Supported by The Science and Technology Department of Jilin Province,China,No.YDZJ202301ZYTS002;The Jilin Province Medical and Health Talents Project,No.2019SRCJ010.
BACKGROUND Carriers of chromosomal balanced translocations are often physically healthy with no obvious developmental problems.However,potential chromosomal imbalance in their gametes can lead to implantation failure,...
supported by the Natural Science Foundation of Hebei Province(Grant No.C2024204110);the National Key Research and Development Program of China(Grant No.2023YFD1200101-08);the National Natural Science Foundation of China(Grant Nos.32172560,31930098);the Hebei Provincial Natural Science Fund for Distinguished Young(Grant No.C2020204063);the Science Fund for Distinguished Young Scholars of Hebei Province(Grant No.C2021204049);the Innovative Research Group Project of Hebei Natural Science Foundation(Grant No.C2020204111)。
Leaf color is one of the most important breeding traits,which is closely related to the growth,development,yield and quality of Chinese cabbage.Leaf color mutants are precious materials for studying the molecular mech...
supported by the National Natural Science Foundation of China(82473914,82173808,U21A20419,81903606);Guangzhou Basic and Applied Basic Research Project(2024A04J10013,202102021272);Guangdong Provincial Key Laboratory of Construction Foundation(2017B030314030);Traditional Chinese Medicine Bureau of Guangdong Province(20231134,20231158).
Sorting nexins(SNXs)as the key regulators of sorting cargo proteins are involved in diverse diseases.SNXs can form the specific reverse vesicle transport complex(SNXs-retromer)with vacuolar protein sortings(VPSs)to so...
supported by grants from the National Key Research and Development Program of China(2021YFF1000500);the National Natural Science Foundation of China(32370272,31970273,and 31921001).
Phosphorus(P)is an essential nutrient for crop growth,making it important for maintaining food security as the global population continues to increase.Plants acquire P primarily via the uptake of inorganic phosphate(P...
supported by the National Natural Science Foundation of China(31930003 and 41976087);the National Key R&D Program of China(2018YFA0901300).
Cytochrome c maturation(CCM),a posttranslational modification involving covalent attachment of heme to polypeptides(apocyt c),is essential for the activity and cellular function of cytochromes c.Here,we identify and s...
Primary renal cell carcinoma (RCC) with metastasis is common with an estimated 30% of patients with RCC having metastases at the time of diagnosis. Evidence of metastatic RCC without a primary renal tumor is extremely...
supported by funding from the National Natural Science Foundation of China(No.82070211 to Liang Huang,No.82170167 to Xiaoxi Zhou,No.81800356 to Jin Huang);the National Key R&D Program of China(No.2022YFC2502604 to Liang Huang).
of somatic mutations of genes known to be recurrently mutated in hematologic malignancies in the peripheral blood of healthy individuals.1 When clonal hematopoiesis is associated with a mutation at a variant allele fr...
Deficiency or restriction of Zn absorption in soils is one of the most common micronutrients deficient in cereal plants. To investigate critical micronutrient interaction in zinc deficiency and zinc sufficient in soil...
This work was financially supported by the National Natural Science Foundation of China(Nos.22373025 and 22227804).
Nanopore sequencing harnesses changes in ionic current as nucleotides traverse a nanopore,enabling real-time decoding of DNA/RNA sequences.The instruments for the dynamic behavior of substances in the nanopore on the ...
supported by the Chinese Science and Technology Innovation 2030-Major Project(2022ZD0211701 and 2021ZD0200700);the National Natural Science Foundation of China(82130042,81830040 and 82371532);Shenzhen Science and Technology Serial Funds(GJHZ20210705141400002,KCXFZ20211020164543006,JCYJ20220818101615033,ZDSYS202-20606100606014,and KQTD20221101093608028).
Major depressive disorder(MDD)is a debilitating mental health condition that ranks second in the global burden of human diseases[1].Despite extensive research,the etiology and pathogenesis of MDD remain poorly underst...