TARGETED

作品数:1083被引量:3093H指数:24
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相关领域:医药卫生更多>>
相关作者:朱为宏杨敏曹宏邱星辉周可新更多>>
相关机构:华东理工大学复旦大学第四军医大学北京大学更多>>
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相关基金:国家自然科学基金中国博士后科学基金国家重点基础研究发展计划国家高技术研究发展计划更多>>
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  • 期刊=World Journal of Clinical Casesx
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Omadacycline in the treatment of scrub typhus:Three case reports被引量:1
《World Journal of Clinical Cases》2024年第25期5832-5838,共7页Xue-Mei Lang Yun Qiu Ya-Juan Jia Hong Sun Su-Min Gao Hong-Mei Zhao 
Supported by National Natural Science Foundation of China,No.81800721;the Postdoctoral Foundation of China,2020M671387.
BACKGROUND Scrub typhus is a naturally occurring acute infectious disease that is primarily transmitted through the bites of chiggers or larval mites infected by Orientia tsutsugamushi(O.tsutsugamushi).Omadacycline,a ...
关键词:Omadacycline Scrub typhus Orientia tsutsugamushi Targeted nextgeneration sequencing ESCHAR Case report 
Value of combining targeted emergency nursing with psychological nursing in children with febrile convulsions
《World Journal of Clinical Cases》2024年第21期4518-4526,共9页Qing Han Feng-Ru Wu Yun Hong Li-Li Gu Yu Zhu 
BACKGROUND Febrile convulsions are a common pediatric emergency that imposes significant psychological stress on children and their families.Targeted emergency care and psychological nursing are widely applied in clin...
关键词:Targeted emergency nursing Psychological nursing Children with febrile convulsions SATISFACTION Treatment compliance 
Co-infection of Chlamydia psittaci and Tropheryma whipplei: A case report被引量:1
《World Journal of Clinical Cases》2023年第29期7144-7149,共6页Zhu-Man Du Pei Chen 
BACKGROUND The co-infection of Chlamydia psittaci(C.psittaci)and Tropheryma whipplei(T.whipplei)is unusual,and the detection of pathogenic microorganisms is particularly important for patients with severe diseases or ...
关键词:Infectious diseases Chlamydia psittaci Tropheryma whipplei Targeted next generation sequencing Case report 
Clinical outcomes of targeted therapies in elderly patients aged ≥ 80 years with metastatic colorectal cancer
《World Journal of Clinical Cases》2022年第28期10066-10076,共11页Hee Ryeong Jang Hui-Young Lee Seo-Young Song Kyu-Hyoung Lim 
BACKGROUND The 5-fluorouracil-based chemotherapy combined with oxaliplatin or irinotecan is usually used in colorectal cancer(CRC).The addition of a targeted agent(TA) to this combination chemotherapy is currently the...
关键词:Combination chemotherapy Targeted agent Colorectal cancer Salvage chemotherapy Elderly patient 
Effects of targeted-edited oncogenic insulin-like growth factor-1 receptor with specific-sgRNA on biological behaviors of Hep G2 cells
《World Journal of Clinical Cases》2022年第28期10017-10030,共14页Min Yao Yin Cai Zhi-Jun Wu Ping Zhou Wen-Li Sai De-Feng Wang Li Wang Deng-Fu Yao 
Supported by Projects of the National Natural Science Foundation of China,No.81873915,No.31872738 and No.81673241;Key Plan of Nantong S&T Development,No.MS12020021;Program of Medical School S&T of Nantong University,No.2018YFC0116902。
BACKGROUND Insulin-like growth factor-1 receptor(IGF-1R)is over-expressed in hepatocellular carcinoma(HCC).However,the relationship between IGF-1R activation and HCC progression remains unidentified.AIM To investigate...
关键词:Hepatocellular carcinoma Insulin-like growth factor-1 receptor Synergistic effects Multidrug resistance Growth inhibition Biological behaviors 
Meta-analysis of gemcitabine plus nab-paclitaxel combined with targeted agents in the treatment of metastatic pancreatic cancer
《World Journal of Clinical Cases》2022年第27期9703-9713,共11页Zhong-Hui Li Yin-Jie Ma Zong-Hang Jia Yue-Yan Weng Ping Zhang Shi-Jie Zhu Fang Wang 
BACKGROUND Gemcitabine plus nab-paclitaxel(GA) is a commonly used first-line treatment regimen for metastatic pancreatic cancer,and many studies will add a novel targeted agent to this regimen for improving patient su...
关键词:Metastatic pancreatic cancer GEMCITABINE NAB-PACLITAXEL Novel targeted agent SURVIVAL 
Targeted next-generation sequencing identifies a novel nonsense mutation in ANK1 for hereditary spherocytosis:A case report
《World Journal of Clinical Cases》2022年第15期4923-4928,共6页Pan Fu Yang-Yang Jiao Kai Chen Jing-Bo Shao Xue-Lian Liao Jing-Wei Yang Sha-Yi Jiang 
Supported by the Natural Science Foundation of Shanghai Science Committee,No.18ZR1431200;Research Foundation of Shanghai Municipal Health Commission,No.20194Y0112;Clinical Research Plan of SHDC,No.SHDC2020CR4089.
BACKGROUND Hereditary spherocytosis(HS)is characterized by anemia,jaundice,splenomegaly,and cholelithiasis,and is caused by abnormal genes encoding red blood cell membrane components.The most common mutations found in...
关键词:Hereditary spherocytosis ANK1 mutation Next-generation sequencing Case report Nonsense mutation 
Diagnosis and treatment of acute graft-versus-host disease after liver transplantation:Report of six cases被引量:3
《World Journal of Clinical Cases》2021年第30期9255-9268,共14页Min Tian Yi Lyu Bo Wang Chang Liu Liang Yu Jian-Hua Shi Xue-Min Liu Xiao-Gang Zhang Kun Guo Yu Li Liang-Shuo Hu 
Supported by The National Natural Science Foundation of China,No.81870445;Scientific Research Project of Military Healthcare,No.BZZ19J004.
BACKGROUND Graft-versus-host disease(GVHD)following liver transplantation(LT)is an unpredictable complication with poor outcome.However,consensus regarding the diagnosis and therapeutic regimen for the disease is yet ...
关键词:Graft-versus-host disease Liver transplantation Donor T-lymphocytes chimerism Gut microbiota Donor-targeted serotherapy Case report 
Time to give up traditional methods for the management of gastrointestinal neuroendocrine tumours
《World Journal of Clinical Cases》2021年第29期8627-8646,共20页Ahmet Yozgat Murat Kekilli Mustafa Altay 
Neuroendocrine tumors(NETs)are a rare and heterogeneous disease group and constitute 0.5%of all malignancies.The annual incidence of NETs is increasing worldwide.The reason for the increase in the incidence of NETs is...
关键词:Enterochromaffin cells 68Ga-DOTATATE GASTROINTESTINAL Neuroendocrine tumours Somatostatin receptor Targeted peptide receptor radiotherapy 
Association between liver targeted antiviral therapy in colorectal cancer and survival benefits:An appraisal
《World Journal of Clinical Cases》2020年第11期2111-2115,共5页Qiang Wang Chao-Ran Yu 
In colorectal cancer(CRC),liver metastasis remains a major contributor to the cause of cancer-related death.Putative biomarkers,therapeutic efficacy,and drug insensitivity still pose clinical challenges for metastatic...
关键词:Colorectal cancer Liver metastasis Antiviral therapy SURVIVAL Injury status Biomarkers 
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