supported in part by research grants from the National Institutes of Health(No.CA226303 to T.C.H.,No.DE030480 to R.R.R.).;supported in part by research grants from the 2019 Science and Technology Research Plan Project of the Chongqing Education Commission(China)(No.KJQN201900410);the 2019 Funding for Postdoctoral Research(Chongqing Human Resources and Social Security Bureau No.298);the Natural Science Foundation of China(No.82102696);supported by the Medical Scientist Training Program of the National Institutes of Health(No.T32 GM007281).
While progenitor cell-based cardiomyocyte regeneration holds great promise of repairing an injured heart,primary cardiomyogenic progenitors(CPs)have a limited life span in culture,hampering the use of CPs for in vitro...
The reported study was supported in part by research grants from the 2019 Chongqing Support Program for Entrepreneurship and Innovation(No.cx2019113)(JF);the 2019 Science and Technology Research Plan Project of Chongqing Education Commission(KJQN201900410)(JF);the 2019 Youth Innovative Talent Training Program of Chongqing Education Commission(No.CY200409)(JF);the 2019 Funding for Postdoctoral Research(Chongqing Human Resources and Social Security Bureau No.298)(JF)and the National Key Research and Development Program of China(2016YFC1000803);RRR,TCH and GAA were partially funded by the National Institutes of Health(DE030480);WW was supported by the Medical Scientist Training Program of the National Institutes of Health(T32 GM007281);This project was also supported in part by The University of Chicago Cancer Center Support Grant(P30CA014599);the National Center for Advancing Translational Sciences of the National Institutes of Health through Grant Number UL1 TR000430;TCH was also supported by the Mabel Green Myers Research Endowment Fund,The University of Chicago Orthopaedics Alumni Fund,and The University of Chicago SHOCK Fund.Funding sources were not involved in the study design;in the collection,analysis and/or interpretation of data;in the writing of the report;or in the decision to submit the paper for publication.
Skin injury is repaired through a multi-phase wound healing process of tissue granulation and re-epithelialization.Any failure in the healing process may lead to chronic non-healing wounds or abnormal scar formation.A...