TRAUMATIC_BRAIN_INJURY

作品数:529被引量:1727H指数:18
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相关作者:侯立军胡锦周良辅王杨孙一睿更多>>
相关机构:复旦大学第二军医大学第三军医大学西南医院中南大学更多>>
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相关基金:国家自然科学基金天津市自然科学基金中国博士后科学基金国家重点基础研究发展计划更多>>
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Neurobehavioral effects of explosion exposure on acute and chronic traumatic brain injury in rats
《China Medical Abstracts(Internal Medicine)》2024年第1期22-23,共2页王琪 
Objective To explore the effect of nerve injury in rats by neurobehavioral experiments,in order to provide a model and idea for further clarification of the traumatic brain injury mechanism under explosion exposure.Me...
关键词:TRAUMATIC RATS INJURY 
Placenta-derived mesenchymal stem cells attenuate secondary brain injury after controlled cortical impact in rats by inhibiting matrix metalloproteinases
《BIOCELL》2024年第1期149-162,共14页PING YANG YUANXIANG LAN ZHONG ZENG YAN WANG HECHUN XIA 
financially supported by the Key Research Projects of Ningxia Hui Autonomous Region of China under Grant No.2018BCG01002(to HCX).
Background:As a form of biological therapy,placenta-derived mesenchymal stem cells(PDMSCs)exhibit considerable promise in addressing the complex pathological processes of traumaticbrain injury(TBI)due to their multi-t...
关键词:Traumatic brain injury Mesenchymal stem cells Oxidative stress Matrix metalloproteinases 
Enhanced angiogenesis by the hyaluronic acid hydrogels immobilized with a VEGF mimetic peptide in a traumatic brain injury model in rats被引量:6
《Regenerative Biomaterials》2019年第6期325-334,共10页Jiaju Lu Fengyi Guan Fuzhai Cui Xiaodan Sun Lingyun Zhao Ying Wang Xiumei Wang 
the National Natural Science Foundation of China(31771056 and 81200931);the Tsinghua University Initiative Scientific Research Program(20161080091);the 111 Project(B17026);a special fund from Key laboratory of Neurodegenerative diseases,Ministry of Education(PXM2019_026283_000002).
Angiogenesis plays an important role in brain injury repair,which contributes to the reconstruction of regenerative neurovascular niche for promoting axonal regeneration in the lesion area.As a major component of deve...
关键词:traumatic brain injury hyaluronic acid ANGIOGENESIS VEGF mimetic peptide 
Umbilical cord-derived mesenchymal stem cell transplantation combined with hyperbaric oxygen treatment for repair of traumatic brain injury被引量:24
《Neural Regeneration Research》2016年第1期107-113,共7页Hai-xiao Zhou Zhi-gang Liu Xiao-jiao Liu Qian-xue Chen 
Transplantation of umbilical cord-derived mesenchymal stem cells(UC-MSCs) for repair of traumatic brain injury has been used in the clinic. Hyperbaric oxygen(HBO) treatment has long been widely used as an adjuncti...
关键词:nerve regeneration traumatic brain injury umbilical cord mesenchymal stem cells transplantation hyperbaric oxygen rats craniocerebral trauma neurological function neural regeneration 
Intravenous transplantation of bone marrow mesenchymal stem cells promotes neural regeneration after traumatic brain injury被引量:7
《Neural Regeneration Research》2014年第9期919-923,共5页Fatemeh Anbari Mohammad Ali Khalili Ahmad Reza Bahrami Arezoo Khoradmehr Fatemeh Sadeghian Farzaneh Fesahat Ali Nabi 
supported by research center from Shahid Sadoughi University of Medical Sciences,Yazd,Iran
To investigate the supplement of lost nerve cells in rats with traumatic brain injury by intravenous administration of allogenic bone marrow mesenchymal stem cells, this study established a Wistar rat model of traumat...
关键词:nerve regeneration bone marrow mesenchymal stem cells traumatic brain injury intravenous administration cell differentiation neurologic function cerebral cortex RATS neural regeneration 
Expression Profiling of MicroRNAs in Hippocampus of Rats Following Traumatic Brain Injury被引量:2
《Journal of Huazhong University of Science and Technology(Medical Sciences)》2014年第4期548-553,共6页孙婷怡 陈晓瑞 刘子龙 赵丽丽 江永祥 屈国强 王荣帅 黄锶哲 刘良 
supported by grants from the National Natural Science Foundation of China(No.81102304);Doctoral Fund of Ministry of Education of China(No.20090142120054);Foundation of Huazhong University of Science and Technology(No.20100573)
The changes of microRNA expression in rat hippocampus after traumatic brain injury(TBI) were explored. Adult SD rats received a single controlled cortical impact injury, and the ipsilateral hippocampus was harvested...
关键词:forensic clinical medicine traumatic brain injury MICRORNA microarray technique HIPPOCAMPUS 
A correlation study of the expression of resistin and glycometabolism in muscle tissue after traumatic brain injury in rats被引量:5
《Chinese Journal of Traumatology》2014年第3期125-129,共5页Jin Peng Zhu Lielie Zhang Jiasheng Xie Songling Pan Da Wen Hao Meng Weiyang Lin Luyang Chen Daqing 
Objective: To investigate the expression pattern of resistin (RSTN) in skeletal muscle tissue and its influence on glycometabolism in rats with traumatic brain injury (TBI). Methods: Seventy-eight SD rats were ...
关键词:Brain injuries RESISTIN INSULINRESISTANCE Blood glucose Insulin sensitivity 
Effect of glycyrrhizin on traumatic brain injury in rats and its mechanism被引量:4
《Chinese Journal of Traumatology》2014年第1期1-7,共7页Gu Xiangjin Xu Jin Ma Banyou Chen Gong Gu Peiyuan Wei Dong Hu Weixing 
Objective: To investigate the neuropro- tective effects of glycyrrhizin (Gly) as well as its effect on expression of high-mobility group box 1 (HMGB1) in rats after traumatic brain injury (TBI). Methods: Male...
关键词:Glycyrrhizic acid HMGBl protein Braininjuries Neuroprotective agents 
Relationship between AQP4 expression and structural damage to the blood-brain barrier at early stages of traumatic brain injury in rats被引量:22
《Chinese Medical Journal》2013年第22期4316-4321,共6页LU Hong LEI Xiao-yan HU Hui HE Zhan-ping 
This project was supported by the National Natural Science Foundation of China (No. 81160181) and the International Cooperation Project of Hainan Province (No. Qiongke (2012) 65).Acknowledgments: We thank XIA Qing-jie from the Department of Molecular Genetics, Institute of Neurological Disease and Translation Neuroscience Center, West China Hospital, Sichuan University, China for help with molecular biology experiments.
Background Although some studies have reported that aquaporin-4 (AQP4) plays an important role in the brain edema after traumatic brain injury (TBI), little is known about the AQP4 expression in the early stage of...
关键词:brain injury  edema  blood-brain barrier  aquaporins animal experiment 
Neuroprotective effect of AG490 in experimental traumatic brain injury of rats被引量:2
《Chinese Medical Journal》2013年第15期2934-2937,共4页DU Ai-ling JI Tai-ling YANG Bin CAO Jian-feng ZHANG Xing-guang LI Yu PAN Shun ZHANG Bo HU Zhen-bo ZENG Xian-wei 
This study was supported by grants from the Natural Science Foundation of Shandong Province,the Science and Technology Research Program of Shandong Province
Background Traumatic brain injury (TBI) is a major cause of death and disability in children and young adults worldwide. Therefore, we investigated the role of AG490 in regulating brain oedema, expression of CD40 an...
关键词:AG490 traumatic brain injury brain edema CD40 neurological severity score 
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