Objective To explore the effect of nerve injury in rats by neurobehavioral experiments,in order to provide a model and idea for further clarification of the traumatic brain injury mechanism under explosion exposure.Me...
financially supported by the Key Research Projects of Ningxia Hui Autonomous Region of China under Grant No.2018BCG01002(to HCX).
Background:As a form of biological therapy,placenta-derived mesenchymal stem cells(PDMSCs)exhibit considerable promise in addressing the complex pathological processes of traumaticbrain injury(TBI)due to their multi-t...
the National Natural Science Foundation of China(31771056 and 81200931);the Tsinghua University Initiative Scientific Research Program(20161080091);the 111 Project(B17026);a special fund from Key laboratory of Neurodegenerative diseases,Ministry of Education(PXM2019_026283_000002).
Angiogenesis plays an important role in brain injury repair,which contributes to the reconstruction of regenerative neurovascular niche for promoting axonal regeneration in the lesion area.As a major component of deve...
Transplantation of umbilical cord-derived mesenchymal stem cells(UC-MSCs) for repair of traumatic brain injury has been used in the clinic. Hyperbaric oxygen(HBO) treatment has long been widely used as an adjuncti...
supported by research center from Shahid Sadoughi University of Medical Sciences,Yazd,Iran
To investigate the supplement of lost nerve cells in rats with traumatic brain injury by intravenous administration of allogenic bone marrow mesenchymal stem cells, this study established a Wistar rat model of traumat...
supported by grants from the National Natural Science Foundation of China(No.81102304);Doctoral Fund of Ministry of Education of China(No.20090142120054);Foundation of Huazhong University of Science and Technology(No.20100573)
The changes of microRNA expression in rat hippocampus after traumatic brain injury(TBI) were explored. Adult SD rats received a single controlled cortical impact injury, and the ipsilateral hippocampus was harvested...
Objective: To investigate the expression pattern of resistin (RSTN) in skeletal muscle tissue and its influence on glycometabolism in rats with traumatic brain injury (TBI). Methods: Seventy-eight SD rats were ...
Objective: To investigate the neuropro- tective effects of glycyrrhizin (Gly) as well as its effect on expression of high-mobility group box 1 (HMGB1) in rats after traumatic brain injury (TBI). Methods: Male...
This project was supported by the National Natural Science Foundation of China (No. 81160181) and the International Cooperation Project of Hainan Province (No. Qiongke (2012) 65).Acknowledgments: We thank XIA Qing-jie from the Department of Molecular Genetics, Institute of Neurological Disease and Translation Neuroscience Center, West China Hospital, Sichuan University, China for help with molecular biology experiments.
Background Although some studies have reported that aquaporin-4 (AQP4) plays an important role in the brain edema after traumatic brain injury (TBI), little is known about the AQP4 expression in the early stage of...
This study was supported by grants from the Natural Science Foundation of Shandong Province,the Science and Technology Research Program of Shandong Province
Background Traumatic brain injury (TBI) is a major cause of death and disability in children and young adults worldwide. Therefore, we investigated the role of AG490 in regulating brain oedema, expression of CD40 an...