The Fundamental Research Funds for the Central Universities,Grant/Award Number:E1E43201X2;The Beijing Municipal Natural Science Foundation,Grant/Award Number:Z200021;The CAS Interdisciplinary Innovation Team,Grant/Award Number:JCTD-2020-04;The National Key Research and Development Program of China,Grant/Award Numbers:2021YFE0201100,2022YFA1103401;The National Natural Science Foundation of China,Grant/Award Number:31872839。
Sperm development is critical for male reproductive capability;any disruption during the process of spermatogenesis will result in male infertility.In this research,we used the C-Nap1 encoded by the gene of Cep250 kno...
partly supported by Grant-in-Aid for Scientific Research on Innovative Areas funding from the Ministry of Education,Culture,Sports,Science,and Technology(MEXT)KAKENHI(No.22H04677 to KO);a grant from the Japan Society for the Promotion of Science KAKENHI(No.20K09543 to ST,No.20K07228 to KK,and No.19KK0183 to KO);the Takeda Science Foundation(2021 to KK).
Mouse spermatogenesis entails the maintenance and self-renewal of spermatogonial stem cells(SSCs),which require a complex web-like signaling network transduced by various cytokines.Although brain-derived neurotrophic ...
funding from the Fundamental Fund,Prince of Songkla University(Contact No.SCI6405032b);funding support from the NSRF via the Program Management Unit for Human Resources&Institutional Development,Research and Innovation[grant number B05F630026];Science and Technology Research Partnership for Sustainable Development(SATREPS,Japan Science and Technology Agency(JST,JPMJSA1806)/Japan International Cooperation Agency(JICA);the Faculty of Science Research Fund,Prince of Songkla University[grant number 1-2565-02-001].
The genetic diversity of the banana shrimp Fenneropenaeus merguiensis is at risk because of over-harvesting,which consequently reduces food security.This endangerment is exacerbated because this species is not commonl...
supported by the Laoshan Laboratory(LSKJ202203204);the National Natural Science Foundation of China(32170832,32170541);the Fundamental Research Funds for Central Universities,China(202012004).
Switching from mitotic spermatogonia to meiotic spermatocytes is critical to producing haploid sperms during male germ cell differentiation.However,the underlying mechanisms of this switch remain largely unexplored.In...
This work was supported by the National Key Research and Development Program of China(No.2022YFC2702700);the National Natural Science Foundation of China(No.82171597);Clinical Research Plan of Shanghai Hospital Development Center(No.SHDC2020CR3077B).
The regulation of spermatogonial proliferation and apoptosis is of great significance for maintaining spermatogenesis.The single-cell RNA sequencing(scRNA-seq)analysis of the testis was performed to identify genes upr...
This work was supported by the Shandong Province Natural Science Foundation(ZR2020KC038);Research and Development Program of Shandong Province(2021LZGC029);National Key Research and Development Program(2018YFD0901205,2018YFD0901204);China Agriculture Research System(CARS-47).
Black rockfish(Sebastes schlegelii)is one of the most important marine economic viviparous fishes.Recently,germplasm degradation and genetic diversity reduction have occurred due to overfishing and long-term artificia...
supported by the National Key R&D Program of China(2018YFD0900301);the National Nature Science Foundation of China(31722058,31802275,31472269);the AoShan Talents Cultivation Program Supported by Qingdao National Laboratory for Marine Science and Technology(2017ASTCP-ES06);the Taishan Scholar Project Fund of Shandong of China to C.S.;the National Ten-Thousands Talents Special Support Program to C.S.;the Central Public-interest Scientific Institution Basal Research Fund,CAFS(2020TD19);the China Agriculture Research System(CARS-47-G03)。
Female-to-male sex reversals(pseudomales)are common in lower vertebrates and have been found in natural populations,which is a concern under rapid changes in environmental conditions.Pseudomales can exhibit altered sp...
supported by the National Natural Science Foundation of China(Grant No.32002178 and 31772605);the Undergraduate Training Program for Innovation and Entrepreneurship(X202110712185).
Background:Spermatogenesis is an intricate developmental process during which undifferentiated spermatogonia,containing spermatogonial stem cells(SSCs),undergo self-renewal and differentiation to generate eventually m...
supported by the National Key R&D Program of China(2018YFD0901205);National Natural Science Foundation of China(31771587,31970535);Guangdong Basic and Applied Basic Research Foundation(2020A1515010358)。
In vitro production of functional gametes can revolutionize reproduction by reducing generation intervals and accelerating genetic breeding in aquaculture,especially in fish with relatively long generations.Neverthele...
the National Natural Science Foundation of China[31902339];the Foundation for Youth Doctor of Gansu Province[2021QB-026];the Youth Talent Program of“Fuxi”[Gaufx-03Y02];the Scientific Research Start-up Funds for Openly-Recruited Doctors of Gansu Agricultural University[2017RCZX-13];the Special Funds for Discipline Construction of Gansu Agricultural University[GAU-XKJS-2018-067]。
Objective The expression patterns of ribosomal large subunit protein 23 a(RPL23 a)in mouse testes and GC-1 cells were analyzed to investigate the potential relationship between RPL23 a expression and spermatogonia apo...