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作品数:105被引量:262H指数:8
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相关领域:生物学医药卫生更多>>
相关作者:李甜夏国宏姜妍胡智强周建更多>>
相关机构:兰州交通大学上海市第十人民医院复旦大学附属肿瘤医院第二军医大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划高等学校学科创新引智计划中国博士后科学基金更多>>
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Selective recognition of PTRE1 transcripts mediated by protein-protein interaction between the m^(6)A reader ECT2 and PTRE1
《Plant Communications》2024年第11期144-156,共13页Li Yang Bo Wang Duanmu Zhao Xuechun Li Yifei Qin Ning Ouyang Zhili Xiao Zhibing Zhang Gad Galili Jiayang Li Hadas Peled-Zehavi Jian Wu 
Double first-class discipline promotion project(2021B10564001);Laboratory of Lingnan Modern Agriculture Project(NT2021001 and NG2021004).
N^(6)-methyladenosine (m^(6)A) is a prevalent internal post-transcriptional modification in eukaryotic RNAs executed by m^(6)A-binding proteins known as “readers.” Our previous research demonstrated that the Arabido...
关键词:ECT2 20S proteasome m^(6)A RNA protein interaction ARABIDOPSIS 
GhCTSF1,a short PPR protein with a conserved role in chloroplast development and photosynthesis,participates in intron splicing of rpoC1 and ycf3-2 transcripts in cotton被引量:1
《Plant Communications》2024年第6期213-229,共17页Yuzhu Huo Mengxue Cheng Meiju Tang Meng Zhang Xiaofan Yang Yating Zheng Tong Zhao Peng He Jianing Yu 
supported by the National Natural Science Foundation of China(32170367 and 32000146);the Shaanxi Fundamental Science Research Project for Chemistry&Biology(22JHZ007);the Department of Science and Technology Innovation Team Project of Shaanxi Provincial(2024RS-CXTD-72);the Fundamental Research Funds for the Central Universities(2020TS053);the Excellent Graduate Training Program of Shaanxi Normal University(LHRCCX23185).
Cotton is one of the most important textile fibers worldwide.As crucial agronomic traits,leaves play an essential role in the growth,disease resistance,fiber quality,and yield of cotton plants.Pentatricopeptide repeat...
关键词:CHLOROPLAST RNA splicing PPR protein COTTON photosynthesis 
Potential and application of abortive transcripts as a novel molecular marker of cancers
《World Journal of Experimental Medicine》2024年第2期53-61,共9页Tian-Miao Zhang Xiao-Nian Zhu Shao-Wei Qin Xue-Feng Guo Xue-Kun Xing Li-Feng Zhao Sheng-Kui 
Supported by Key Science and Technology Research and Development Program Project of Guangxi,No.AB22035017.
Abortive transcript(AT)is a 2-19 nt long non-coding RNA that is produced in the abortive initiation stage.Abortive initiation was found to be closely related to RNA polymerase through in vitro experiments.Therefore,th...
关键词:Abortive transcript Abortive initiation RNA polymerase TRANSCRIPTION Tumor marker 
Recent progress in co-detection of single-cell transcripts and proteins
《Nano Research》2024年第1期132-150,共19页Shanqing Huang Qian Fan Yidi Wang Zhi Huang Weixiong Shi Yanli Gong Ting Yang Jie Wang Lingling Wu Chaoyong Yang 
the National Natural Science Foundation of China(Nos.22293031,22004083,21927806,82227801,and 82341023);the National Key R&D Program of China(No.2019YFA0905800);the Innovative research team of high-level local universities in Shanghai(No.SHSMU-ZLCX20212601)for their financial support.
Cellular heterogeneity is a universal property of living systems,and the interrogation of single cells facilitates in-depth understanding of distinct cellular states and functions in various biological processes.Co-an...
关键词:single cell optical imaging mass spectrometry imaging single-cell RNA sequencing(scRNA-seq) co-detection 
Comprehensive analysis of the full-length transcripts and alternative splicing involved in clubroot resistance in Chinese cabbage
《Journal of Integrative Agriculture》2023年第11期3284-3295,共12页SU He-nan YUAN Yu-xiang YANG Shuang-juan WEI Xiao-chun ZHAO Yan-yan WANG Zhi-yong QIN Liu-yue YANG Zhi-yuan NIU Liu-jing LI Lin ZHANG Xiao-wei 
supported by the National Natural Science Foundation of China (31872945 and 31801874);the earmarked fund for China Agricultural Research System (CARS-23-G15);the Funds for Distinguished Young Scientists from Henan Academy of Agricultural Sciences, China (2021JQ03);the Innovation Team of Henan Academy of Agricultural Sciences, China (2021TD06)。
Chinese cabbage is an economically important Brassica vegetable worldwide, and clubroot, which is caused by the soilborne protist plant pathogen Plasmodiophora brassicae is regarded as a destructive disease to Brassic...
关键词:Chinese cabbage CLUBROOT full-length transcriptome SMRT sequencing alternative splicing 
Expression dynamics of periodic transcripts during cancer cell cycle progression and their correlation with anticancer drug sensitivity
《Military Medical Research》2023年第4期444-460,共17页Chun‑Xiao Li Jin‑Song Wang Wen‑Na Wang Dong‑Kui Xu Yan‑Tong Zhou Fang‑Zhou Sun Yi‑Qun Li Feng‑Zhu Guo Jia‑Lu Ma Xue‑Yan Zhang Meng‑Jiao Chang Bing‑He Xu Fei Ma Hai‑Li Qian 
supported by grants from the National Key Research and Development Program of China(2021YFF1201300);the National Natural Science Foundation of China(81872280,82073094);the CAMS Innovation Fund for Medical Sciences(CIFMS)(2021-I2M-1-014);the Open Issue of State Key Laboratory of Molecular Oncology(SKL-KF-2021-16);the Independent Issue of State Key Laboratory of Molecular Oncology(SKL-2021-16).
Background:The cell cycle is at the center of cellular activities and is orchestrated by complex regulatory mechanisms,among which transcriptional regulation is one of the most important components.Alternative splicin...
关键词:Cell cycle Alternative splicing Transcriptome Drug resistance Cyclin dependent kinase 4/6 inhibitor Dolichyl-phosphate mannosyltransferase polypeptide 2 
Screening Linear and Circular RNA Transcripts from Stress Granules被引量:1
《Genomics, Proteomics & Bioinformatics》2023年第4期886-893,共8页Shuai Chen Jinyang Zhang Fangqing Zhao 
supported by grants from the National Key R&D Program of China(Grant Nos.2021YFA1300500 and 2021YFA1302000);the National Natural Science Foundation of China(Grant Nos.32130020,32025009,and 91940306).
Stress granules(SGs)are cytoplasmic ribonucleoprotein assemblies formed under stress conditions and are related to various biological processes and human diseases.Previous studies have reported the regulatory role of ...
关键词:Stress granule Circular RNA Protein–RNA interaction RNA-SEQ Hepatocellular carcinoma 
Large-scale long terminal repeat insertions produced a significant set of novel transcripts in cotton被引量:2
《Science China(Life Sciences)》2023年第8期1711-1724,共14页Yan Yang Xingpeng Wen Zhiguo Wu Kun Wang Yuxian Zhu 
supported by the National Key Research and Development Program of China(2022YFF1001400);the National Natural Science Foundation of China(31690090,32200286,32070207);Foundation of Hubei Hongshan Laboratory(2021hszd014);Hubei Provincial Natural Science Foundation of China(2021CFA055,2021BBA102);the China Postdoctoral Science Foundation(2022TQ0240,2022M722470)。
Genomic analysis has revealed that the 1,637-Mb Gossypium arboreum genome contains approximately 81%transposable elements(TEs),while only 57%of the 735-Mb G.raimondii genome is occupied by TEs.In this study,we investi...
关键词:RNA-SEQ intergenic transcripts long terminal repeat epigenetic modification NUCLEOSOMES 
Newfound Coding Potential of Transcripts Unveils Missing Members of Human Protein Communities
《Genomics, Proteomics & Bioinformatics》2023年第3期515-534,共20页Se´bastien Leblanc Marie A.Brunet Jean-Franc¸ois Jacques Amina M.Lekehal Andre´a Duclos Alexia Tremblay Alexis Bruggeman-Gascon Sondos Samandi Myle`ne Brunelle Alan A.Cohen Michelle S.Scott Xavier Roucou 
supported by the Canadian Institutes for Health Research(CIHR)(Grant No.PJT175322);by a Canada Research Chair in Functional Proteomics and Discovery of Novel Proteins to Xavier Roucou.
Recent proteogenomic approaches have led to the discovery that regions of the transcriptome previously annotated as non-coding regions[i.e.,untranslated regions(UTRs),open reading frames overlapping annotated coding s...
关键词:Alternative protein Protein network Protein–protein interaction PSEUDOGENE Affinity purification mass spectrometry 
Personalized Management of Chronic Myeloid Leukemia Presenting with Ovarian Apoplexy and Review of Health Emergency Cases
《International Journal of Clinical Medicine》2023年第4期206-215,共10页Vasile Musteata 
Introduction: Chronic myeloid leukemia (CML) may significantly affect quality of life and life expectancy in the accelerated and acute phases, especially if presented with health emergencies. Objective: The purpose of...
关键词:LEUKEMIA BCR-ABL Gene Transcripts Health Emergencies Ovarian Apoplexy Tyrosine Kinase Inhibitors Survival 
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