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SPERMATOGENESIS: 作品数：359被引量：1218H指数：16; 导出分析报告; 相关作者：侯聪聪杨万喜何天文张祥忠张雅林更多>>; 相关机构：浙江大学广东省妇幼保健院中山大学附属第三医院绍兴文理学院更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划北京市自然科学基金中国博士后科学基金更多>>

A convenient research strategy for functional verification of epigenetic regulators during spermatogenesis: 《Asian Journal of Andrology》2025年第2期261-267,共7页Shan Li Ying Yuan Ke-Yu Zhang Yi-Dan Guo Lu-Tong Wang Xiao-Yuan Zhang Shu Zhang Qi Yan Rong Zhang Jie Chen Feng-Tang Yang Jing-Rui Li; financially supported by the Shandong Provincial Natural Science Foundation(No.ZR2021QC182).; Spermatogenesis is a fundamental process that requires a tightly controlled epigenetic event in spermatogonial stem cells(SSCs).The mechanisms underlying the transition from SSCs to sperm are largely unknown.Most stud...; 关键词：JMJD1A JMJD2C H3K9me2 SPERMATOGENESIS spermatogonial stem cell

A behind-the-scenes role of BDNF in the survival and differentiation of spermatogonia: 《Asian Journal of Andrology》2025年第1期37-43,共7页Shin-ichi Tomizawa Kazushige Kuroha Michio Ono Kuniko Nakajima Kazuyuki Ohbo; partly supported by Grant-in-Aid for Scientific Research on Innovative Areas funding from the Ministry of Education,Culture,Sports,Science,and Technology(MEXT)KAKENHI(No.22H04677 to KO);a grant from the Japan Society for the Promotion of Science KAKENHI(No.20K09543 to ST,No.20K07228 to KK,and No.19KK0183 to KO);the Takeda Science Foundation(2021 to KK).; Mouse spermatogenesis entails the maintenance and self-renewal of spermatogonial stem cells(SSCs),which require a complex web-like signaling network transduced by various cytokines.Although brain-derived neurotrophic ...; 关键词：BDNF SPERMATOGENESIS SPERMATOGONIA stem cells

Clinical manifestations and spermatogenesis outcomes in Chinese patients with congenital hypogonadotropic hypogonadism caused by inherited or de novo FGFR1 mutations: 《Asian Journal of Andrology》2024年第4期426-432,共7页Yu-Fan Yang Hai-Lu Ma Xi Wang Min Nie Jiang-Feng Mao Xue-Yan Wu; Natural Science Foundation of Beijing(grant No.7212080);National Natural Science Foundation of China(grant No.81971375);National High Level Hospital Clinical Research Funding(2022-PUMCH-D-002);CAMS Innovation Fund for Medical Sciences(CIFMS 2021-I2M-1-003);National High Level Hospital Clinical Research Funding(2022-PUMCH-C-028).; Fibroblast growth factor receptor 1(FGFR1)mutations are associated with congenital hypogonadotropic hypogonadism(CHH)through inheritance or spontaneous occurrence.We detected FGFR1 mutations in a Chinese cohort of 210...; 关键词：congenital hypogonadotropic hypogonadism de novo FGFR1 INHERITED

Pyruvate kinase M in germ cells is essential for sperm motility and male fertility but not spermatogenesis: 《Asian Journal of Andrology》2024年第2期212-219,共8页Gao-Qing Qian Xiao-Chen Wang Xi Zhang Bin Shen Qiang Liu; supported by the National Natural Science Foundation of China(No.81571488 and No.81771637).; Male germ cells employ specific metabolic pathways throughout their developmental stages.In a previous study,we discovered heightened expression of pyruvate kinase M(PKM),a pivotal glycolytic enzyme,in spermatogonia a...; 关键词：GLYCOLYSIS male fertility pyruvate kinase M sperm motility SPERMATOGENESIS

Detection and evaluation of different morphological forms of Mycoplasma hominis in human semen: 《Asian Journal of Andrology》2024年第1期71-76,共6页Elizaveta Bragina Tatyana Sorokina Avtandil Chogovadze Yulia Shevchenko Vyacheslav Chernykh Olga Barkhatova Irina Rakovskaya; Ultrastructural research supported by the Moscow State University Development Program(PNR 5.13);The present study was performed within the framework of the project Multicenter Research Bioresource Collection Human Reproductive Health,No.15.BRK.21.0008 of the Ministry of Science and Higher Education of the Russian Federation.; Recently discovered microcolonial forms of Mycoplasma hominis(M.hominis)and their impact on human spermatogenesis are studied.The spermatozoa of 125 fertile men(sperm donors;from Reprobank[Reproductive Tissue Bank,Mos...; 关键词：EJACULATE FERTILITY Mycoplasma hominis SPERMATOGENESIS transmission electron microscopy

Low XIST expression in Sertoli cells of Klinefelter syndrome patients causes high susceptibility of these cells to an extra X chromosome被引量：1: 《Asian Journal of Andrology》2023年第6期662-673,共12页Liang-Yu Zhao Peng Li Chen-Cheng Yao Ru-Hui Tian Yu-Xin Tang Yu-Zhuo Chen Zhi Zhou Zheng Li; This work was supported by grants from the National Key R&D Program of China(2022YFC2702700);National Natural Science Foundation of China(82201756 and 82171597);China Postdoctoral Science Foundation(2021M703747);GuangDong Basic and Applied Basic Research Foundation(2021A1515111109)。; Klinefelter syndrome(KS)is the most common genetic cause of human male infertility.However,the effect of the extra X chromosome on different testicular cell types remains poorly understood.Here,we profiled testicular ...; 关键词：Klinefelter syndrome nonobstructive azoospermia Sertoli cell SPERMATOGENESIS X chromosome inactivation

Characterization of the protein expression and localization of hnRNP family members during murine spermatogenesis被引量：1: 《Asian Journal of Andrology》2023年第3期314-321,共8页Xiao-Li Wang Jin-Mei Li Shui-Qiao Yuan; This work,in part,was supported by grants from the National Natural Science Foundation of China(31801237 to XLW and 82171605 to SQY);the Science Technology and Innovation Commission of Shenzhen Municipality(JCYJ20170818160910316 to SQY).; Mammalian testis exhibits remarkably high transcriptome complexity,and spermatogenesis undergoes two periods of transcriptional cessation.These make the RNA-binding proteins(RBPs)the utmost importance during male germ...; 关键词：gene expression heterogeneous nuclear ribonucleoproteins MICE Sertoli cells SPERMATOGENESIS

Loss-of-function CFTR p.G970D missense mutation might cause congenital bilateral absence of the vas deferens and be associated with impaired spermatogenesis被引量：1: 《Asian Journal of Andrology》2023年第1期58-65,共8页Jian-Wen Hou Xiao-Liang Li Li Wang Cong-Ling Dai Na Li Xiao-Hui Jiang Yue-Qiu Tan Er-Po Tian Qin-Tong Li Wen-Ming Xu; support from the National Key Research and Developmental Program of China (No.2018YFC1003603);the National Natural Science Foundation of China (No.81971445).; Congenital bilateral absence of the vas deferens(CBAVD)is observed in 1%–2%of males presenting with infertility and is clearly associated with cystic fibrosis transmembrane conductance regulator(CFTR)mutations.CFTR i...; 关键词：AZOOSPERMIA congenital bilateral absence of the vas deferens CFTR mutation male infertility SPERMATOGENESIS

Identification of risk genes in Chinese nonobstructive azoospermia patients based on whole-exome sequencing被引量：2: 《Asian Journal of Andrology》2023年第1期66-72,共7页Yu-Jun Liu Xin-Jie Zhuang Jian-Ting An Hui Jiang Rong Li Jie Qiao Li-Ying Yan Xu Zhi; supported by grants from the National Natural Science Foundation of China (No.81971440);the Beijing Natural Science Foundation (No.7212129).; Nonobstructive azoospermia(NOA)is a severe condition in infertile men,and increasing numbers of causative genes have been identified during the last few decades.Although certain causative genes can explain the presenc...; 关键词：cystic fibrosis transmembrane conductance regulator nonobstructive azoospermia potential risk genes SPERMATOGENESIS whole-exome sequencing

RNAs in the testicular tissue of patients with non-obstructive azoospermia被引量：1: 《Asian Journal of Andrology》2022年第6期660-665,共6页Zhe Zhang Han Wu Lin Zheng Hai-Tao Zhang Yu-Zhuo Yang Jia-Ming Mao De-Feng Liu Lian-Ming Zhao Hui Liang Hui jiang; supported by the National Natural Science Foundation of China(No.81901535,No.82071698);the National Key Research and Developmental Program of China(No.2021YFC2700203);the Natural Science Foundation of Beijing Municipality(No.722208).; Circular RNAs(circRNAs)are highly conserved and ubiquitously expressed noncoding RNAs that participate in multiple reproductionrelated diseases.However,the expression pattern and potential functions of circRNAs in the...; 关键词：circular RNA MICROARRAY non-obstructive azoospermia SPERMATOGENESIS testicular tissue

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