Objective To examine the relationship between Tpeak- Tend interval (Tpe) and Tpe/QT ratio with occurrence of ventricular premature beats (VPBs) and left ventricular remodeling in hypertension. Methods A total of 5...
Ventricular tachy-arrhythmias are the commonest cause of sudden cardiac death in patients with ischemie heart dis- ease. It is estimated that up to 20% patients with acute myocardial infarction suffer from these arrhy...
Brugada syndrome is a primary electrical disorder of theheart, predisposing affected individuals to potentially lethal,ventricular tachy-arrhythmias. A number of mechanismshave been identified as being important incre...
Brugada syndrome is a primary arrhythmia syndrome characterized by loss-of-function mutations in the SCN5A gene, which encodes for the cardiac Na^+ channel. In affected individuals, the risk of developing malignant v...
Sudden cardiac death (SCD) affects approximately 800,000 individuals per annum globally. It is most frequently due to cardiac tachy-arrhythmias, which include mono-morphic or polymorphic ventricular tachycardia (VT...
We read the article written by Nuis, et al. The authors investigated the effects of transcatheter aortic valve implantation (TAVI) on corrected QT dispersion (cQTD) in severe aortic stenosis patients. They conclud...
grants obtained from the National Natural Science Foundation of China (No.: 81170177, 81030002) and science and Technology De- partment of Gansu Province Project (145RJZ104).
Objectives To evaluate the association between a KCNQ 1 mutation, R259H, and short QT syndrome (SQTS) and to explore the elec- trophysiological mechanisms underlying their association. Methods We performed genetic s...
the National Natural Science Foundation of China (No.30770879,30370573)
Background and Objective Increased transmural dispersion ofrepolarization (TDR) has been shown to contribute to initiation and maintenance of ventricular arrhythmia in long QT syndromes (LQTS).Intercellular uncoupling...