Supported by National Natural Science Foundation of China,No.81800721;the Postdoctoral Foundation of China,2020M671387.
BACKGROUND Scrub typhus is a naturally occurring acute infectious disease that is primarily transmitted through the bites of chiggers or larval mites infected by Orientia tsutsugamushi(O.tsutsugamushi).Omadacycline,a ...
BACKGROUND Febrile convulsions are a common pediatric emergency that imposes significant psychological stress on children and their families.Targeted emergency care and psychological nursing are widely applied in clin...
BACKGROUND The co-infection of Chlamydia psittaci(C.psittaci)and Tropheryma whipplei(T.whipplei)is unusual,and the detection of pathogenic microorganisms is particularly important for patients with severe diseases or ...
BACKGROUND The 5-fluorouracil-based chemotherapy combined with oxaliplatin or irinotecan is usually used in colorectal cancer(CRC).The addition of a targeted agent(TA) to this combination chemotherapy is currently the...
Supported by Projects of the National Natural Science Foundation of China,No.81873915,No.31872738 and No.81673241;Key Plan of Nantong S&T Development,No.MS12020021;Program of Medical School S&T of Nantong University,No.2018YFC0116902。
BACKGROUND Insulin-like growth factor-1 receptor(IGF-1R)is over-expressed in hepatocellular carcinoma(HCC).However,the relationship between IGF-1R activation and HCC progression remains unidentified.AIM To investigate...
BACKGROUND Gemcitabine plus nab-paclitaxel(GA) is a commonly used first-line treatment regimen for metastatic pancreatic cancer,and many studies will add a novel targeted agent to this regimen for improving patient su...
Supported by the Natural Science Foundation of Shanghai Science Committee,No.18ZR1431200;Research Foundation of Shanghai Municipal Health Commission,No.20194Y0112;Clinical Research Plan of SHDC,No.SHDC2020CR4089.
BACKGROUND Hereditary spherocytosis(HS)is characterized by anemia,jaundice,splenomegaly,and cholelithiasis,and is caused by abnormal genes encoding red blood cell membrane components.The most common mutations found in...
Supported by The National Natural Science Foundation of China,No.81870445;Scientific Research Project of Military Healthcare,No.BZZ19J004.
BACKGROUND Graft-versus-host disease(GVHD)following liver transplantation(LT)is an unpredictable complication with poor outcome.However,consensus regarding the diagnosis and therapeutic regimen for the disease is yet ...
Neuroendocrine tumors(NETs)are a rare and heterogeneous disease group and constitute 0.5%of all malignancies.The annual incidence of NETs is increasing worldwide.The reason for the increase in the incidence of NETs is...
In colorectal cancer(CRC),liver metastasis remains a major contributor to the cause of cancer-related death.Putative biomarkers,therapeutic efficacy,and drug insensitivity still pose clinical challenges for metastatic...