SPARFLOXACIN

作品数:15被引量:13H指数:2
导出分析报告
相关领域:医药卫生更多>>
相关作者:屠曾宏欣坚马小超李俊岭张婷更多>>
相关机构:中国科学院上海生命科学研究院华西医科大学附属第一医院北京医科大学更多>>
相关期刊:《中国麻风皮肤病杂志》《American Journal of Analytical Chemistry》《四川生理科学杂志》《Acta Pharmacologica Sinica》更多>>
相关基金:国家自然科学基金更多>>
-

检索结果分析

结果分析中...
条 记 录,以下是1-10
视图:
排序:
Pulse radiolysis of sparfloxacin in neutral aqueous solution被引量:2
《Nuclear Science and Techniques》2013年第B12期63-66,共4页LIU Yancheng LI Haixia CUI Rongrong TANG Ruizhi XU Yulie WANG Wenfeng 
Supported by National Natural Science Foundation of China (No. 21173252).
关键词:司帕沙星 脉冲辐解 中性水溶液 阴离子自由基 阳离子自由基 瞬态吸收光谱 水合电子 速率常数 
Simple and sensitive determination of sparfloxacin in pharmaceuticals and biological samples by immunoassay被引量:2
《Journal of Pharmaceutical Analysis》2012年第3期214-219,共6页Hua-Jin Zenga,Ran Yangb,Bing Liub,Li-Fang Leib,Jian-Jun Lib,Ling-Bo Qub,c,n aSchool of Pharmaceutical Sciences,Zhengzhou University,Zhengzhou 450001,China bDepartment of Chemistry,Zhengzhou University,Zhengzhou 450001,China cSchool of Chemistry & Chemical Engineering,Henan University of Technology,Zhengzhou 450001,China 
Plasma quinolone concentrations are not routinely measured in clinical practice.However,in order to optimize quinolone treatment,monitoring of plasma concentrations could sometimes be useful particularly in critically...
关键词:SPARFLOXACIN Enzyme-linked immunosorbent assay(ELISA) Biological samples PHARMACOKINETICS Tissue distribution 
New Method for Optimization and Simultaneous Determination of Sparfloxacin and Non Steroidal Anti-Inflammatory Drugs: Its <i>In-Vitro</i>Application被引量:6
《American Journal of Analytical Chemistry》2012年第4期328-337,共10页Somia Gul Najma Sultana Muhammad Saeed Arayne Sana Shamim Mahwish Akhtar 
A simple reversed phase HPLC method was developed and validated for the simultaneous determination of sparfloxacin (SPFX), diclofenac sodium, meloxicam, ibuprofen, flurbiprofen, naproxen and mefenemic acid in a relati...
关键词:SPARFLOXACIN NSAIDS HPLC INTERACTIONS ANOVA 
Studies on Reaction Mechanism Between Sparfloxacin and Bovine Serum Albumin
《Chemical Research in Chinese Universities》2004年第1期81-87,共7页GUOMing ZOUJian-wei YIPing-gui SHANGZhi-cai HUGui-xiang YUQing-sen 
SupportedbytheNationalNaturalScienceFoundationofChina(No .2 0 1730 5 0 )
The binding of sparfloxacin and bovine serum albumin(BSA) in aqueous solution was studied by means of fluorescence and absorbance spectra, and the interactions influenced by Fe 3+ and Cu 2+ were explored. Based ...
关键词:SPARFLOXACIN Bovine serum albumin Fluorescence spectroscopy 
Reliability of phototoxic tests of fluoroquinolones in vitro被引量:2
《Acta Pharmacologica Sinica》2003年第5期453-459,480,共8页张婷 李俊岭 马小超 欣坚 屠曾宏 
AIM: To make sure the reliability of phototoxic tests in vitro by comparing the phototoxic potential of 4 fluoroquinolones(FQ). METHODS: Lomefloxacin (LFLX), sparfloxacin (SPFX), ciprofloxacin (CPFX), and norfloxacin ...
关键词:PHOTOTOXICITY FLUOROQUINOLONES LOMEFLOXACIN SPARFLOXACIN 
Determination of Sparfloxacin in Human Urine by Reversed-Phase High Performance Liquid Chromatography With Nitrous Acid and Hydroiodic Pre-Column Derivatization被引量:1
《Chinese Chemical Letters》2001年第11期1007-1010,共4页Li Ming DU Zhe Feng FAN Jin Li QIAO Jing Ping WANG 
Sparfloxacin can be oxidized by nitrous acid, then react with hydroiodic acid to form a fluorescent derivative. Based on this, a reversed-phase high performance liquid chromatographic pre-column derivatization new met...
关键词:SPARFLOXACIN HPLC pre-column derivatization human urine 
Study on Fluorescence Property of Sparfloxacin Derivatizing System and its Application被引量:1
《Chinese Chemical Letters》2000年第3期255-258,共4页Du, LM Zhou, J Xu, QQ Fan, ZF Yuan, R 
In acid medium, sparfloxacin is oxidized by nitrous acid, then reacts with hydrobromic acid to form a new fluorescence substance, which can emit the strong fluorescence. which is 151 fold more than that of sparfloxaci...
关键词:SPARFLOXACIN nitrous acid derivative-synchronous fluorescence human urine 
Sparfloxacin与lomefloxacin随机对照治疗81例呼吸系统感染临床评价
《四川生理科学杂志》1999年第4期39-39,共1页吕晓菊 裘雁秋 冯萍 刘自贵 张慧琳 周志强 俞汝佳 朱淑媛 
目的:用司帕沙星与洛美沙星随机对照治疗急性呼吸系统细菌性感染,对前者进行安全性及有效性评价。方法:剂量为司帕沙星200mg,QD,疗程5-14天,洛美沙星200mg,Bid,餐后1小时服用,疗程5-14天。结果:共完成81例(试验组41例,对照组40例),病种...
关键词:呼吸系统感染 随机对照治疗 司帕沙星 洛美沙星 支气管扩张症 医科大学 急性细菌性感染 安全性及有效性 试验组 周围脓肿 
1997年新药
《德国临床用药》1998年第2期15-20,共6页Hein.,S 
从1996年12月至1997年11月,差不多有40个新药上市(表)-比往年较多。大多是抗血压剂和细胞抑制剂。新的治疗原理,比如有COMT抑制剂Tolcapon用于治疗帕金森病患者,前列腺素衍生物Latanoprost...
关键词:新药 GREPAFLOXACIN SPARFLOXACIN 97年 分类 
SPARFLOXACIN正常人体耐受性及药代动力学研究
《四川生理科学杂志》1998年第4期38-38,共1页李华 高磊 李耘 李家泰 
本研究对日产sparfloxacin进行了100mg、200mg、300mg和400mg四个剂量的耐受性试验,100mg、200mg、400mg三个剂量的药代动力学试验。耐受性试验结果表明直至400mg试验结束不论是受试者主观感觉,还是血、尿生化指标均无改变。证明单次口...
关键词:药代动力学 耐受性试验 正常人体 动力学试验 动力学参数 临床药理研究 尿生化指标 北京医科大学 药物浓度 SPAR 
检索报告 对象比较 聚类工具 使用帮助 返回顶部