. Methods: Animals were ora...
supported by the Project of Discovery, Evaluation and Transformation of Active Natural Compounds, Strategic Biological Resources Service Network Programme of Chinese Academy of Sciences(No. ZSTH-006);the National Natural Science Foundation of China(Nos. 21372215 and 21772192);Chinese Academy of Sciences(No.KFJ-SW-STS-143-1)
An effective and facile method for the synthesis of N-alkylated hydroxylpyrrolidine and hydroxylpiper- idine is described, A number of N-alkyl substituted iminosugars were prepared using iodine-induced intramolecular ...
financial support from the National Natural Science Foundation of China (No. 21262022)
An intramolecular organocatalytic enantioselective aza-Michael reaction of carbamates, sulfonamides and acetamides to a,b-unsaturated ketones was developed. This process is promoted by 9-amino-9-deoxy-epi-quinine and ...