云南高校图书馆联盟文献共享服务平台- TRAUMATIC_BRAIN

TRAUMATIC_BRAIN_INJURY: 作品数：529被引量：1727H指数：18; 导出分析报告; 相关作者：侯立军胡锦周良辅王杨孙一睿更多>>; 相关机构：复旦大学第二军医大学第三军医大学西南医院中南大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金天津市自然科学基金中国博士后科学基金国家重点基础研究发展计划更多>>

Microglial polarization pathways and therapeutic drugs targeting activated microglia in traumatic brain injury: 《Neural Regeneration Research》2026年第1期39-56,共18页Liping Shi Shuyi Liu Jialing Chen Hong Wang Zhengbo Wang; supported by the Natural Science Foundation of Yunnan Province,No.202401AS070086(to ZW);the National Key Research and Development Program of China,No.2018YFA0801403(to ZW);Yunnan Science and Technology Talent and Platform Plan,No.202105AC160041(to ZW);the Natural Science Foundation of China,No.31960120(to ZW)。; Traumatic brain injury can be categorized into primary and secondary injuries.Secondary injuries are the main cause of disability following traumatic brain injury,which involves a complex multicellular cascade.Microgl...; 关键词：animal model anti-inflammatory drug cell replacement strategy central nervous system mesenchymal stem cell MICROGLIA NEUROINFLAMMATION non-human primate signaling pathway traumatic brain injury

A macro-transection model of brain trauma for neuromaterial testing with functional electrophysiological readouts: 《Neural Regeneration Research》2025年第12期3539-3552,共14页Jessica Wiseman Raja Haseeb Basit Akihiro Suto Sagnik Middya Bushra Kabiri Michael Evans Vinoj George Christopher Adams George Malliaras Divya Maitreyi Chari; supported by awards from the EPSRC Centre for Doctoral Training in Regenerative Medicine(EP/L014904/1,to JW);an NHS bursary(to RHB);an EPSRC Healthcare Technologies award(EP/T013885/1,to DMC)。; Functional recovery in penetrating neurological injury is hampered by a lack of clinical regenerative therapies.Biomaterial therapies show promise as medical materials for neural repair through immunomodulation,struct...; 关键词：in vitro modelling multielectrode array interfacing nanoparticles neuromaterials scratch assay transecting injury traumatic brain injury

Calcium bridges built by mitochondria-associated endoplasmic reticulum membranes:potential targets for neural repair in neurological diseases: 《Neural Regeneration Research》2025年第12期3349-3369,共21页Yichen Peng Li Zhou Yaju Jin Danli Wu Na Chen Chengcai Zhang Hongpeng Liu Chunlan Li Rong Ning Xichen Yang Qiuyue Mao Jiaxin Liu Pengyue Zhang; supported by Yunnan Province Innovation Team of Prevention and Treatment for Brain Disease with Acupuncture and Tuina,No.202405AS350007;Youth Top Talent Project of 10-thousand Talent Plan in Yunnan Province,No.YNWR-QNBJ-2018-345;the National Natural Science Foundation of China,No.81960731;Joint Special Project of Traditional Chinese Medicine in Science and Technology Department of Yunnan Province,Nos.2019FF002[-008],202001AZ070001-002 and 202001AZ070001-030;Yunnan Province University Innovation Team Projects No.2019YGC04;Yunnan Province Project Education Fund,Nos.2024Y406,2024Y414(all to PZ)。; The exchange of information and materials between organelles plays a crucial role in regulating cellular physiological functions and metabolic levels.Mitochondria-associated endoplasmic reticulum membranes serve as ph...; 关键词：Alzheimer’s disease amyotrophic lateral sclerosis Ca^(2+)signaling conduction Huntington’s disease ischemic stroke MAMMALS mitochondrial dynamics neural function repair oxidative stress Parkinson’s disease traumatic brain injury

The Citron homology domain of MAP4Ks improves outcomes of traumatic brain injury: 《Neural Regeneration Research》2025年第11期3233-3244,共12页Xiaoling Zhong Wenjiao Tai Meng-Lu Liu Shuaipeng Ma Tianjin Shen Yuhua Zou Chun-Li Zhang; supported by the TARCC,Welch Foundation Award(I-1724);the Decherd Foundation;the Pape Adams Foundation,NIH grants NS092616,NS127375,NS117065,NS111776。; The mitogen-activated protein kinase kinase kinase kinases(MAP4Ks)signaling pathway plays a pivotal role in axonal regrowth and neuronal degeneration following insults.Whether targeting this pathway is beneficial to b...; 关键词：adeno-associated virus Citron homology Citron homology domain gene therapy mitogen-activated protein kinase kinase kinase kinases traumatic brain injury

Targeting capabilities of engineered extracellular vesicles for the treatment of neurological diseases: 《Neural Regeneration Research》2025年第11期3076-3094,共19页Xinyu Yang Xiangyu Gao Xiaofan Jiang Kangyi Yue Peng Luo; supported by the National Natural Science Foundation of China,Nos.82171363,82371381(to PL),82171458(to XJ);Key Research and Development Project of Shaa nxi Province,Nos.2024SF-YBXM-404(to KY)。; Recent advances in research on extracellular vesicles have significantly enhanced their potential as therapeutic agents for neurological diseases.Owing to their therapeutic properties and ability to cross the blood–b...; 关键词：Alzheimer's disease amyotrophic lateral sclerosis engineered extracellular vesicles GLIOMA ischemic stroke neurological diseases Parkinson's disease PSYCHOSIS targeted drug delivery traumatic brain injury

Nanocarrier-mediated siRNA delivery:a new approach for the treatment of traumatic brain injury-related Alzheimer's disease: 《Neural Regeneration Research》2025年第9期2538-2555,共18页Jie Jin Huajing Zhang Qianying Lu Linqiang Tian Sanqiao Yao Feng Lai Yangfan Liang Chuanchuan Liu Yujia Lu Sijia Tian Yanmei Zhao Wenjie Ren; supported by Open Project of the Key Laboratory of Trauma and Orthopedics Research Medicine in Henan Province,No.HZKFKT20220504(to YZ);the National Natural Science Foundation of China,No.32000877(to YZ);and Open Scientific Research Program of Military Logistics,No.BLB20J009(to YZ)。; Traumatic brain injury and Alzheimer's disease share pathological similarities,including neuronal loss,amyloid-βdeposition,tau hyperphosphorylation,blood-brain barrier dysfunction,neuroinflammation,and cognitive defi...; 关键词：blood-brain barrier cognitive dysfunction EXOSOMES gene silencing immunotherapy inorganic nanomaterials liposome nanoparticles NEUROINFLAMMATION polymer nanoparticles stem cells

Mitophagy in acute central nervous system injuries:regulatory mechanisms and therapeutic potentials: 《Neural Regeneration Research》2025年第9期2437-2453,共17页Siyi Xu Junqiu Jia Rui Mao Xiang Cao Yun Xu; supported by the National Natural Science Foundation of China,Nos.81920108017(to YX),82130036(to YX),82371326(to XC),82171310(to XC);the STI2030-Major Projects,No.2022ZD0211800(to YX);Jiangsu Province Key Medical Discipline,No.ZDXK202216(to YX)。; Acute central nervous system injuries,including ischemic stro ke,intracerebral hemorrhage,subarachnoid hemorrhage,traumatic brain injury,and spinal co rd injury,are a major global health challenge.Identifying optimal ...; 关键词：autophagy intracerebral hemorrhage ischemic stroke mitochondria mitochondrial biogenesis mitochondrial quality control MITOPHAGY spinal cord injury subarachnoid hemorrhage traumatic brain injury

High-dose dexamethasone regulates microglial polarization via the GR/JAK1/STAT3 signaling pathway after traumatic brain injury: 《Neural Regeneration Research》2025年第9期2611-2623,共13页Mengshi Yang Miao Bai Yuan Zhuang Shenghua Lu Qianqian Ge Hao Li Yu Deng Hongbin Wu Xiaojian Xu Fei Niu Xinlong Dong Bin Zhang Baiyun Liu; supported by research grants from the Ningbo Science and Technology Plan Project,No.2022Z143hezuo(to BL);the National Natural Science Foundation of China,No.82201520(to XD)。; Although microglial polarization and neuroinflammation are crucial cellular responses after traumatic brain injury,the fundamental regulatory and functional mechanisms remain insufficiently understood.As potent anti-i...; 关键词：apoptosis BV2 microglia DEXAMETHASONE glucocorticoid receptor GLUCOCORTICOIDS innate immune system microglial polarization neuroinflammation primary microglia traumatic brain injury

Deciphering the mechanobiology of microglia in traumatic brain injury with advanced microsystems被引量：1: 《Neural Regeneration Research》2025年第8期2304-2306,共3页Anthony Procès Sylvain Gabriele; FEDER Prostem Research Project,No.1510614(Wallonia DG06);the F.R.S.-FNRS Epiforce Project,No.T.0092.21;the F.R.S.-FNRS Cell Squeezer Project,No.J.0061.23;the F.R.S.-FNRS Optopattern Project,No.U.NO26.22;the Interreg MAT(T)ISSE Project,which is financially supported by Interreg France-Wallonie-Vlaanderen(Fonds Européen de Développement Régional,FEDER-ERDF);Programme Wallon d’Investissement Région Wallone pour les instruments d’imagerie(INSTIMAG UMONS#1910169);support from the European Research Council(ERC)under the European Union’s Horizon 2020 research and innovation programme(AdG grant agreement no.834317,Fueling Transport,PI Frédéric Saudou)。; Advanced microsystems in traumatic brain injury research:Traumatic brain injury(TBI)results from a mechanical insult to the brain,leading to neuronal and axonal damage and subsequently causing a secondary injury.Withi...; 关键词：TRAUMATIC INJURY DAMAGE

Bidirectional regulation of the brain-gut-microbiota axis following traumatic brain injury被引量：1: 《Neural Regeneration Research》2025年第8期2153-2168,共16页Xinyu You Lin Niu Jiafeng Fu Shining Ge Jiangwei Shi Yanjun Zhang Pengwei Zhuang; supported by the National Natural Science Foundation of China,No.82174112(to PZ);Science and Technology Project of Haihe Laboratory of Modern Chinese Medicine,No.22HHZYSS00015(to PZ);State-Sponsored Postdoctoral Researcher Program,No.GZC20231925(to LN)。; Traumatic brain injury is a prevalent disorder of the central nervous system.In addition to primary brain parenchymal damage,the enduring biological consequences of traumatic brain injury pose long-term risks for pati...; 关键词：traumatic brain injury brain-gut-microbiome axis gut microbiota NEUROIMMUNE immunosuppression host defense vagal afferents bacterial infection dorsal root ganglia nociception neural circuitry

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