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Daratumumab improves the hematological response and kidney function of patients with light chain deposition disease
《Chinese Medical Journal》2025年第2期246-248,共3页Xin Zhang Xiaojuan Yu Suxia Wang Yujun Dong Minghui Zhao Fude Zhou 
supported by grants from the National High Level Hospital Clinical Research Funding(Scientific Research Seed Fund of Peking University First Hospital)(No.2022SF37);National High Level Hospital Clinical Research Funding(No.2022CR07);National Natural Science Foundation of China(No.82070747);CAMS Innovation Fund for Medical Sciences(No.2019-I2M-5-046).
To the Editor:Light chain deposition disease(LCDD)is a rare systemic complication of plasma cell disorders that primarily affects the kidneys,and LCDD can lead to chronic kidney failure.[1]Before the development of no...
关键词：chronic kidney failure Kidney Function plasma cell disorders Daratumumab BORTEZOMIB proteasome inhibitor Hematological Response chain deposition disease lcdd 
Durable natural killer cell response after three doses of SARS-CoV-2 inactivated vaccine in HIV-infected individuals
《Chinese Medical Journal》2023年第24期2948-2959,共12页Xiaodong Yang Xiuwen Wang Xin Zhang Haifeng Ding Hu Wang Tao Huang Guanghui Zhang Junyi Duan Wei Xia Bin Su Cong Jin Hao Wu Tong Zhang 
supported by grants from the National Natural Science Foundation of China(Nos.82272319 and 82072271);Beijing Natural Science Foundation(No.L222068);the High-Level Public Health Specialized Talents Project of Beijing Municipal Health Commission(Nos.2022-2-018 and 2022-1-007);the Climbing the peak(Dengfeng)Talent Training Program of Beijing Hospitals Authority(No.DFL20191701);the Beijing Health Technologies Promotion Program(No.BHTPP202002);Scientific Research Project of Beijing Youan Hospital-CCMU 2022(No.BJYAYY-YN-2022-18);Beijing Key Laboratory for HIV/AIDS Research(No.BZ0089)
Background:Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)vaccine can induce a potent cellular and humoral immune response to protect against SARS-CoV-2 infection.However,it was unknown whether SARS-CoV-2 ...
关键词：HIV SARS-CoV-2 inactivated vaccine COVID-19 Omicron variant NK cell response Immunologic memory 
Associations of toluidine red unheated serum test response to the treatment of syphilis in pregnancy and congenital syphilis: a 10-year real-world study被引量：2
《Chinese Medical Journal》2022年第13期1563-1569,共7页Jin Wei Mengyao Pang Wenhui Lun 
supported by a grant from the Beijing Scienceand,Technology Planningprojects(No.Z181100001718140).
Background: So far, there is a paucity of real-world data on the syphilis serological responses to the first-line treatment during pregnancy, and there is no relevant study on the necessity of anti-syphilis treatment ...
关键词：SYPHILIS Pregnant syphilis Toluidine red unheated serum test(TRUST) 
Body mass index is a promising predictor of response to oral rehydration saline in children with vasovagal syncope被引量：3
《Chinese Medical Journal》2021年第4期463-468,共6页Chun-Yan Tao Selena Chen Xue-Ying Li Chao-Shu Tang Jun-Bao Du Hong-Fang Jin 
This work was supported by grants from the Peking University Medicine Fund of Fostering Y oung Scholars'Scientifie&Technological Innovation,Peking University Clinical Medicine Plus X-Young Scholars Project(PKU2019LCXQ011);the Peking University Clinical Scientist Program(No.BMU2019LCKXJ001)and the Fundamental Research Funds for the Central Universities.
Background:Vasovagal syncope(VVS)greatly impairs quality of life.The therapeutic efficacy of oral rehydration saline(ORS)for unselected VVS patients is not satisfactory due to the diverse mechanisms of the disease.Bod...
关键词：Vasovagal syncope Oral rehydration saline Body mass index Therapeutic response 
Glucose-6-phosphate isomerase is associated with disease activity and declines in response to infliximab treatment in rheumatoid arthritis被引量：2
《Chinese Medical Journal》2020年第8期886-891,共6页Jing Xu Xiao-Ying Zhang Ru Li Jing Liu Hua Ye Xue-Wu Zhang Zhan-Guo Li 
This study was supported by grants from the National Natural Science and Foundation of China(Nos.81701598 and 31240023);Beijing Municipal Science and Technology Project(No.Z171100000417007)。
Background:Rheumatoid arthritis (RA), a systemic autoimmune disease characterized by synovial inflammation, can cause cartilage and bone damage as well as disability. The aim of this study was to explore whether serum...
关键词：Glucose-6-phosphate isomerase Rheumatoid arthritis TREATMENT 
Durable response to olaparib in pancreatic duct adenocarcinoma with deleterious ARID1A mutation
《Chinese Medical Journal》2019年第24期3012-3014,共3页Xue-Song Zhao Jing Zhou Lei Dong Hui Zhang Ying-Jiang Ye 
This work has been supported by a grant from the National Natural Science Foundation of China(No.81572379).
To the Editor:Pancreatic cancer is one of the leading causes of cancer death worldwide.The significant symptoms prompting diagnosis often appear once the tumor invades surrounding tissues or metastasizes,resulting in ...
关键词：ARID1A DIAGNOSIS ADENOCARCINOMA 
Repetitive Nerve Stimulation in Amyotrophic Lateral Sclerosis被引量：8
《Chinese Medical Journal》2018年第18期2146-2151,共6页Xiao-Sun Sun Wen-Xiu Liu Zhao-Hui Chen Li Ling Fei Yang Hong-Fen Wang Fang Cui Xu-Sheng Huang 
This study was supported by grants from the National Natural Science Foundation of China （No. 81671278 and No. 81601096）, One Hundred Advantage Projects ＂Fund of Chinese PLA General Hospital＂ （No. YS201415）, and Key Research and Development Plan of Hainan Province （No. ZDFY2016120）.
Background： Nowadays, it is widely known that decremental responses in low-frequency repetitive nerve stimulation （LF-RNS） are frequently observed in patients with amyotrophic lateral sclerosis （ALS）. The patholo...
关键词：Amyotrophic Lateral Sclerosis Decremental Response Dying Back Repetitive Nerve Stimulation 
Differences of Matrix Metalloproteinase 2 Expression between Left and Right Ventricles in Response to Nandrolone Decanoate and/or Swimming Training in Mice
《Chinese Medical Journal》2018年第2期207-212,共6页Ying Bai Xu-Bo Shi Yu-Qiong Zhang Yue-Li Wang Xin-Yao Liu Maria Asuncion Esteve-Pastor 
Background： Matrix metalloproteinase （MMP）-2 plays an important role in the remodeling of left ventricles （LVs） and right ventricles （RVs）. We investigated the differences of MMP-2 expression between LV and RV ...
关键词：FIBROSIS Matrix Metalloproteinase 2 Nandrolone Decanoate Swimming Training 
Postherpetic Comedones in Two Chinese Han Patients被引量：2
《Chinese Medical Journal》2017年第13期1615-1616,共2页Bo Wang Jie Zheng Hong-Wei Wang 
This work is Supported by a grant from the National Natural Science Foundation of China （No. 81572671 ）.
Wolf＇s postherpetic isotopic response （PHIR） describes the occurrence of a new lesion at the site of a healed herpetic lesion. It is more commonly seen alter infection by varicella-zoster virus （VZV） than herpes ...
关键词：Comedone Herpes Zoster Wolf＇s Postherpetic Isotopic Response 
Collapsin Response Mediator Protein-2-induced Retinal Ischemic Injury in a Novel Mice Model of Ocular Ischemia Syndrome被引量：3
《Chinese Medical Journal》2017年第11期1342-1351,共10页Yu Wang Xiao-Lei Wang Guo-Li Xie Hong-Yang Li Yan-Ling Wang 
Background： Collapsin response mediator protein-2 （CRMP2） has been shown to be involved in ischemia/hypoxia （IH） injury. We determined whether CRMP2 modulates ischemic injury in the retinal of Ocular ischemic syn...
关键词：Calpeptin Collapsin Response Mediator Protein 2 Ischemia Injury Ocular Ischemic Syndrome PHOSPHORYLATION 
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