PSEUDOGENE

作品数：27被引量：38H指数：3
导出分析报告
相关领域：医药卫生生物学更多>>
相关作者：陈昕冯芬陈沁楠魏晨晨姜黎黎更多>>
相关机构：哈尔滨医科大学内蒙古科技大学南京医科大学第二附属医院更多>>
相关期刊：《Chinese Medical Journal》《Genes & Diseases》《Journal of Biomedical Research》《Genomics, Proteomics & Bioinformatics》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划国家科技部专项基金霍英东教育基金更多>>
-
在结果中检索

检索结果分析

结果分析中...
共 条 记 录，以下是1-10
全选清除导出
参考文献引证文献引用追踪
视图：
排序：
In vivo consequences of varying degrees of OTOA alteration elucidated using knock-in mouse models and pseudogene contamination-free long-read sequencing
《Genes & Diseases》2025年第3期88-92,共5页Ju Ang Kim Bong Jik Kim Chung Lee Go Hun Seo Hane Lee Jin Hee Han Ava Niazi Joosang Park Byung Yoon Choi Sungjin Park 
supported by the National Research Foundation of Korea(NRF)grant funded by the Korean government(MSIT)(No.2021R1C1C1007980 to B.J.K.);Chungnam National University Sejong Hospital Research Fund,2022,and Chungnam National University(to B.J.K.);supported by the Basic Science Research Program through the NRF,funded by the Ministry of Education(No.2021R1A2C2092038 to B.Y.C.);Bio Core Facility Center program(No.NRF-2022M3A9G1014007 to B.Y.C.);the Basic Research Laboratory program through the NRF,funded by the Ministry of Education(No.RS-2023-0021971031482092640001 to B.Y.C.);the Technology Innovation Program(No.K_G012002572001 to B.Y.C.)funded By the Ministry of Trade,Industry&Energy(MOTIE,Korea);funded by SNUBH(Seoul National University Bundang Hospital)intramural research fund(No.13-2022-0010,02-2017-0060,16-2023-0002,13-2023-0002,16-2022-0005,13-2024-0004,and 13-2017-0013 to B.Y.C.);supported by the National Institute on Deafness and Other Communication Disorders(NIDCD);part of the US National Institutes of Health(No.R01DC018814 to S.P.).
Otoancorin(OTOA)is a glycosylphosphatidylinositol(GPI)-anchored protein mediating the attachment of the tectorial membrane(TM)to the spiral limbus(SL)in the inner ear.Homozygous or compound heterozygous mutations in O...
关键词：vivo consequences glycosylphosphatidylinositol anchored protein autosomal recessive deafness dfnb we tectorial membrane tectorial membrane tm pseudogene contamination free long read sequencing knock mouse models sensorineural hearing lossidentifying 
Combining single-cell profiling and functional analysis explores the role of pseudogenes in human early embryonic development被引量：1
《Journal of Genetics and Genomics》2024年第11期1173-1186,共14页Mengyao Sun Le Chang Liu He Li Wang Zhengyang Jiang Yanmin Si Jia Yu Yanni Ma 
supported by the National Key Research and Development Program of China(2021YFA0805703,2019YFA0801800,and 2019YFA0802600);the National Natural Science Foundation of China(82330007,82122005,92268205 and 81970101);CAMS Innovation Fund for Medical Sciences(2021-I2M1-019);Haihe Laboratory of Cell Ecosystem Innovation Fund(22HHXBSS00027)。
More and more studies have demonstrated that pseudogenes possess coding ability,and the functions of their transcripts in the development of diseases have been partially revealed.However,the role of pseudogenes in mai...
关键词：PSEUDOGENE Human early embryonic development Non-coding RNA Human embryonic stem cell 
Frequent recombination in Cynoglossus abbreviatus(Pleuronectiformes:Cynoglossidae)ribosomal 18S rDNA
《Acta Oceanologica Sinica》2024年第8期98-103,共6页Li Gong Tingqi Jiang Bilin Hu Kaixin Wang Nannan Zhang Zengliang Miao 
The Basic Scientific Research Operating Expenses of Zhejiang Provincial Universities under contract 2021JZ003;the Zhoushan Science and Technology Bureau under contract No.2021C21007;the Natural Science Foundation of Zhejiang Province under contract Y21C190023;the National Natural Science Foundation of China under contract 31272273.
The conventional theory of concerted evolution has been used to explain the lack of sequence variation in ribosomal RNA(rRNA)genes across diverse eukaryotic species.However,recent investigations into rRNA genes in fla...
关键词：ribosomal RNA tongue sole non-concerted evolution PSEUDOGENE crossing over gene conversion 
Prediction of Tumor Microenvironment Characteristics and Treatment Response in Lung Squamous Cell Carcinoma by Pseudogene OR7E47P-related Immune Genes
《Current Medical Science》2023年第6期1133-1150,共18页Ya-qi ZHAO Hao-han ZHANG Jie WU Lan LI Jing LI Hao ZHONG Yan JIN Tian-yu LEI Xin-yi ZHAO Bin XU Qi-bin SONG Jie HE 
the Wuhan University Medical Faculty Innovation Seed Fund Cultivation Project(No.TFZZ2018025);the Chen Xiao-ping Foundation for the Development of Science and Technology of Hubei Province(No.CXPJJH12000001-2020313);the National Natural Science Foundation of China(No.81670123 and No.81670144).
Objective Pseudogenes are initially regarded as nonfunctional genomic sequences,but some pseudogenes regulate tumor initiation and progression by interacting with other genes to modulate their transcriptional activiti...
关键词：PSEUDOGENE olfactory receptor family 7 subfamily E member 47 pseudogene-related immune gene tumor microenvironment IMMUNOTHERAPY lung squamous cell carcinoma 
Newfound Coding Potential of Transcripts Unveils Missing Members of Human Protein Communities
《Genomics, Proteomics & Bioinformatics》2023年第3期515-534,共20页Se´bastien Leblanc Marie A.Brunet Jean-Franc¸ois Jacques Amina M.Lekehal Andre´a Duclos Alexia Tremblay Alexis Bruggeman-Gascon Sondos Samandi Myle`ne Brunelle Alan A.Cohen Michelle S.Scott Xavier Roucou 
supported by the Canadian Institutes for Health Research(CIHR)(Grant No.PJT175322);by a Canada Research Chair in Functional Proteomics and Discovery of Novel Proteins to Xavier Roucou.
Recent proteogenomic approaches have led to the discovery that regions of the transcriptome previously annotated as non-coding regions[i.e.,untranslated regions(UTRs),open reading frames overlapping annotated coding s...
关键词：Alternative protein Protein network Protein–protein interaction PSEUDOGENE Affinity purification mass spectrometry 
The pseudogene DUXAP10 contributes to gefitinib resistance in NSCLC by repressing OAS2 expression被引量：1
《Acta Biochimica et Biophysica Sinica》2023年第1期81-90,共10页Shengnan Ren Ya Zhu Siying Wang Qinqiu Zhang Niu Zhang Xiaoteng Zou Chenchen Wei Zhaoxia Wang 
This work was supported by the grants from the National Natural Science Foundation of China(Nos.81672307,82072591,and 81703056);the Key Research and Development Plan(Social Development)of Science and Technology Department of Jiangsu Province(No.BE2019760);the“123”Advantageous Disciplines,Core Technologies and“789”Excellent Talent Training Plan of the Second Affiliated Hospital of Nanjing Medical University(No.789ZYRC202090148).
Gefitinib,an epidermal growth factor receptor-tyrosine kinase inhibitor(EGFR-TKI),is the currently recommended first-line therapy for advanced EGFR-mutant lung cancer,and understanding the mechanism of resistance is t...
关键词：NSCLC gefitinib resistance DUXAP10 EZH2 OAS2 
The pseudogenes of eukaryotic translation elongation factors (EEFs): Role in cancer and other human diseases
《Genes & Diseases》2022年第4期941-958,共18页Luigi Cristiano 
The eukaryotic translation elongation factors (EEFs), i.e. EEF1A1, EEF1A2, EEF1B2, EEF1D, EEF1G, EEF1E1 and EEF2, are coding-genes that play a central role in the elongation step of translation but are often altered i...
关键词：CANCER EEFs Non-coding RNA PSEUDOGENE TRANSLATION Translation elongation factor 
Pseudogene HMGN2P46 as a microRNA sponge to regulate HMGN2 expression via competing for miR-590-3p in severe acute pancreatitis
《BIOCELL》2022年第5期1299-1308,共10页HONGQIANG ZHAO QI LIU HAORUN LIU WEIMIN LI JIANGYANG LU 
This work was supported by National Natural Science Foundation of China[81901957];China Postdoctoral Science Foundation[2018M633723].
HMGN2 have functions in inflammatory response.However,the role of HMGN2 in severe acute pancreatitis(SAP)remains unclear.Here,our study was to discuss the role and regulatory mechanism ofHMGN2 in SAP.In this study,the...
关键词：HMGN2 PSEUDOGENE Severe acute pancreatitis INFLAMMATION miR-590-3p 
Identification of a 10-pseudogenes signature as a novel prognosis biomarker for ovarian cancer
《BIOCELL》2022年第4期999-1011,共13页YONGHUI YU SONGHUI XU ERYONG ZHAO YONGSHUN DONG JINBIN CHEN BOQI RAO JIE ZENG LEI YANG JIACHUN LU FUMAN QIU 
supported by the National Natural Science Foundation of China Grants 81872127,81602289(FQ);81872694,81673267,81473040(JL);81402753,81672303,81871876(LY);Guangzhou Science Research Program General Project Grant 201707010123(FQ);Guangzhou Municipal Scientific Research Project Grant 1201630073(FQ);Guangdong High School Young Innovative Talents Project Grant 2015KQNCX136(FQ).
The outcomes of ovarian cancer are complicated and usually unfavorable due to their diagnoses at a late stage.Identifying the efficient prognostic biomarkers to improve the survival of ovarian cancer is urgently warra...
关键词：PSEUDOGENE Ovarian cancer PROGNOSIS Risk signature Immune infiltration 
CPEB1,a novel risk gene in recent-onset schizophrenia,contributes to mitochondrial complex I defect caused by a defective provirus ERVWE1被引量：2
《World Journal of Psychiatry》2021年第11期1075-1094,共20页Ya-Ru Xia Xiao-Cui Wei Wen-Shi Li Qiu-Jin Yan Xiu-Lin Wu Wei Yao Xu-Hang Li Fan Zhu 
Supported by the National Natural Science Foundation of China,No.81971943,No.81772196,No.31470264,No.81271820,No.30870789,and No.30300117;the Stanley Foundation of United States,No.06R-1366(for Zhu F);the Medical Science Advancement Program(Basic Medical Sciences)of Wuhan University,No.TFJC 2018002.
BACKGROUND Schizophrenia afflicts 1%of the world population.Clinical studies suggest that schizophrenia patients may have an imbalance of mitochondrial energy metabolism via inhibition of mitochondrial complex I activ...
关键词：ERVWE1 CPEB1 NADH dehydrogenase ubiquinone flavoprotein 2 complex I PSEUDOGENE 
全选清除导出
共3页<123>
检索报告 对象比较 聚类工具 使用帮助 返回顶部