This research was funded by the National Nature Science Foundation Youth Project(Grant No.81702514);the National Natural Science Foundation of China(Grant No.81430058);the Clinical Research Project of Shanghai Municipal Commission of Health and Family Planning(Grant No.20184Y0130).
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Speckle-type POZ (pox virus and zinc finger protein) protein (SPOP) is anE3 ubiquitin ligase adaptor protein that specifically promotes the ubiquitination and proteasome degradation of proteins. SPOP mutations are...
Prostate cancer is a clinically and molecularly heterogeneous disease. Understanding the biologic underpinning of prostate cancer is necessary to best determine how biology is associated with the risk of disease progr...