PHOTOTOXICITY

作品数：15被引量：35H指数：4
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相关领域：医药卫生更多>>
相关作者：屠曾宏欣坚马小超李俊岭张婷更多>>
相关机构：中国科学院上海生命科学研究院北京工业大学更多>>
相关期刊：《IMP & HIRFL Annual Report》《Acta Oceanologica Sinica》《Journal of Environmental Sciences》《World Journal of Experimental Medicine》更多>>
相关基金：国家自然科学基金国家教育部博士点基金湖北省自然科学基金国家重点基础研究发展计划更多>>
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Red-emissive carbon quantum dots minimize phototoxicity for rapid and long-term lipid droplet monitoring
《Chinese Chemical Letters》2024年第10期341-347,共7页Fengkai Zou Borui Su Han Leng Nini Xin Shichao Jiang Dan Wei Mei Yang Youhua Wang Hongsong Fan 
supported by the National Natural Science Foundation of China(Nos.52003178,52273141 and 51973132);Natural Science Foundation of Sichuan Province(No.2023NSFSC0338)。
Long-term fluorescence monitoring of subcellular organelles is crucial for cellular physiology and pathology studies.Lipid droplets(LDs)are increasingly recognized for their involvement in various biological processes...
关键词：Carbon quantum dots SOLVATOCHROMISM Lipid droplet probe Fluorescence imaging Wash-free 
Light sheet fluorescence microscopy: Advancing biological discovery with more dimensions, higher speed, and lower phototoxicity
《The Innovation》2024年第5期29-30,共2页Yao Zhou Shiqi Mao Peng Fei 
supported by the National Key Research and Development Program of China(2022YFC3401102);the National Natural Science Foundation of China(T2225014 and 21927802);the Fundamental Research Funds for the Central Universities(YCJJ20242110);the Postdoctoral Fellowship Program of CPSF under grant number GZB20240246.
TO SEE THE WORLD IN A GRAIN OF SAND.Fluorescence microscopy has proved to be essential for seeing life in a grain of a cell.Classic epifluorescence microscopes,such as wide-field microscopes and laser scanning confoca...
关键词：fluorescence DIMENSIONS FIGURE 
Meso-substituted cationic 3-and 4-N-Pyridylporphyrins and their Zn(II)derivatives for antibacterial photodynamic therapy被引量：2
《Journal of Innovative Optical Health Sciences》2022年第1期1-16,共16页Aram G.Gyulkhandanyan Marina H.Paronyan Anna G.Gyulkhandanyan Karapet R.Ghazaryan Marina V.Parkhats Boris M.Dzhagarov Maria V.Korchenova Ekaterina N.Lazareva Elena S.Tuchina Grigor V.Gyulkhandanyan Valery V.Tuchin 
the Decree of the Government of the Russian Federation No.220 of April 9,2010(Agreement No.075-15-2021-615 of June 4,2021).
Photodynamic inactivation of microorganisms known as antibacterial photodynamic therapy(APDT)is one of the most promising and innovative approaches for the destruction of pathogenic microorganisms.Among the photosensi...
关键词：Antibacterial photodynamic therapy cationic porphyrins/metalloporphyrins PHOTOTOXICITY Zn-metalloporphyrins singlet oxygen quantum yield Gram negative and Gram positive bacteria S.aureus MRSA E.coli Salmonella typhimurium. 
Effects of N-1 substituent on the phototoxicity of fluoroquinolone antibiotics: comparison of pefloxacin and difloxacin被引量：1
《Nuclear Science and Techniques》2020年第7期34-45,共12页Jian-Feng Zhao Yan-Cheng Liu Yu-Lie Xu Wen-Feng Wang 
supported by the National Natural Science Foundation of China(No.21173252)。
The photophysics and photochemistry of pefloxacin(PEF),a 1-ethyl-substituted fluoroquinolone(FQ)antibiotic,were studied using transient,steady-state experimental methods and computational methods.The fundamental photo...
关键词：SUBSTITUENT TRANSIENT PHOTOCHEMISTRY 
Connexin 40-formed GJIC increases the phototoxicity of photodynamic therapy through ROS-and calcium-mediated pathways
《中国药理学与毒理学杂志》2017年第10期1026-1027,共2页Deng-pan WU Li-ru BAI Jin-lan HUANG 
supported by National Natural Science Foundation of China(81402946);Initializing Fund of Xuzhou Medical University of China(D2014017 and D2014010);Natural Science Research Grant of Higher Education of Jiangsu Province of China(14KJD310002)
OBJECTIVE To explore the effect of connexin(Cx)40-formed gap junctional intercellular communication(GJIC)on Photofrin-photodynamic therapy(PDT)phototoxicity in Cx40-transfected He La cells and its potential mechanisms...
关键词：photodynamic therapy gap junctional intercellular communication connexin40 PHOTOTOXICITY 
4-71 Inuence of Phototoxicity of the Live Cell Imaging System at IMP Microbeam Facility
《IMP & HIRFL Annual Report》2016年第1期198-199,共2页Liu Wenjing Guo Jinlong Wu Ruqun Wei Junzhe Chen Hao Li Yaning Zhao Jing Li Xiaoyue Du Guanghua 
To investigate the spatiotemporal dynamics of DNA damage and repair after particle irradiation,an online live cell imaging system has been established based on the microbeam facility at Institute of Modern Physics(IMP...
Assessing the effects of surface-bound humic acid on the phototoxicity of anatase and rutile TiO_2 nanoparticles in vitro被引量：7
《Journal of Environmental Sciences》2016年第4期50-60,共11页Xiaojia He Sabrieon Sanders Winfred G.Aker Yunfeng Lin Jessica Douglas Huey-min Hwang 
supported in part by the NSF-REU program(National Science Foundation-Research Experiences for Undergraduates,No.#CHE-1156111);the NSF-CREST program(National Science Foundation-Centers of Research Excellencein Science and Technology,No.#HRD-0833178)
In this study,the cytotoxicity of two different crystal phases of TiO2 nanoparticles,with surface modification by humic acid（HA）,to Escherichia coli,was assessed.The physicochemical properties of TiO2 nanoparticles ...
关键词：TiO2nanoparticles Escherichia coli Humic acid Crystallinity Surface coating 
Lipofuscins prepared by modification of photoreceptor cells via glycation or lipid peroxidation show the similar phototoxicity被引量：2
《World Journal of Experimental Medicine》2016年第4期63-71,共9页Alexander Dontsov Anna Koromyslova Mikhail Ostrovsky Natalia Sakina 
The Russian Foundation for Basic Research,No.15-29-03831
AIM To investigate the effect of two ways of lipofuscin production(lipid peroxidation and glycation) on lipofuscin fluorescence characteristics and phototoxicity and to compare them with the properties of natural lipo...
关键词：Model lipofuscins Retinal PIGMENT EPITHELIUM PHOTORECEPTOR outer SEGMENTS Bisretinoids Glycation Lipid PEROXIDATION Superoxide 
Photosafety testing of dermally-applied chemicals based on photochemical and cassette-dosing pharmacokinetic data
《Asian Journal of Pharmaceutical Sciences》2016年第1期237-238,共2页Hiroto Ohtake Yukiko Suzuki Masashi Kato Yoshiki Seto Satomi Onoue 
Drug-induced phototoxicity is elicited by exposure of skin and/or eyes to topical or systemic administration of chemicals,followed by exposure to sunlight.For photosafety testing,a new screening strategy,employing in ...
关键词：Photosafety assessment PHOTOTOXICITY PHOTOREACTIVITY Pharmacokinetics 
Protective effect of saturated hydrogen saline against blue light-induced retinal damage in rats被引量：8
《International Journal of Ophthalmology(English edition)》2012年第2期151-157,共7页Mei Feng Xing-Hua Wang Xiao-Bo Yang Qing Xiao and Fa-Gang Jiang 
AIM: To explore the effect of saturated hydrogen saline on blue light-induced retinal damage in rats. METHODS: The retinal damage of rats was induced by blue light exposure for 6 hours and examined 8 hours, 16 hours a...
关键词：RETINA HYDROGEN ANTIOXIDANTS PHOTOTOXICITY 
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