supported by the National Natural Science Foundation of China(No.NSFC 32170820);the National Key R&D Program of China(No.2022YFC2702704);the Program for HUST Academic Frontier Youth Team.
In mammalian cells,the nucleolus serves as a factory for organizing ribosomal RNA(rRNA)synthesis and ribosomal biogenesis.Moreover,by interacting with rRNA genes and heterochromatin,nucleolus also functions in chromat...
RNA修饰广泛存在于所有主要RNA类别(包括信使RNA、转运RNA和核糖体RNA)中,核糖体RNA(ribosomal RNA,rRNA)因其刚性的结构,为使用冷冻电镜(Cryogenic electron microscopy,Cryo-EM)技术探讨RNA修饰的结构与功能之间的关系提供了一个理想...