Objective To investigate the efficacy and safety of liposomal amphotericin B(L-AmB)for the salvage treatment of invasive fungal disease(IFD)in patients withhematologicaldiseases.MethodsDatawere retrospectively collect...
the financial supports of the National Science and Technology Major Projects for"Major New Drugs Innovation and Development"(2018ZX09711003-001-001)of China.
Ricin is a highly toxic type 2 ribosome-inactivating protein(RIP)which is extracted from the seeds of castor beans.Ricin is considered a potential bioterror agent and no effective antidote for ricin exists so far.In t...
supported by the National Key Research and Development Program of China (2017YFC0505202);Strategic Priority Research Program of Chinese Academy of Sciences (XDB31000000);the National Natural Science Foundation of China (31722049, 31772434);Key Research Program of Frontier Sciences, CAS (QYZDB-SSW-SMC058);the Southeast Asia Biodiversity Research Institute, Chinese Academy of Science (Y4ZK111B01);the Youth Innovation Promotion Association of CAS;the CAS “Light of West China” Program (2018XBZG_JCTD_001);Talent Program from Organization Department of Sichuan Provincial Committee;partially supported by project BSTMV.08/16-19 to NTT
The single prefrontal configuration has historically been used as an important diagnostic character for many natricine taxa. For example, the genus Trimerodytes Cope, 1895 was long been regarded as a junior synonym of...
Ricin is one of the most feared bioweapons in the world due to its extreme toxicity and easy access. Since no anti- dote exists, it is of paramount importance to identify the pathways underlying ricin toxicity. Here, ...
Supported by the National Natural Science Foundation of China(No.21402114).
Amphotericin B(AmB) has been widely used in antifungal therapy. AraB molecules combine with cholesterol to form pores that can be toxic to human cells, thus greatly limiting its clinical application. The interaction...
This work was supported by the grants from the Modern Agricultural Industrial Technology System (No. CARS-22-ZJ0202), Zhejiang Sericultural Sci-Tech Innovation Team (No. 2011R50028), and the National Natural Science Foundation of China (No. 31302033).
Nosema bombycis is an obligate intracellular parasitic fungus that utilizes a distinctive mechanism to infect Bombyx mori. Spore germination can be used for host cell invasion; however, the detailed mechanism remains ...